Dissecting the interplay between the dynamics of immune responses and pathogen proliferation in vivo

Project Information

ImmProDynamics

Grant agreement ID: 714233

DOI 10.3030/714233

Project closed

EC signature date 2 December 2016

Start date 1 March 2017

End date 28 February 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 499 525,00

EU contribution € 1 499 525,00

Coordinated by

OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG
Germany

Publications

Peer reviewed articles (9)

Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression

Author(s): Sabine Brandt, Tobias M. Ballhause, Anja Bernhardt, Annika Becker, Delia Salaru, Hien Minh Le-Deffge, Alexander Fehr, Yan Fu, Lars Philipsen, Sonja Djudjaj, Andreas J. Müller, Rafael Kramann, Mahmoud Ibrahim, Robert Geffers, Chris Siebel, Berend Isermann, Florian H. Heidel, Jonathan A. Lindquist, Peter R. Mertens
Published in: Journal of the American Society of Nephrology, Issue 31/11, 2020, Page(s) 2589-2608, ISSN 1046-6673
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/asn.2019121289

Interleukin-11 receptor expression on monocytes is dispensable for their recruitment and pathogen uptake during Leishmania major infection

Author(s): Iris Baars; Juliane Lokau; Juliane Lokau; Ina Sauerland; Andreas Müller; Christoph Garbers; Christoph Garbers
Published in: Cytokine, Issue 3, 2021, ISSN 1043-4666
Publisher: Academic Press
DOI: 10.1016/j.cyto.2021.155699

Ly6G deficiency alters the dynamics of neutrophil recruitment and pathogen capture during Leishmania major skin infection

Author(s): Corinna L. Kleinholz, Monika Riek-Burchardt, Elena A. Seiß, Jonas Amore, Patricia Gintschel, Lars Philipsen, Philippe Bousso, Borna Relja, Burkhart Schraven, Juliane Handschuh, Juliane Mohr, Andreas J. Müller
Published in: Scientific Reports, Issue 11/1, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-94425-9

Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc

Author(s): Anna Krone, Yan Fu, Simon Schreiber, Johanna Kotrba, Loisa Borde, Aileen Nötzold, Christoph Thurm, Jonas Negele, Tobias Franz, Sabine Stegemann-Koniszewski, Jens Schreiber, Christoph Garbers, Aniruddh Shukla, Robert Geffers, Burkhart Schraven, Dirk Reinhold, Anne Dudeck, Annegret Reinhold, Andreas J. Müller, Sascha Kahlfuss
Published in: Scientific Reports, Issue 12/1, 2022, Page(s) 1943, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-04827-6

Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells

Author(s): Pauline Formaglio, Mohamad Alabdullah, Anastasios Siokis, Juliane Handschuh, Ina Sauerland, Yan Fu, Anna Krone, Patricia Gintschel, Juliane Stettin, Sandrina Heyde, Juliane Mohr, Lars Philipsen, Anja Schröder, Philippe A. Robert, Gang Zhao, Sahamoddin Khailaie, Anne Dudeck, Jessica Bertrand, Gerald F. Späth, Sascha Kahlfuß, Philippe Bousso, Burkhart Schraven, Jochen Huehn, Sebastian Binder, Mic
Published in: Immunity, Issue Volume 54, Issue 12, 2021, Page(s) 2724-2739.e10, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2021.09.021

Longitudinal proliferation mapping in vivo reveals NADPH oxidase-mediated dampening of Staphylococcus aureus growth rates within neutrophils

Author(s): Elena A. Seiß, Anna Krone, Pauline Formaglio, Oliver Goldmann, Susanne Engelmann, Burkhart Schraven, Eva Medina, Andreas J. Müller
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-42129-6

CD11c-expressing Ly6C+CCR2+ monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmission

Author(s): Sandrina Heyde, Lars Philipsen, Pauline Formaglio, Yan Fu, Iris Baars, Guido Höbbel, Corinna L. Kleinholz, Elena A. Seiß, Juliane Stettin, Patricia Gintschel, Anne Dudeck, Philippe Bousso, Burkhart Schraven, Andreas J. Müller
Published in: PLOS Pathogens, Issue 14/10, 2018, Page(s) e1007374, ISSN 1553-7374
Publisher: Public Library of Science
DOI: 10.1371/journal.ppat.1007374

From the Cradle to the Grave of an Infection: Host‐Pathogen Interaction Visualized by Intravital Microscopy

Author(s): Juliane Handschuh, Jonas Amore, Andreas J. Müller
Published in: Cytometry Part A, 2019, ISSN 1552-4922
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cyto.a.23938

TLR7 Sensing by Neutrophils Is Critical for the Control of Cutaneous Leishmaniasis

Author(s): Ivo B. Regli, Katiuska Passelli, Berenice Martínez-Salazar, Jonas Amore, Benjamin P. Hurrell, Andreas J. Müller, Fabienne Tacchini-Cottier
Published in: Cell Reports, Issue 31/10, 2020, Page(s) 107746, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.107746