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Mechanistic studies of metal-dependent DNA cleavage in Type II topoisomerase toward the rational design of novel anticancer drugs

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Smoothed Potential MD Simulations for Dissociation Kinetics of Etoposide To Unravel Isoform Specificity in Targeting Human Topoisomerase II

Author(s): Jissy A. Kuriappan, Neil Osheroff, Marco De Vivo
Published in: Journal of Chemical Information and Modeling, Issue 59/9, 2019, Page(s) 4007-4017, ISSN 1549-9596
DOI: 10.1021/acs.jcim.9b00605