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Late Stage Fluorination and its Applications to Drug Discovery

Deliverables

Supervisory Board of the Network

Effective nomination of the Supervisory Board of FLUDD

Website and Newsletters

Website and Newsletters regularly updated and sustained, including partner websites.

FLUDD Schools

Formal annual FLUDD school with taught training component, oral communications by all ESRs and plenary lecturers.

Public Website, Press release, Outreach, Open days, Embassy

Public website design and maintenance, including press release, outreach activities, open days, embassy.

ESR recruitment process

Effective recruitment of all ESRs according to the priniciple of transparency and non-discrimination

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Publications

Hydrodifluoromethylation of Alkenes with Difluoroacetic Acid


Published in: ISSN 1433-7851
DOI: 10.1002/anie.201903801

Hydrochlorofluoromethylation of unactivated alkenes with chlorofluoroacetic acid

Author(s): Claudio F. Meyer, Sandrine M. Hell, Jeroen B.I. Sap, Antonio Misale, Aldo Peschiulli, Daniel Oehlrich, Andrés A. Trabanco, Véronique Gouverneur
Published in: Tetrahedron, Issue 8 October 2019, 2019, Page(s) 130679, ISSN 0040-4020
DOI: 10.1016/j.tet.2019.130679

Silyl Radical-Mediated Activation of Sulfamoyl Chlorides Enables Direct Access to Aliphatic Sulfonamides from Alkenes

Author(s): Sandrine M. Hell, Claudio F. Meyer, Gabriele Laudadio, Antonio Misale, Michael C. Willis, Timothy Noël, Andrés A. Trabanco, Veronique Gouverneur
Published in: Journal of the American Chemical Society, 2019, ISSN 0002-7863
DOI: 10.1021/jacs.9b13071

Hydrosulfonylation of Alkenes with Sulfonyl Chlorides under Visible Light Activation


Published in: ISSN 1433-7851
DOI: 10.1002/anie.202004070

Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery

Author(s): Jeroen B. I. Sap, Natan J. W. Straathof, Thomas Knauber, Claudio F. Meyer, Maurice Médebielle, Laura Buglioni, Christophe Genicot, Andrés A. Trabanco, Timothy Noël, Christopher W. am Ende, Véronique Gouverneur
Published in: Journal of the American Chemical Society, Issue 142/20, 2020, Page(s) 9181-9187, ISSN 0002-7863
DOI: 10.1021/jacs.0c03881

Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ-Fluoroamines

Author(s): Giulia Roagna, David M. H. Ascough, Francesco Ibba, Anna Chiara Vicini, Alberto Fontana, Kirsten E. Christensen, Aldo Peschiulli, Daniel Oehlrich, Antonio Misale, Andrés A. Trabanco, Robert S. Paton, Gabriele Pupo, Veronique Gouverneur
Published in: Journal of the American Chemical Society, 2020, ISSN 0002-7863
DOI: 10.1021/jacs.0c05131