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Late Stage Fluorination and its Applications to Drug Discovery


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Formal annual FLUDD school with taught training component, oral communications by all ESRs and plenary lecturers.

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Hydrodifluoromethylation of Alkenes with Difluoroacetic Acid

Published in: ISSN 1433-7851
DOI: 10.1002/anie.201903801

Hydrochlorofluoromethylation of unactivated alkenes with chlorofluoroacetic acid

Author(s): Claudio F. Meyer, Sandrine M. Hell, Jeroen B.I. Sap, Antonio Misale, Aldo Peschiulli, Daniel Oehlrich, Andrés A. Trabanco, Véronique Gouverneur
Published in: Tetrahedron, Issue 8 October 2019, 2019, Page(s) 130679, ISSN 0040-4020
DOI: 10.1016/j.tet.2019.130679

Silyl Radical-Mediated Activation of Sulfamoyl Chlorides Enables Direct Access to Aliphatic Sulfonamides from Alkenes

Author(s): Sandrine M. Hell, Claudio F. Meyer, Gabriele Laudadio, Antonio Misale, Michael C. Willis, Timothy Noël, Andrés A. Trabanco, Veronique Gouverneur
Published in: Journal of the American Chemical Society, 2019, ISSN 0002-7863
DOI: 10.1021/jacs.9b13071

Hydrosulfonylation of Alkenes with Sulfonyl Chlorides under Visible Light Activation

Published in: ISSN 1433-7851
DOI: 10.1002/anie.202004070

Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery

Author(s): Jeroen B. I. Sap, Natan J. W. Straathof, Thomas Knauber, Claudio F. Meyer, Maurice Médebielle, Laura Buglioni, Christophe Genicot, Andrés A. Trabanco, Timothy Noël, Christopher W. am Ende, Véronique Gouverneur
Published in: Journal of the American Chemical Society, Issue 142/20, 2020, Page(s) 9181-9187, ISSN 0002-7863
DOI: 10.1021/jacs.0c03881

Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ-Fluoroamines

Author(s): Giulia Roagna, David M. H. Ascough, Francesco Ibba, Anna Chiara Vicini, Alberto Fontana, Kirsten E. Christensen, Aldo Peschiulli, Daniel Oehlrich, Antonio Misale, Andrés A. Trabanco, Robert S. Paton, Gabriele Pupo, Veronique Gouverneur
Published in: Journal of the American Chemical Society, 2020, ISSN 0002-7863
DOI: 10.1021/jacs.0c05131