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Novel Atg4B-inhibitors and dual [Atg4B-carbonic anhydrase] inhibitors for interfering with cytoprotective mechanisms of cancer cells in the acidic tumor micro-environment.


Synthesis and evaluation of novel benzotropolones as Atg4B inhibiting autophagy blockers

Author(s): Muhammet Tanc, Matthias Cleenewerck, Ammar Kurdi, Ria Roelandt, Wim Declercq, Guido De Meyer, Koen Augustyns, Wim Martinet, Pieter Van der Veken
Published in: Bioorganic Chemistry, Issue 87, 2019, Page(s) 163-168, ISSN 0045-2068
Publisher: Academic Press
DOI: 10.1016/j.bioorg.2019.03.021

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