Deliverables Documents, reports (16) Training material for specific critical positions in animal high containment facilities forwarded to WP5 NA Ethics Committee Best Practice Guidance NA Guidance on implementation of the 3Rs and EU Animal Experimentation Directive NA Process guidelines for designing and upgrading BSL3/3+facilities for farmed animal species including design and assessment NA Guidelines of minimum requirements and criteria for training provision and competency assessment NA Report on best practice for facility management, including emergency response and planning NA Development of a differential serological assay to separate RHDV infection from RHDV2 NA Position paper for policy makers on the biosafety of alkaline hydrolysis (biodigesters) as an alternative destruction technique to incineration based on the practical experience gained in the sector in Europe NA Biorisk management programme for facilities handling large animals to achieve CWA 15793 standard NA Novel reservoir host infection models for BSL3 zoonotic pathogens NA Report on the ethics of high containment (BSL3/BSL3+) animal infectious disease research NA List of samples available from collections and procedure for the generation of samples on-demand published on the website NA Open science and Stakeholder Engagement Strategy Report NA Guidelines for best practice in Post-Mortem facilities NA List of Activities of Interest to be maintained after the EU funding period, inventory of potential external funding sources and identification of Partner legal requirements NA Improved fish model for relevant pathogens in aquiculture NA Other (4) Three webinars available online NA Organisation of a 3Rs training event NA Adaptation of light sheet confocal microscopy to the imaging of living pathogens and host cells interactions (cell cultures and biopsies) NA Two short videos targeting veterinary laboratories and general public NA Open Research Data Pilot (1) Creation of the Data Management Plan (DMP) NA Websites, patent fillings, videos etc. (3) Creation of the Website and communication package NA Organization of 1 Summer Course at EAAP premises NA Organization of 1 Summer Course at IRTA premises NA Demonstrators, pilots, prototypes (1) Prototype telemetry sensors and behavioural analysis software NA Publications Peer reviewed articles (80) Comparative pathogenesis of peste des petits ruminants virus strains of difference virulence. Author(s): Eloiflin, Roger-Junior; Grau-Roma, Llorenç; Python, Sylvie; Mehinagic, Kemal; Godel, Aurélie; Libeau, Geneviève; Summerfield, Artur; Bataille, Arnaud; García-Nicolás, Obdulio Published in: Veterinary Resources, Issue 6, 2022, ISSN 1297-9716 Publisher: BMC DOI: 10.48350/171216 Airway Administration of Flagellin Regulates the Inflammatory Response to Pseudomonas aeruginosa Author(s): Raquel López-Gálvez, Isabelle Fleurot, Pablo Chamero, Sascha Trapp, Michel Olivier, Claire Chevaleyre, Céline Barc, Mickael Riou, Christelle Rossignol, Antoine Guillon, Mustapha Si-Tahar, Tobias May, Pascal Barbry, Andrea Bähr, Nikolai Klymiuk, Jean-Claude Sirard, Ignacio Caballero Published in: American Journal of Respiratory Cell and Molecular Biology, 2021, ISSN 1044-1549 Publisher: American Lung Association DOI: 10.1165/rcmb.2021-0125oc Pathogenicity of Different Betanodavirus RGNNV/SJNNV Reassortant Strains in European Sea Bass Author(s): Lorena Biasini; Paola Berto; Miriam Abbadi; Alessandra Buratin; Marica Toson; Andrea Marsella; Anna Toffan; Francesco Pascoli Published in: Pathogens, Issue 20760817, 2022, ISSN 2076-0817 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pathogens11040458 Development and Evaluation of a Duplex Lateral Flow Assay for the Detection and Differentiation between Rabbit Haemorrhagic Disease Virus Lagovirus europaeus/GI.1 and /GI.2 Author(s): Alba Fresco-Taboada; Mercedes Montón; Istar Tapia; Elena Soria; Juan Bárcena; Cécile Guillou-Cloarec; Ghislaine Le Gall-Reculé; Esther Blanco; Paloma Rueda Published in: Biology, Issue 20797737, 2022, ISSN 2079-7737 Publisher: MDPI DOI: 10.3390/biology11030401 Decrypting the Origin and Pathogenesis in Pregnant Ewes of a New Ovine Pestivirus Closely Related to Classical Swine Fever Virus. Author(s): Miaomiao Wang; Enrica Sozzi; José Alejandro Bohórquez; Mònica Alberch; Joan Pujols; Guillermo Cantero; Alessandra Gaffuri; Davide Lelli; Rosa Rosell; Albert Bensaid; Mariano Domingo; Lester J. Pérez; Ana Moreno; Llilianne Ganges Published in: Viruses, Issue 19994915, 2020, ISSN 1999-4915 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v12070775 The molecular basis of differential host responses to avian influenza viruses in avian species with differing susceptibility Author(s): Morris KM, Mishra A, Raut AA, Gaunt ER, Borowska D, Kuo RI, Wang B, Vijayakumar P, Chingtham S, Dutta R, Baillie K, Digard P, Vervelde L, Burt DW and Smith J Published in: Frontiers, Issue 2, 2023, ISSN 2235-2988 Publisher: Frontiers Media S. A. DOI: 10.3389/fcimb.2023.1067993 Modulation of lethal HPAIV H5N8 clade 2.3.4.4B infection in AIV pre-exposed mallards Author(s): Susanne Koethe; Lorenz Ulrich; Reiner Ulrich; Susanne Amler; Annika Graaf; Timm C. Harder; Christian Grund; Thomas C. Mettenleiter; Franz Josef Conraths; Martin Beer; Anja Globig Published in: Emerging Microbes & Infections, Issue 22221751, 2020, ISSN 2222-1751 Publisher: Nature Publishing Group DOI: 10.1080/22221751.2020.1713706 Comparative pathogenesis of peste des petits ruminants virus strains of difference virulence Author(s): Roger-Junior Eloiflin, Llorenç Grau-Roma, Sylvie Python, Kemal Mehinagic, Aurélie Godel, Geneviève Libeau, Artur Summerfield, Arnaud Bataille, Obdulio García-Nicolás Published in: Veterinary Research, Issue 12979716, 2022, ISSN 1297-9716 Publisher: Elsevier DOI: 10.1186/s13567-022-01073-6 Experimental Infection of Cattle with SARS-CoV-2 Author(s): Ulrich L., Wernike K., Hoffmann D., Mettenleiter T.C., Beer M. Published in: Emerging Infectious Diseases, Issue 10806040, 2020, ISSN 1080-6040 Publisher: US National Center for Infectious Diseases DOI: 10.3201/eid2612.203799 Contemporary selection on MHC genes in a free-living ruminant population Author(s): Huang, W., Dicks, K.L., Hadfield, J.D., Johnston, S.E., Ballingall, K.T., Pemberton, J.M. Published in: Ecology Letters, Issue 14610248, 2021, ISSN 1461-0248 Publisher: John Wileys & Sons DOI: 10.1111/ele.13957 A Trifecta of New Insights into Ovine Footrot for Infection Drivers, Immune Response, and Host-Pathogen Interactions Author(s): Blanchard A.M., Staley C.E., Shaw L., Wattegedera S.R., Baumbach C.M., Michler J.K., Rutland C., Back C., Newbold N., Entrican G., Tötemeyer S. Published in: Infection and Immunity, Issue 00199567, 2021, ISSN 0019-9567 Publisher: American Society for Microbiology DOI: 10.1128/iai.00270-21 Comparison of three air samplers for the collection of four nebulized respiratory viruses – Collection of respiratory viruses from air Author(s): Jasmin S. Kutter, Dennis de Meulder, Theo M. Bestebroer, Ard Mulders, Ron A.M. Fouchier, Sander Herfst Published in: International Journal of Indoor Environment and Health, Issue 17434955, 2021, ISSN 1743-4955 Publisher: Inderscience Enterprises DOI: 10.1111/ina.12875 Viral pathogen-induced mechanisms to antagonize mammalian interferon (IFN) signaling pathway Author(s): José M. Rojas; Alí Alejo; Verónica Martín; Noemí Sevilla Published in: Cellular and Molecular Life Sciences, Issue 14209071, 2020, ISSN 1420-9071 Publisher: Springer DOI: 10.1007/s00018-020-03671-z Differential response of RTGUTGC and RTGILL-W1 rainbow trout epithelial cell lines to viral stimulation Author(s): Rocío Simón; Patricia Martínez; Lucía González; M. Camino Ordás; Carolina Tafalla Published in: Journal of Fish Diseases, Issue Volume46, Issue4, 2023, Page(s) Pages 433-443, ISSN 0140-7775 Publisher: Blackwell Publishing Inc. DOI: 10.1111/jfd.13755 Experimental Infection of Captive Red Foxes (Vulpes vulpes) with Mycobacterium bovis Author(s): Richomme, C., Lesellier, S., Salguero, F.J., Barrat, J.L.; Boucher, J.-M.; Reyes-Reyes, J.D.; Hénault, S.; De Cruz, K.; Tambosco, J.; Michelet, L.; Boutet, J.; Elahi, R.; Lyashchenko, K.P.; O’Halloran, C.; Balseiro, A.; Boschiroli, M.L. Published in: Microorganisms, Issue 20762607, 2022, ISSN 2076-2607 Publisher: MDPI DOI: 10.3390/microorganisms10020380 Bovine endometrial MSC: mesenchymal to epithelial transition during luteolysis and tropism to implantation niche for immunomodulation. Author(s): Alexandra Calle; Soraya López-Martín; Marta Monguió-Tortajada; Francesc E. Borràs; María Yáñez-Mó; Miguel Ángel Ramírez Published in: Stem Cell Research & Therapy, Issue 17576512, 2019, ISSN 1757-6512 Publisher: BioMed Central DOI: 10.1186/s13287-018-1129-1 Sheep and Cattle Are Not Susceptible to Experimental Inoculation with Hazara Orthonairovirus, a Tick-Borne Arbovirus Closely Related to CCHFV Author(s): Hartlaub J., von Arnim F., Fast C., Somova M., Mirazimi A., Groschup M.H., Keller M. Published in: Microorganisms, Issue 20762607, 2020, ISSN 2076-2607 Publisher: Basel MDPI DOI: 10.3390/microorganisms8121927 Genome Evolution of Two Genetically Homogeneous Infectious Bursal Disease Virus Strains During Passages in vitro and ex vivo in the Presence of a Mutagenic Nucleoside Analog Author(s): Cubas-Gaona, Liliana; Flageul, Alexandre; Courtillon, Céline; Briand, Francois-Xavier; Contrant, Maud; Bougeard, Stephanie; Lucas, Pierrick; Quenault, Hélène; Leroux, Aurélie; Keita, Alassane; Amelot, Michel; Grasland, Béatrice; Blanchard, Yannick; Eterradossi, Nicolas; Brown, Paul Alun; Soubies, Sébastien Mathieu Published in: Frontiers, Issue 6, 2021, ISSN 1664-302X Publisher: Frontiers Media Identification of Differential Responses of Goat PBMCs to PPRV Virulence Using a Multi-Omics Approach Author(s): Eloiflin, R., Auray, G., Python, S., Rodrigues, V., Seveno, M., Urbach, S., El Koulali, K., Holzmuller, P., Totte, P., Libeau, G., Bataille, A., Summerfield, A. Published in: Frontiers in Immunology, Issue 16643224, 2021, ISSN 1664-3224 Publisher: Frontiers Media DOI: 10.3389/fimmu.2021.745315 Deciphering Antibody Responses to Orthonairoviruses in Ruminants Author(s): Hartlaub J., Keller M., Groschup M.H. Published in: Microorganisms, Issue 20762607, 2021, ISSN 2076-2607 Publisher: Basel MDPI DOI: 10.3390/microorganisms9071493 SARS-CoV-2 is transmitted via contact and via the air between ferrets. Author(s): Mathilde Richard; Adinda Kok; Dennis de Meulder; Theo M. Bestebroer; Mart M. Lamers; Nisreen M.A. Okba; Martje Fentener van Vlissingen; Barry Rockx; Bart L. Haagmans; Marion Koopmans; Ron A. M. Fouchier; Sander Herfst Published in: Nature Communications, Issue 20411723, 2019, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-020-17367-2 Egyptian Fruit Bats (Rousettus aegyptiacus) Were Resistant to Experimental Inoculation with Avian-Origin Influenza A Virus of Subtype H9N2, But Are Susceptible to Experimental Infection with Bat-Borne H9N2 Virus. Author(s): Nico Joel Halwe; Marco Gorka; Bernd Hoffmann; Melanie Rissmann; Angele Breithaupt; Martin Schwemmle; Martin Beer; Ahmed Kandeil; Mohamed A. Ali; Ghazi Kayali; Donata Hoffmann; Anne Balkema-Buschmann Published in: Viruses, Issue 5, 2021, ISSN 1999-4915 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v13040672 Immunophenotyping of Sheep Paraffin-Embedded Peripheral Lymph Nodes Author(s): Melzi, Eleonora; Rocchi, Mara S.; Entrican, Gary; Caporale, Marco; Palmarini, Massimo Published in: Frontiers in Immunology, Issue 16643224, 2018, ISSN 1664-3224 Publisher: Frontiers Media DOI: 10.3389/fimmu.2018.02892 A Systematic Evaluation of High-Throughput Sequencing Approaches to Identify Low-Frequency Single Nucleotide Variants in Viral Populations Author(s): King D.J., Freimanis G., Lasecka-Dykes L., Asfor A., Ribeca P., Waters R., King D.P., Laing E. Published in: Viruses, Issue 19994915, 2020, ISSN 1999-4915 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v12101187 Embryonic Trophectoderm Secretomics Reveals Chemotactic Migration and Intercellular Communication of Endometrial and Circulating MSCs in Embryonic Implantation. Author(s): Alexandra Calle; Víctor Toribio; María Yáñez-Mó; Miguel Ángel Ramírez Published in: International Journal of Molecular Sciences, Issue 14220067, 2021, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.21203/rs.3.rs-177701/v1 High sensitivity of domestic pigs to intravenous infection with HEV Author(s): Lisa Dähnert; Martin Eiden; Josephine Schlosser; Christine Fast; Charlotte Schröder; Elke Lange; Albrecht Gröner; Wolfram Schäfer; Martin H. Groschup Published in: BMC Veterinary Research, Issue 17466148, 2018, ISSN 1746-6148 Publisher: BioMed Central DOI: 10.1186/s12917-018-1713-8 Activation of OX40 and CD27 Costimulatory Signalling in Sheep through Recombinant Ovine Ligands Author(s): Rojas J.M., Alejo A., Avia J.M., Rodríguez-Martín D., Sánchez C., Alcamí A., Sevilla N., Martín V. Published in: Vaccines, Issue 2076393X, 2020, ISSN 2076-393X Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/vaccines8020333 Long-Term Protection and Serologic Response of European SeaBass Vaccinated with a Betanodavirus Virus-Like Particle Produced in Pichia pastoris Author(s): Sofie Barsøe, Anna Toffan, Francesco Pascoli, Ansgar Stratmann, Tobia Pretto, Andrea Marsella, Mériem Er-Rafik, Niccolò Vendramin, Niels J. Olesen, Dagoberto Sepúlveda, Niels Lorenzen Published in: Vaccines, Issue 2076393X, 2021, ISSN 2076-393X Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/vaccines9050447 Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs Author(s): Pedrera M., Macchi F., McLean R.K., Franceschi V., Thakur N., Russo L., Medfai L., Todd S., Tchilian E.Z., Audonnet J.C., Chappell K., Isaacs A., Watterson D., Young P.R., Marsh G.A., Bailey D., Graham S.P., Donofrio G. Published in: Vaccines, Issue 2076393X, 2020, ISSN 2076-393X Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/vaccines8010115 In vivo imaging reveals novel replication sites of a highly oncogenic avian herpesvirus in chickens Author(s): Isabelle Lantier, Corentin Mallet, Laurent Souci, Thibaut Larcher, Andele M. Conradie, Katia Courvoisier, Sascha Trapp, David Pasdeloup, Benedikt B. Kaufer, Caroline Denesvre Published in: PLOS Pathogens, Issue 15537374, 2022, ISSN 1553-7374 Publisher: PLOS DOI: 10.1371/journal.ppat.1010745 Characterisation of major histocompatibility complex class IIa haplotypes in an island sheep population. Author(s): Kara L. Dicks; Josephine M. Pemberton; Keith T. Ballingall Published in: Immunogenetics, Issue 00937711, 2019, ISSN 0093-7711 Publisher: Springer Verlag DOI: 10.1007/s00251-019-01109-w Vaccination With Recombinant Adenoviruses Expressing the Bluetongue Virus Subunits VP7 and VP2 Provides Protection Against Heterologous Virus Challenge. Author(s): José M. Rojas; Diego Barba-Moreno; Miguel Avia; Noemí Sevilla; Verónica Martín Published in: Frontiers in Veterinary Science, Issue 22971769, 2021, ISSN 2297-1769 Publisher: Frontiers Media DOI: 10.3389/fvets.2021.645561 Long term dietary vitamin D3 supplementation impacts both microbicidal and inflammatory responses to ex-vivo Mycobacterium bovis BCG challenge in dairy calves Author(s): Susana Flores-Villalva, Cian Reid, Aude Remot, Stephen V. Gordon, Kieran G. Meade Published in: ScienceDirect, Issue 8, 2023, ISSN 0165-2427 Publisher: Elsevier BV DOI: 10.1016/j.vetimm.2023.110575 Ex vivo rescue of recombinant very virulent IBDV using a RNA polymerase II driven system and primary chicken bursal cells Author(s): Liliana L. Cubas-Gaona, Romane Trombetta, Céline Courtillon, Kai Li, Xiaole Qi, Xiaomei Wang, Sofiane Lotmani, Alassane Keita, Michel Amelot, Nicolas Eterradossi, Sébastien Mathieu Soubies Published in: Scientific Reports, Issue 20452322, 2020, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-020-70095-x Defining immune correlates during latent and active chlamydial infection in sheep Author(s): Sean Wattegedera; Morag Livingstone; Stephen Maley; Mara Rocchi; Susan Lee; Yvonne Pang; Nick Wheelhouse; Kevin Aitchison; Javier Palarea-Albaladejo; David Buxton; David Longbottom; Gary Entrican Published in: Veterinary Research, Pp 1-18 (2020), Issue 17466148, 2020, ISSN 1746-6148 Publisher: BioMed Central DOI: 10.1186/s13567-020-00798-6 Detection of MERS-CoV antigen on formalin-fixed paraffin-embedded nasal tissue of alpacas by immunohistochemistry using human monoclonal antibodies directed against different epitopes of the spike protein. Author(s): Haverkamp, Ann-Kathrin; Bosch, Berend J; Spitzbarth, Ingo; Lehmbecker, Annika; Te, Nigeer; Bensaid, Albert; Segalés, Joaquim; Baumgärtner, Wolfgang; dI&I I&I-1; LS Virologie Published in: Veterinary Immunology and Immunopathology, Issue 18732534, 2019, ISSN 1873-2534 Publisher: Springer DOI: 10.1016/j.vetimm.2019.109939 Animal Models for the Study of Nucleic Acid Immunity: Novel Tools and New Perspectives. Author(s): Isabelle K. Vila; Maxence Frétaud; Dimitrios Vlachakis; Nadine Laguette; Christelle Langevin Published in: Journal of Molecular Biology, Issue 00222836, 2020, ISSN 0022-2836 Publisher: Academic Press DOI: 10.1016/j.jmb.2020.08.016 Diagnosis and Pathogenesis of Nairobi Sheep Disease Orthonairovirus Infections in Sheep and Cattle Author(s): Hartlaub J., Gutjahr B., Fast C., Mirazimi A., Keller M., Groschup M.H. Published in: Viruses, Issue 19994915, 2021, ISSN 1999-4915 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v13071250 Non-Lethal Sequential Individual Monitoring of Viremia in Relation to DNA Vaccination in Fish-Example Using a Salmon Alphavirus DNA Vaccine in Atlantic Salmon Salmo salar . Author(s): Catherine M. Collins; Katherine Lester; Jorge Del-Pozo; Bertrand Collet; Bertrand Collet Published in: Vaccines, Issue 2076393X, 2021, ISSN 2076-393X Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/vaccines9020163 Mycobacterial Infection of Precision-Cut Lung Slices Reveals Type 1 Interferon Pathway Is Locally Induced by Mycobacterium bovis but Not M. tuberculosis in a Cattle Breed Author(s): Aude Remot, Florence Carreras, Anthony Coupé, Émilie Doz-Deblauwe, Maria L. Boschiroli, John A. Browne, Quentin Marquant, Delphyne Descamps, Fabienne Archer, Abraham Aseffa, Pierre Germon, Stephen V. Gordon, Nathalie Winter Published in: Frontiers in Veterinary Science, Issue 22971769, 2021, ISSN 2297-1769 Publisher: Frontiers Media DOI: 10.3389/fvets.2021.696525 Shuni Virus Replicates at the Maternal-Fetal Interface of the Ovine and Human Placenta Author(s): Judith Oymans; Lucien van Keulen; Guus M. Vermeulen; Paul J. Wichgers Schreur; Jeroen Kortekaas Published in: Pathogens, Issue 20760817, 2020, ISSN 2076-0817 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pathogens10010017 High throughput analysis of MHC-I and MHC-DR diversity of Brazilian cattle populations Author(s): Deepali Vasoya, Priscila Silva Oliveira, Laura Agundez Muriel, Thomas Tzelos, Christina Vrettou, W. Ivan Morrison, Isabel Kinney Ferreira de Miranda Santos, Timothy Connelley Published in: HLA, Issue 20592302, 2021, ISSN 2059-2302 Publisher: John Wiley & Sons DOI: 10.1111/tan.14339 Cryobanking European Mink (Mustela lutreola) Mesenchymal Stem Cells and Oocytes Author(s): Calle A., Ramírez M.Á. Published in: International Journal of Molecular Sciences, Issue 14220067, 2022, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms23169319 Comparative Analysis of Different Inbred Chicken Lines Highlights How a Hereditary Inflammatory State Affects Susceptibility to Avian Influenza Virus Author(s): Bryson, K.J.; Sives, S.; Lee, H.-M.; Borowska, D.; Smith, J.; Digard, P.; Vervelde, L. Published in: Viruses, Issue 5, 2023, ISSN 1999-4915 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v15030591 Efficacy Assessment of Newly-designed Filtering Facemasks during the SARS-CoV-2 Pandemic Author(s): Bob Boogaard, Ali Tas, Joep Nijssen, Freek Broeren, John van der Dobbelsteen, Vincent Verhoeven, Jip Pluim, Sing Dekker, Eric Snijder, Martijn van Hemert, Sander Herfst Published in: Aerosol Air Quality Research, Issue 16808584, 2021, ISSN 1680-8584 Publisher: Chinese Association for Aerosol Research in Taiwan DOI: 10.4209/aaqr.2020.07.0424 Protective efficacy of an RBD-based Middle East respiratory syndrome coronavirus (MERS-CoV) particle vaccine in llamas Author(s): Jordi Rodon, Anna Z. Mykytyn, Guillermo Cantero, Irina C. Albulescu, Berend-Jan Bosch, Alexander Brix, Jean-Christophe Audonnet, Albert Bensaid, Júlia Vergara-Alert, Bart L. Haagmans, Joaquim Segalés Published in: One Health Outlook, Issue 25244655, 2022, ISSN 2524-4655 Publisher: BMC part of Springer Nature DOI: 10.1186/s42522-022-00068-9 A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates Author(s): José M. Rojas, Noemí Sevilla, Verónica Martín Published in: Frontiers in Veterinary Science, Issue 22971769, 2021, ISSN 2297-1769 Publisher: Frontiers Media DOI: 10.3389/fvets.2021.729879 Reverse genetics system for shuni virus, an emerging orthobunyavirus with zoonotic potential Author(s): Judith Oymans; Paul J. Wichgers Schreur; Sophie van Oort; R.P.M. Vloet; Marietjie Venter; Gorben P. Pijlman; Monique M. van Oers; Jeroen Kortekaas Published in: Viruses, Issue 19994915, 2020, ISSN 1999-4915 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v12040455 High-Resolution, 3D Imaging of the Zebrafish Gill-Associated Lymphoid Tissue (GIALT) Reveals a Novel Lymphoid Structure, the Amphibranchial Lymphoid Tissue Author(s): Alf Seljenes Dalum; Aurora Kraus; Shanawaz Khan; Erna Davydova; Dimitri Rigaudeau; Håvard Bjørgen; Adrián López-Porras; Gareth Griffiths; Geert F. Wiegertjes; Erling Olaf Koppang; Irene Salinas; Pierre Boudinot; Julien Rességuier Published in: Frontiers in immunology, Issue 16643224, 2021, ISSN 1664-3224 Publisher: Frontiers Media DOI: 10.3389/fimmu.2021.769901 Cross-Reaction or Co-Infection? Serological Discrimination of Antibodies Directed against Dugbe and Crimean-Congo Hemorrhagic Fever Orthonairovirus in Nigerian Cattle Author(s): Hartlaub J., Daodu O.B., Sadeghi B., Keller M., Olopade J., Oluwayelu D., Groschup M.H. Published in: Viruses, Issue 19994915, 2021, ISSN 1999-4915 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v13071398 Improving Tumor Retention of Effector Cells in Adoptive Cell Transfer Therapies by Magnetic Targeting. Author(s): Laura Sanz-Ortega; José M. Rojas; Domingo F. Barber Published in: Pharmaceutics, Issue 19994923, 2020, ISSN 1999-4923 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/pharmaceutics12090812 Comparison of Biological Features of Wild European Rabbit Mesenchymal Stem Cells Derived from Different Tissues Author(s): Calle A., Zamora-Ceballos M., Bárcena J., Blanco E., Ramírez M.Á. Published in: International Journal of Molecular Sciences, Issue 14220067, 2022, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms23126420 Iberian pig mesenchymal stem/stromal cells from dermal skin, abdominal and subcutaneous adipose tissues, and peripheral blood: in vitro characterization and migratory properties in inflammation Author(s): Alexandra Calle, Clara Barrajón-Masa, Ernesto Gómez-Fidalgo, Mercedes Martín-Lluch, Paloma Cruz-Vigo, Raúl Sánchez-Sánchez, Miguel Ángel Ramírez Published in: Stem Cell Research & Therapy, Issue 9/1, 2018, ISSN 1757-6512 Publisher: BioMed Central DOI: 10.1186/s13287-018-0933-y IPD-MHC: nomenclature requirements for the non-human major histocompatibility complex in the next-generation sequencing era Author(s): Giuseppe Maccari, James Robinson, Ronald E. Bontrop, Nel Otting, Natasja G. de Groot, Chak-Sum Ho, Keith T. Ballingall, Steven G. E. Marsh, John A. Hammond Published in: Immunogenetics, Issue 70/10, 2018, Page(s) 619-623, ISSN 0093-7711 Publisher: Springer Verlag DOI: 10.1007/s00251-018-1072-4 Comparative MHC nomenclature: report from the ISAG/IUIS-VIC committee 2018 Author(s): Keith T. Ballingall, Ronald E. Bontrop, Shirley A. Ellis, Unni Grimholt, John A. Hammond, Chak-Sum Ho, Jim Kaufman, Lorna J. Kennedy, Giuseppe Maccari, Donald Miller, James Robinson, Steven G. E. Marsh Published in: Immunogenetics, Issue 70/10, 2018, Page(s) 625-632, ISSN 0093-7711 Publisher: Springer Verlag DOI: 10.1007/s00251-018-1073-3 Propagation and titration of infectious bursal disease virus, including non-cell-culture-adapted strains, using ex vivo -stimulated chicken bursal cells Author(s): Sébastien Mathieu Soubies, Céline Courtillon, Mouna Abed, Michel Amelot, Alassane Keita, Andrew Broadbent, Sonja Härtle, Bernd Kaspers, Nicolas Eterradossi Published in: Avian Pathology, Issue 47/2, 2017, Page(s) 179-188, ISSN 0307-9457 Publisher: Taylor & Francis DOI: 10.1080/03079457.2017.1393044 Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein Author(s): Jordi Rodon, Nisreen M. A. Okba, Nigeer Te, Brenda van Dieren, Berend-Jan Bosch, Albert Bensaid, Joaquim Segalés, Bart L. Haagmans, Júlia Vergara-Alert Published in: Emerging Microbes & Infections, Issue 8/1, 2019, Page(s) 1593-1603, ISSN 2222-1751 Publisher: Nature Publishing Group DOI: 10.1080/22221751.2019.1685912 Detection of MERS-CoV antigen on formalin-fixed paraffin-embedded nasal tissue of alpacas by immunohistochemistry using human monoclonal antibodies directed against different epitopes of the spike protein Author(s): Ann-Kathrin Haverkamp, Berend J. Bosch, Ingo Spitzbarth, Annika Lehmbecker, Nigeer Te, Albert Bensaid, Joaquim Segalés, Wolfgang Baumgärtner Published in: Veterinary Immunology and Immunopathology, Issue 218, 2019, Page(s) 109939, ISSN 0165-2427 Publisher: Elsevier BV DOI: 10.1016/j.vetimm.2019.109939 Highly multiplexed quantitative PCR-based platform for evaluation of chicken immune responses Author(s): Dominika Borowska, Richard Kuo, Richard A. Bailey, Kellie A. Watson, Pete Kaiser, Lonneke Vervelde, Mark P. Stevens Published in: PLOS ONE, Issue 14/12, 2019, Page(s) e0225658, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0225658 Allelic nomenclature for the duplicated MHC class II DQ genes in sheep Author(s): Keith T. Ballingall, Kara Dicks, Panoraia Kyriazopoulou, Lynne Herrmann-Hoesing Published in: Immunogenetics, Issue 71/4, 2019, Page(s) 347-351, ISSN 0093-7711 Publisher: Springer Verlag DOI: 10.1007/s00251-018-1096-9 Immunological Homeostasis at the Ovine Placenta May Reflect the Degree of Maternal Fetal Interaction Author(s): Sean R. Wattegedera, Laura E. Doull, Mariya I. Goncheva, Nicholas M. Wheelhouse, Donna M. Watson, Julian Pearce, Julio Benavides, Javier Palarea-Albaladejo, Colin J. McInnes, Keith Ballingall, Gary Entrican Published in: Frontiers in Immunology, Issue 9, 2019, ISSN 1664-3224 Publisher: . DOI: 10.3389/fimmu.2018.03025 Characterisation of major histocompatibility complex class IIa haplotypes in an island sheep population Author(s): Kara L. Dicks, Josephine M. Pemberton, Keith T. Ballingall Published in: Immunogenetics, Issue 71/5-6, 2019, Page(s) 383-393, ISSN 0093-7711 Publisher: Springer Verlag DOI: 10.1007/s00251-019-01109-w Precision cut lung slices: a novel versatile tool to examine host–pathogen interaction in the chicken lung Author(s): Karen Jane Bryson, Damien Garrido, Marco Esposito, Gerry McLachlan, Paul Digard, Catherine Schouler, Rodrigo Guabiraba, Sascha Trapp, Lonneke Vervelde Published in: Veterinary Research, Issue 51/1, 2020, ISSN 1297-9716 Publisher: . DOI: 10.1186/s13567-019-0733-0 Chicken endothelial cells are highly responsive to viral innate immune stimuli and are susceptible to infections with various avian pathogens Author(s): Adrien Lion, Evelyne Esnault, Emmanuel Kut, Vanaïque Guillory, Laetitia Trapp-Fragnet, Sébastien M. Soubies, Nathalie Chanteloup, Alisson Niepceron, Rodrigo Guabiraba, Daniel Marc, Nicolas Eterradossi, Sascha Trapp, Pascale Quéré Published in: Avian Pathology, Issue 48/2, 2018, Page(s) 121-134, ISSN 0307-9457 Publisher: Taylor & Francis DOI: 10.1080/03079457.2018.1556386 Experimental Challenge of Sheep and Cattle with Dugbe Orthonairovirus, a Neglected African Arbovirus Distantly Related to CCHFV Author(s): Hartlaub J., von Arnim F., Fast C., Mirazimi A., Keller M., Groschup M.H. Published in: Viruses, Issue 19994915, 2021, ISSN 1999-4915 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/v13030372 Intramuscular DNA Vaccination of Juvenile Carp against Spring Viremia of Carp Virus Induces Full Protection and Establishes a Virus-Specific B and T Cell Response Author(s): Carmen W.E. Embregts; Dimitri Rigaudeau; Tomáš Veselý; Dagmar Pokorova; Niels Lorenzen; Jules Petit; Armel Houel; Malte Dauber; Heike Schütze; Pierre Boudinot; Geert F. Wiegertjes; Maria Forlenza Published in: Frontiers in Immunology, Issue 16643224, 2017, ISSN 1664-3224 Publisher: Frontiers Media DOI: 10.3389/fimmu.2017.01340 Mesenchymal Stem Cells in Embryo-Maternal Communication under Healthy Conditions or Viral Infections: Lessons from a Bovine Model Author(s): Alexandra Calle; Miguel Ángel Ramírez Published in: Cells, Issue 20734409, 2022, ISSN 2073-4409 Publisher: MDPI DOI: 10.3390/cells11121858 Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are features of alpacas resolving MERS-CoV infection Author(s): Nigeer Te Jordi Rodon, Maria Ballester, Mónica Pérez, Lola Pailler-García, Joaquim Segalés, Júlia Vergara-Alert, Albert Bensaid Published in: PLOS Pathogens, Issue 15537366, 2021, ISSN 1553-7366 Publisher: Public Library of Science DOI: 10.1371/journal.ppat.1009229 Evaluation of alpaca tracheal explants as an ex vivo model for the study of Middle East respiratory syndrome coronavirus (MERS-CoV) infection Author(s): Nigeer Te; Jordi Rodon; Rhea Creve; Mónica Pérez; Joaquim Segalés; Júlia Vergara-Alert; Albert Bensaid Published in: Veterinary Research, Issue 12979716, 2022, ISSN 1297-9716 Publisher: Springer Nature DOI: 10.1186/s13567-022-01084-3 Immunization With Bovine Herpesvirus-4-Based Vector Delivering PPRV-H Protein Protects Sheep From PPRV Challenge Author(s): Daniel Rodríguez-Martín, José Manuel Rojas, Francesca Macchi, Valentina Franceschi, Luca Russo, Noemí Sevilla, Gaetano Donofrío, Verónica Martín Published in: Frontiers in Immunology, Issue 16643224, 2021, ISSN 1664-3224 Publisher: Lausanne Frontiers Media DOI: 10.3389/fimmu.2021.705539 SARS-CoV and SARS-CoV-2 are transmitted through the air between ferrets over more than one meter distance. Author(s): Jasmin S Kutter; Dennis de Meulder; Theo M. Bestebroer; Pascal Lexmond; Ard Mulders; Mathilde Richard; Ron A. M. Fouchier; Sander Herfst Published in: Nature Communications, Issue 20411723, 2021, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-021-21918-6 Uncovering the core principles of the gut-lung axis to enhance innate immunity in the chicken Author(s): Saint-Martin V., Quéré P., Trapp S., Guabiraba R. Published in: Frontiers in Immunology, Issue 16643224, 2022, ISSN 1664-3224 Publisher: Frontiers Media DOI: 10.3389/fimmu.2022.956670 Enhanced replication fitness of MERS-CoV clade B over clade A strains in camelids explains the dominance of clade B strains in the Arabian Peninsula Author(s): Nigeer Te, Jordi Rodon, Mónica Pérez, Joaquim Segalés, Júlia Vergara-Alert, Albert Bensaid Published in: Emerging Microbes & Infections, Issue 22221751, 2022, ISSN 2222-1751 Publisher: Nature Publishing Group DOI: 10.1080/22221751.2021.2019559 Hemagglutinin protein of Peste des Petits Ruminants virus (PPRV) activates the innate immune response via Toll-like receptor 2 signaling Author(s): José M. Rojas, Elena Pascual, Sean R. Wattegedera, Miguel Avia, César Santiago, Verónica Martín, Gary Entrican, Noemí Sevilla Published in: Virulence, Issue 21505594, 2021, ISSN 2150-5594 Publisher: Landes Bioscience DOI: 10.1080/21505594.2021.1882246 The Intrinsic Biological Identities of Iron Oxide Nanoparticles and Their Coatings: Unexplored Territory for Combinatorial Therapies Author(s): Mulens-Arias V., Rojas J.M., Barber D.F. Published in: Nanomaterials, Issue 20794991, 2020, ISSN 2079-4991 Publisher: Basel MDPI AG DOI: 10.3390/nano10050837 Erysipelothrix rhusiopathiae-specific T-cell responses after experimental infection of chickens selectively bred for high and low serum levels of mannose-binding lectin Author(s): Wattrang, E., Sørensen Dalgaard, T., Brødsgaard Kjaerup, R. et al. Published in: Veterinary Research, 2022, ISSN 1297-9716 Publisher: Unknown Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing Author(s): Eloi R. Verrier, Christelle Langevin Published in: Frontiers in Immunology, Issue 16643224, 2021, ISSN 1664-3224 Publisher: Frontiers Media DOI: 10.3389/fimmu.2021.637399 Genome Evolution of Two Genetically Homogeneous Infectious Bursal Disease Virus Strains During Passages in vitro and ex vivo in the Presence of a Mutagenic Nucleoside Analog Author(s): Liliana L. Cubas-Gaona, Alexandre Flageul, Céline Courtillon, Francois-Xavier Briand, Maud Contrant, Stephanie Bougeard, Pierrick Lucas, Hélène Quenault, Aurélie Leroux, Alassane Keita, Michel Amelot, Béatrice Grasland, Yannick Blanchard, Nicolas Eterradossi, Paul Alun Brown, Sébastien Mathieu Soubies Published in: Frontiers in Microbiology, Issue 1664302X, 2021, ISSN 1664-302X Publisher: Frontiers Media DOI: 10.3389/fmicb.2021.678563 Potential Role of Different Fish Species as Vectors of Koi Herpesvirus (CyHV-3) Infection Author(s): Marek Matras, Magdalena Stachnik, Ewa Borzym, Joanna Maj-Paluch, Michał Reichert Published in: Journal of Veterinary Research, Issue 24508608, 2019, ISSN 2450-8608 Publisher: Warsaw De Gruyter Open DOI: 10.2478/jvetres-2019-0069 Role of Rotifers in Betanodavirus Transmission to European Sea Bass Larvae Author(s): Vázquez-Salgado L., Pascoli F., Marsella A., Biasini L., Buratin A., Pretto T., Abbadi M., Melchiotti E., Bandín I., Toffan A. Published in: Frontiers in Veterinary Science, Issue 22971769, 2022, ISSN 2297-1769 Publisher: Frontiers Media DOI: 10.3389/fvets.2022.932327 Book chapters (2) Adenovirus as Tools in Animal Health Author(s): José M. Rojas; Noemí Sevilla; Verónica Martín Published in: Adenoviruses, 2019, ISBN 978-1-78984-991-2 Publisher: IntechOpen Limited DOI: 10.5772/intechopen.79132 In Vivo Tracking of Bacterial Colonization in Different Murine Models Using Bioluminescence: The Example of Salmonella Author(s): Michaël Koczerka, Isabelle Lantier, Anne Pinard, Marie Morillon, Justine Deperne, Ohad Gal-Mor, Olivier Grépinet, Isabelle Virlogeux-Payant Published in: Bacterial Virulence, 2022, Page(s) pag. 235-248, ISBN 978-1-0716-1970-4 Publisher: Humana DOI: 10.1007/978-1-0716-1971-1_19 Conference proceedings (11) Middle East respiratory syndrome coronavirus (MERS-CoV) early infection in alpacas Author(s): Te, Nigeer; Rodon, Jordi; Vergara-Alert, Júlia; Pérez, Mónica; Segalés, Joaquim; Bensaid, Albert Published in: Proceedings of the ESVV-EPIZONE 2018 congress, 2018, Page(s) p12 Publisher: ESVV Pike, a “discreet vector” of Viral Hemorrhagic Septicemia virus (VHSV) and Infectious Hematopoietic Necrosis virus (IHNV)? Author(s): Louboutin L., Cabon J., Almeras F., Baud M., Pallandre L., Langlois Y., Dupire A., Morin T. Published in: AQUA Congress 2018, 2018, Page(s) p467 Publisher: World Aquaculture Society Progetto VetBioNet: veterinary biocontained facility network Author(s): Toffan A., Pascoli F., VetBioNet- Consortium Published in: Atti del XXIII CONVEGNO NAZIONALE S.I.P.I. Società Italiana di Patologia Ittica, 2017, Page(s) p79 Publisher: SIPI Expression of cytokines and pro-inflammatory response induced in the nasal epithelium of MERS-CoV infected alpacas (Vicugna pacos). Author(s): Te, N, Rodon, J, Pérez, M, Haagmans, B, Vergara-Alert, J, Segalés, J, Bensaid, A. Published in: SEV-GVN, XV Congress of the Spanish Society of Virology (and 11th International Global Virus Network (GVN) Meeting, Issue June 2019, 2019 Publisher: . Evaluation of an ex vivo system to rescue recombinant infectious bursal disease virus (IBDV) using chicken bursal cells and its application in the evaluation of IBDV genetic stability. Author(s): Cubas Gaonas L. L., Trombetta R., Courtillon C., Li K., Qi X., Wang X., Lotmani S., Keita A., Amelot M., Nicolas Eterradossi N., Sébastien Soubies S. M. Published in: Proceedings of the 5th Conferences Jacques Monod “Virus evolution on the mutualist - parasite continuum »,., Issue Roscoff, France, October 21-25, 2019, 2019, Page(s) 51-52 Publisher: . Middle East respiratory syndrome coronavirus (MERS-CoV) replicates in alpaca respiratory tissue explants Author(s): Rodon, J, Te, N, Pérez, M, Pujols, J, Haagmans, B, Segalés, J, Bensaid, A, Vergara-Alert, J Published in: SEV-GVN, XV Congress of the Spanish Society of Virology (and 11th International Global Virus Network (GVN) Meeting, Issue June 2019, 2019 Publisher: . Cytokine expression in the respiratory tract of MERS-CoV infected alpacas (Vicugna pacos) Author(s): Te N, Rodon J, Pérez M, Haagmans BL, Vergara-Alert J, Segalés, J, Bensaid A Published in: International Global Virus Network (GVN) Meeting, Annecy, Issue November 2018, 2018 Publisher: . Middle East Respiratory Syndrome coronavirus (MERS-CoV) vaccination efficacy in a direct-contact transmission model in llamas Author(s): Rodon, J, Te, N, Saporiti, V, Okba M.A., N, Pujols, J, Abad, X, Haagmans, B, Bosch, B-J, van Dieren, B, Vergara-Alert, J, Bensaid, A, Segalés, J Published in: XVII JORNADA DE VIROLOGIA de la Sociedad Catalana de Virología, Issue October 2018, 2018 Publisher: . An experimental vaccine based on a recombinant MERS-CoV S1-protein induces broad protective immune responses in llama Author(s): Rodon, J, Okba M.A., N, Te, N, van Dieren, B, Bosch, B-J, Bensaid, A, Segalés, J, Haagmans, B, Vergara-Alert, J Published in: 13th Annual Meeting of EPIZONE, Issue August 2019, 2019 Publisher: . Middle East respiratory syndrome coronavirus (MERS-CoV) early immune responses in an alpaca infection model Author(s): Te, N, Rodon, J, Vergara-Alert, J, Pérez, M, Segalés, J, Bensaid, A Published in: 13th Annual Meeting of EPIZONE, Issue August2019, 2019 Publisher: . Studio di patogenicità di diversi ceppi di RGNNV/SJNNV in spigola (D. labrax): risultati preliminari Author(s): Toffan A., Biasini L., Marsella A., Toson M., Pretto T., Buratin A., Pascoli F. Published in: """Atti del XXV CONVEGNO NAZIONALE S.I.P.I. Società Italiana di Patologia Ittica """, Issue https://www.sipi-online.it/wp-content/uploads/2019/08/libretto_XXV-Convegno-SIPI_GAETA.pdf, 2019, Page(s) 20 Publisher: SIPI Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
