Investigating the recognition of a novel ligand by gamma-delta T cells and the translation of this interaction into molecules for future cancer immunotherapy

Project Information

gdTCR-Ligand

Grant agreement ID: 749010

DOI 10.3030/749010

Project closed

EC signature date 10 May 2017

Start date 1 June 2017

End date 31 May 2019

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 177 598,80

EU contribution € 177 598,80

Coordinated by

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands

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Publications

Peer reviewed articles (1)

Identification of a tumor-specific allo-HLA–restricted γδTCR

Author(s): G. J. J. Kierkels, W. Scheper, A. D. Meringa, I. Johanna, D. X. Beringer, A. Janssen, M. Schiffler, T. Aarts-Riemens, L. Kramer, T. Straetemans, S. Heijhuurs, J. H. W. Leusen, E. San José, K. Fuchs, M. Griffioen, J. H. Falkenburg, L. Bongiovanni, A. de Bruin, D. Vargas-Diaz, M. Altelaar, A. J. R. Heck, L. D. Shultz, F. Ishikawa, M. I. Nishimura, Z. Sebestyén, J. Kuball
Published in: Blood Advances, Issue 3/19, 2019, Page(s) 2870-2882, ISSN 2473-9537
Publisher: American Society of Hematology
DOI: 10.1182/bloodadvances.2019032409

Intellectual Property Rights

Patent (4)

BISPECIFIC MOLECULES COMPRISING GAMMA-DELTA TCR AND T-CELL OR NK CELL BINDING DOMAIN

Application/Publication number: WO 2019156566
Date: 2019-02-10

COMPOSITIONS AND METHODS FOR CELL TARGETING THERAPIES

Application/Publication number: WO 2018211115
Date: 2018-05-18

BISPECIFIC MOLECULES COMPRISING GAMMA-DELTA TCR AND T-CELL OR NK CELL BINDING DOMAIN

Application/Publication number: WO 2019156566
Date: 2019-02-10
Applicant(s): UNIVERSITAIR MEDISCH CENTRUM UTRECHT

COMPOSITIONS AND METHODS FOR CELL TARGETING THERAPIES

Application/Publication number: WO 2018211115
Date: 2018-05-18
Applicant(s): UNIVERSITAIR MEDISCH CENTRUM UTRECHT