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Analytics for Biologics

Deliverables

Publication of advertising for open ESR positions

For acquiring the ESR advertising for open positions will be published in different media.

Project Website

Quotations about the preparation of the Website and their maintenance will be defined and applied. The content of the Website will defined at the kick-off meeting.

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Publications

FLASHDeconv: Ultrafast, high-quality feature deconvolution for top-down proteomics

Author(s): Kyowon Jeong, Jihyung Kim, Manasi Gaikwad, Siti Nurul Hidayah, Laura Heikaus, Hartmut Schlüter, Oliver Kohlbacher
Published in: 2019
DOI: 10.1101/714915

Glycoform-resolved FcɣRIIIa affinity chromatography–mass spectrometry

Author(s): Steffen Lippold, Simone Nicolardi, Elena Domínguez-Vega, Anna-Katharina Heidenreich, Gestur Vidarsson, Dietmar Reusch, Markus Haberger, Manfred Wuhrer, David Falck
Published in: mAbs, Issue 11/7, 2019, Page(s) 1191-1196, ISSN 1942-0870
DOI: 10.1080/19420862.2019.1636602

Proteoform-Resolved FcɤRIIIa Binding Assay for Fab Glycosylated Monoclonal Antibodies Achieved by Affinity Chromatography Mass Spectrometry of Fc Moieties

Author(s): Steffen Lippold, Simone Nicolardi, Manfred Wuhrer, David Falck
Published in: Frontiers in Chemistry, Issue 7, 2019, Page(s) 1-10, ISSN 2296-2646
DOI: 10.3389/fchem.2019.00698

Monitoring glycation levels of a bispecific monoclonal antibody at subunit level by ultrahigh resolution MALDI FT-ICR mass spectrometry

Author(s): Christoph Gstöttner, Dietmar Reusch, Markus Haberger, Irina Dragan, Peter van Veelen, David P. A. Kilgour, Yury O. Tsybin, Yuri E.M. van der Burgt, Manfred Wuhrer, Simone Nicolardi
Published in: mAbs, 2019, ISSN 1942-0870
DOI: 10.1080/19420862.2019.1682403

Intact protein bioanalysis by liquid chromatography – High-resolution mass spectrometry

Author(s): Peter Bults, Baubek Spanov, Oladapo Olaleye, Nico C. van de Merbel, Rainer Bischoff
Published in: Journal of Chromatography B, Issue 1110-1111, 2019, Page(s) 155-167, ISSN 1570-0232
DOI: 10.1016/j.jchromb.2019.01.032

Structural and In Vitro Functional Comparability Analysis of Altebrel™, a Proposed Etanercept Biosimilar: Focus on Primary Sequence and Glycosylation

Author(s): Ramin Fazel, Yudong Guan, Behrouz Vaziri, Christoph Krisp, Laura Heikaus, Amirhossein Saadati, Siti Nurul Hidayah, Manasi Gaikwad, Hartmut Schlüter
Published in: Pharmaceuticals, Issue 12/1, 2019, Page(s) 14, ISSN 1424-8247
DOI: 10.3390/ph12010014

Preparing Proteoforms of Therapeutic Proteins for Top-Down Mass Spectrometry

Author(s): Siti Nurul Hidayah, Manasi Gaikwad, Laura Heikaus, Hartmut Schlüter
Published in: Proteoforms [Working Title], 2020
DOI: 10.5772/intechopen.89644