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Learning and PREdiction based on the PREnatal CONnectome FInGerprint

Objective

"Endeavours towards a more profound understanding of the neural architecture enabling the staggering cognitive abilities of the human brain hold high promises regarding diagnosis and treatment of various diseases affecting the neural system. The novel paradigm of brain connectomics has opened a wealth of insights into the individual differences, emergence, development, plasticity and disease specific re-organization of macro-scale brain networks composed by interconnected and synchronously operating neural units.

Fetal neuroimaging, and in particular fetal magnetic resonance imaging (MRI) provides increasingly rich insights into the rapid prenatal neurodevelopment shaping the human connectome and establishing its capability to enable cognition or adapt and re-organize during disease. However, the exploration and study of this complex, highly multi-dimensional connectivity architecture, and its rapid change during gestation is still hampered by several limitations.

PRECONFIG aims to overcome these limitations by developing novel techniques for the reliable and accurate capturing of structural and functional MRI brain connectivity in utero and integrating them into a quantitative model providing a complex feature-set that characterizes the developing fetal connectome (""fetal connectome fingerprint"").

Ultimately, the project will deliver a canonical reference model, and algorithm implementation for artefact removal, brain network development modelling and detailed characterization of developmental disorders based on fetal MRI. Additionally it will provide a standard basis for reproducible and comparable research targeting the fetal connectome. Based on this, it will provide a proof-of-concept on the expediency of computational statistics and machine learning based stratification and prediction for clinical use of fetal MRI.
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Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2016

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Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 178 156,80
Address
SPITALGASSE 23
1090 Wien
Austria

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Region
Ostösterreich Wien Wien
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 178 156,80
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