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A TRranslational approach to Identify Biomarkers for Asthma and Lung function impairment

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Publications

Asthma genetics revisited: understanding disease mechanisms by studying ethnically diverse groups

Author(s): Erik Melén
Published in: The Lancet Respiratory Medicine, Issue 8/5, 2020, Page(s) 427-429, ISSN 2213-2600
DOI: 10.1016/s2213-2600(20)30044-8•

Integration of gene expression and DNA methylation identifies epigenetically controlled modules related to PM2.5 exposure

Author(s): Simon Kebede Merid, Mariona Bustamante, Marie Standl, Jordi Sunyer, Joachim Heinrich, Nathanaël Lemonnier, Daniel Aguilar, Josep Maria Antó, Jean Bousquet, Loreto Santa-Marina, Aitana Lertxundi, Anna Bergström, Inger Kull, Åsa M. Wheelock, Gerard H. Koppelman, Erik Melén, Olena Gruzieva
Published in: Environment International, Issue 146, 2021, Page(s) 106248, ISSN 0160-4120
DOI: 10.1016/j.envint.2020.106248

A Gap Between Asthma Guidelines and Management for Adolescents and Young Adults

Author(s): Maria Ödling, Niklas Andersson, Jenny Hallberg, Catarina Almqvist, Christer Janson, Anna Bergström, Erik Melén, Inger Kull
Published in: The Journal of Allergy and Clinical Immunology: In Practice, 2020, ISSN 2213-2198
DOI: 10.1016/j.jaip.2020.05.034

Air pollution and IgE sensitization in four European birth cohorts - the MeDALL project

Author(s): Erik Melén, Marie Standl, Ulrike Gehring, Hicran Altug, Josep Maria Antó, Dietrich Berdel, Anna Bergström, Jean Bousquet, Joachim Heinrich, Gerard H. Koppelman, Inger Kull, Christian Lupinek, Iana Markevych, Tamara Schikowski, Elisabeth Thiering, Rudolf Valenta, Marianne van Hage, Andrea von Berg, Judith M. Vonk, Magnus Wickman, Alet Wijga, Olena Gruzieva
Published in: Journal of Allergy and Clinical Immunology, 2020, ISSN 0091-6749
DOI: 10.1016/j.jaci.2020.08.030

A novel whole blood gene expression signature for asthma, dermatitis, and rhinitis multimorbidity in children and adolescents

Author(s): Nathanaël Lemonnier, Erik Melén, Yale Jiang, Stéphane Joly, Camille Ménard, Daniel Aguilar, Edna Acosta‐Perez, Anna Bergström, Nadia Boutaoui, Mariona Bustamante, Glorisa Canino, Erick Forno, Juan Ramon González, Judith Garcia‐Aymerich, Olena Gruzieva, Stefano Guerra, Joachim Heinrich, Inger Kull, Jesús Ibarluzea Maurolagoitia, Loreto Santa‐Marina Rodriguez, Elisabeth Thiering, Magnus
Published in: Allergy, Issue 75/12, 2020, Page(s) 3248-3260, ISSN 0105-4538
DOI: 10.1111/all.14314

On Genetics, Lung Developmental Biology, and Adult Lung Function

Author(s): Erik Melén, Gerard H. Koppelman, Stefano Guerra
Published in: American Journal of Respiratory and Critical Care Medicine, Issue 202/6, 2020, Page(s) 791-793, ISSN 1073-449X
DOI: 10.1164/rccm.202006-2123ed

Assessment of chronic bronchitis and risk factors in young adults: Results from BAMSE

Author(s): Gang Wang, Jenny Hallberg, Petra Um Bergström, Christer Janson, Göran Pershagen, Olena Gruzieva, Marianne van Hage, Antonios Georgelis, Anna Bergström, Inger Kull, Anders Lindén, Erik Melén
Published in: European Respiratory Journal, Issue 2020, 2020, Page(s) 2002120, ISSN 0903-1936
DOI: 10.1183/13993003.02120-2020

Tackling the Complexity of the Exposome: Considerations from the Gunma University Initiative for Advanced Research (GIAR) Exposome Symposium

Author(s): Pei Zhang, Manish Arora, Romanas Chaleckis, Tomohiko Isobe, Mohit Jain, Isabel Meister, Erik Melén, Matthew Perzanowski, Federico Torta, Markus R. Wenk, Craig E. Wheelock
Published in: Metabolites, Issue 9/6, 2019, Page(s) 106, ISSN 2218-1989
DOI: 10.3390/metabo9060106

Early-life risk factors for reversible and irreversible airflow limitation in young adults: findings from the BAMSE birth cohort

Author(s): Gang Wang, Inger Kull, Anna Bergström, Jenny Hallberg, Petra Um Bergström, Stefano Guerra, Goran Pershagen, Olena Gruzieva, Marianne van Hage, Antonios Georgelis, Christer Janson, Anders Lindén, Erik Melén
Published in: Thorax, 2020, Page(s) thoraxjnl-2020-215884, ISSN 0040-6376
DOI: 10.1136/thoraxjnl-2020-215884

DNA methylation in childhood asthma: an epigenome-wide meta-analysis

Author(s): Cheng-Jian Xu, Cilla Söderhäll, Mariona Bustamante, Nour Baïz, Olena Gruzieva, Ulrike Gehring, Dan Mason, Leda Chatzi, Mikel Basterrechea, Sabrina Llop, Maties Torrent, Francesco Forastiere, Maria Pia Fantini, Karin C Lødrup Carlsen, Tari Haahtela, Andréanne Morin, Marjan Kerkhof, Simon Kebede Merid, Bianca van Rijkom, Soesma A Jankipersadsing, Marc Jan Bonder, Stephane Ballereau, Cornelis J
Published in: The Lancet Respiratory Medicine, 2018, ISSN 2213-2600
DOI: 10.1016/S2213-2600(18)30052-3

Promoting respiratory public health through epigenetics research: an ERS Environment Health Committee workshop report

Author(s): Erik Melén, Robert Barouki, Maeve Barry, H. Marike Boezen, Barbara Hoffmann, Susanne Krauss-Etschmann, Gerard H. Koppelman, Bertil Forsberg
Published in: European Respiratory Journal, Issue 51/4, 2018, Page(s) 1702410, ISSN 0903-1936
DOI: 10.1183/13993003.02410-2017

Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis

Author(s): Olena Gruzieva, Cheng-Jian Xu, Paul Yousefi, Caroline Relton, Simon Kebede Merid, Carrie V. Breton, Lu Gao, Heather E. Volk, Jason I. Feinberg, Christine Ladd-Acosta, Kelly Bakulski, Charles Auffray, Nathanaël Lemonnier, Michelle Plusquin, Akram Ghantous, Zdenko Herceg, Tim S. Nawrot, Costanza Pizzi, Lorenzo Richiardi, Franca Rusconi, Paolo Vineis, Manolis Kogevinas, Janine F. Felix, Liesbeth Dui
Published in: Environmental Health Perspectives, Issue 127/5, 2019, Page(s) 057012, ISSN 0091-6765
DOI: 10.1289/ehp4522

Chronic Airway Diseases Early Stratification (CADSET): a new ERS Clinical Research Collaboration

Author(s): Alvar Agusti, Rosa Faner, Gavin Donaldson, Elise Heuvelin, Robab Breyer-Kohansal, Erik Melén, Anke H. Maitland-van der Zee, Jørgen Vestbo, James P. Allinson, Lowie E.G.W. Vanfleteren, Maarten van den Berge, Ian M. Adcock, Lies Lahousse, Guy Brusselle, Jadwiga A. Wedzicha
Published in: European Respiratory Journal, Issue 53/3, 2019, Page(s) 1900217, ISSN 0903-1936
DOI: 10.1183/13993003.00217-2019

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

Author(s): Christel M. Middeldorp, Janine F. Felix, Anubha Mahajan, Mark I. McCarthy
Published in: European Journal of Epidemiology, Issue 34/3, 2019, Page(s) 279-300, ISSN 0393-2990
DOI: 10.1007/s10654-019-00502-9

Genomic interactions with exposure to inhaled pollutants

Author(s): Stephanie J. London, Erik Melén
Published in: Journal of Allergy and Clinical Immunology, Issue 143/6, 2019, Page(s) 2011-2013.e1, ISSN 0091-6749
DOI: 10.1016/j.jaci.2019.04.008

Dietary antioxidant intake in school age and lung function development up to adolescence

Author(s): Emmanouela Sdona, Jenny Hallberg, Niklas Andersson, Sandra Ekström, Susanne Rautiainen, Niclas Håkansson, Alicja Wolk, Inger Kull, Erik Melén, Anna Bergström
Published in: European Respiratory Journal, Issue 55/2, 2020, Page(s) 1900990, ISSN 0903-1936
DOI: 10.1183/13993003.00990-2019

Childhood asthma in the new omics era

Author(s): Korneliusz Golebski, Michael Kabesch, Erik Melén, Uroš Potočnik, Cornelis M. van Drunen, Susanne Reinarts, Anke H. Maitland-van der Zee, Susanne J.H. Vijverberg
Published in: Current Opinion in Allergy and Clinical Immunology, Issue 20/2, 2020, Page(s) 155-161, ISSN 1528-4050
DOI: 10.1097/aci.0000000000000626

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

Author(s): Simon Kebede Merid, Alexei Novoloaca, Gemma C. Sharp, Leanne K. Küpers, Alvin T. Kho, Ritu Roy, Lu Gao, Isabella Annesi-Maesano, Pooja Jain, Michelle Plusquin, Manolis Kogevinas, Catherine Allard, Florianne O. Vehmeijer, Nabila Kazmi, Lucas A. Salas, Faisal I. Rezwan, Hongmei Zhang, Sylvain Sebert, Darina Czamara, Sheryl L. Rifas-Shiman, Phillip E. Melton, Debbie A. Lawlor, Göran Pershagen, Carr
Published in: Genome Medicine, Issue 12/1, 2020, ISSN 1756-994X
DOI: 10.1186/s13073-020-0716-9

Male sex is strongly associated with IgE-sensitization to airborne but not food allergens: results up to age 24 years from the BAMSE birth cohort

Author(s): Erik Melén, Anna Bergström, Inger Kull, Catarina Almqvist, Niklas Andersson, Anna Asarnoj, Magnus P. Borres, Antonis Georgellis, Göran Pershagen, Marit Westman, Marianne van Hage, Natalia Ballardini
Published in: Clinical and Translational Allergy, Issue 10/1, 2020, ISSN 2045-7022
DOI: 10.1186/s13601-020-00319-w

Understanding allergic multimorbidity within the non-eosinophilic interactome

Author(s): Daniel Aguilar, Nathanael Lemonnier, Gerard H. Koppelman, Erik Melén, Baldo Oliva, Mariona Pinart, Stefano Guerra, Jean Bousquet, Josep M. Anto
Published in: PLOS ONE, Issue 14/11, 2019, Page(s) e0224448, ISSN 1932-6203
DOI: 10.1371/journal.pone.0224448

Exposure to environmental phthalates during preschool age and obesity from childhood to young adulthood

Author(s): Anna Zettergren, Niklas Andersson, Kristin Larsson, Inger Kull, Erik Melén, Antonios Georgelis, Marika Berglund, Christian Lindh, Anna Bergström
Published in: Environmental Research, Issue 192, 2021, Page(s) 110249, ISSN 0013-9351
DOI: 10.1016/j.envres.2020.110249

Linking COPD epidemiology with pediatric asthma care: Implications for the patient and the physician

Author(s): Erik Melén, Stefano Guerra, Jenny Hallberg, Deborah Jarvis, Sanja Stanojevic
Published in: Pediatric Allergy and Immunology, 2019, ISSN 0905-6157
DOI: 10.1111/pai.13054