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New hope for the PAH patient: A Novel Therapeutic for Pulmonary Arterial Hypertension (PAH)

Deliverables

KOL Engagement, Communication & Dissemination

Engagement, communication & dissemination of recent development and progress on ATXA’s lead drug NTP42 including with key opinion leaders (KOLs) and other stakeholders of relevance to pulmonary arterial hypertension (PAH).

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Publications

Efficacy of the thromboxane receptor antagonist NTP42 alone, or in combination with sildenafil, in the sugen/hypoxia-induced model of pulmonary arterial hypertension

Author(s): Eamon P. Mulvaney, Helen M. Reid, Lucia Bialesova, Pedro Mendes-Ferreira, Rui Adão, Carmen Brás-Silva, B. Therese Kinsella
Published in: European Journal of Pharmacology, Issue 889, 2020, Page(s) 173658, ISSN 0014-2999
DOI: 10.1016/j.ejphar.2020.173658

Differential expression of the TPα and TPβ isoforms of the human T Prostanoid receptor during chronic inflammation of the prostate: Role for FOXP1 in the transcriptional regulation of TPβ during monocyte-macrophage differentiation

Author(s): Eamon P. Mulvaney, Áine G. O'Sullivan, Sarah B. Eivers, Helen M. Reid, B. Therese Kinsella
Published in: Experimental and Molecular Pathology, Issue 110, 2019, Page(s) 104277, ISSN 0014-4800
DOI: 10.1016/j.yexmp.2019.104277

NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension

Author(s): Eamon P. Mulvaney, Helen M. Reid, Lucia Bialesova, Annie Bouchard, Dany Salvail, B. Therese Kinsella
Published in: BMC Pulmonary Medicine, Issue 20/1, 2020, ISSN 1471-2466
DOI: 10.1186/s12890-020-1113-2

NTP42, an antagonist of the thromboxane receptor, attenuates experimentally-induced pulmonary arterial hypertension

Author(s): T Kinsella, E Mulvaney, HM Reid
Published in: European Respiratory Journal, 2019, Page(s) PA5048

Efficacy of the novel thromboxane receptor antagonist NTP42 alone, or in combination with Sildenafil, in the sugen/hypoxia-induced model of pulmonary arterial hypertension

Author(s): T Kinsella, E Mulvaney, HM Reid
Published in: European Journal of Cardiology, Issue 40, 2019, Page(s) P3670