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Safe home-based portable peritoneal dialysis system that offers simpler dialysis and improved quality of life for patients

Project description

A disruptive change in peritoneal dialysis

Due to population ageing, chronic kidney disease (CKD) has become a public health problem affecting about 10 % of the adult population and leading millions of people to premature death. In the last stages of CKD, when the kidney cannot effectively filter waste from the blood, patients require dialysis. Haemodialysis (HD) or peritoneal dialysis (PD) can be applied. Despite PD’s patient cognitive and functional outcomes, most patients still undergo HD in special clinics. The EU-funded Warrick X1 project aims to bring a great, revolutionary relief with the liberDi’s system – the first safe and portable PD system. It will offer simpler dialysis at home, reducing possible human errors and improving patients’ quality of life.

Objective

End Stage Kidney Disease (ESKD) or End Stage Renal Disease (ESRD), the fifth and last stage of Chronic Kidney Disease
(CKD), is recognised as a major public health problem. It occurs where kidneys are no longer capable of sufficiently filtering
waste products from the blood. With kidney function at less than 10 %, a kidney transplant or an external means of filtering is
needed. The latter consists of either Haemodialysis (HD) or Peritoneal Dialysis (PD). Globally, we are seeing an increasing
prevalence in ESRD. This is caused by an aging population in the west, socio-economic factors, increasing hypertension,
and growing diabetes and obesity epidemics.
The technical complexity of market offerings can inhibit many patients from choosing PD. HD takes an average of 4 hours
per treatment session and occurs 3 times a week while PD occurs 4 times a day with each exchange requiring 40 minutes
on average. Most dialysis occurs in specific dialysis centres and hospitals, adding further time for travel. Non-compliance
with treatment schedules are a particular issue with PD. This makes it difficult for doctors to calculate correct treatment plans
as patients may not share this information with their doctor. Non-compliance can be as high as 53%, decreasing efficacy of
the treatment leading to poorer health overall and speeds up rate of decline.
liberDi revolutionises traditional PD making it the first logical choice for dialysis patients. They developed Warrick X1, a smart, real-time and portable device acting as Virtual Dialysis Center. It’s lightweight, easy to set up and allows patients carry out their dialysis at home, at work or while travelling. Warrick X1 has the user at the very core of its design to ensure ease of use: smart automation, catheters and sterile connectors. The system utilises a disposable that holds a smart peristaltic pump designed to improve adherence to protocol, and reduce human errors, while saving time via fluid flow rate and management.

Call for proposal

H2020-EIC-SMEInst-2018-2020

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Sub call

H2020-SMEInst-2018-2020-2

Funding Scheme

SME - SME instrument

Coordinator

LIBERDI LTD
Net EU contribution
€ 2 160 725,00
Address
64 HA-TAKHANA STREET
3055102 Binyamina-Giv'at Ada
Israel

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost
€ 3 086 750,00