Objective
Excessive use of pesticides in Europe has led to serious contamination of soil and water and presents growing threat to human and animal health. We propose to improve the sensitivity of biosensors used both for detecting incidental or chronic environmental contamination by ant cholinesterase pesticides and/or monitoring the efficiency of remediation of polluted sites. The enzyme acetyl cholinesterase is the target of organophosphates and carbonates, two major pesticides currently used in agriculture. We will employ a 'state-of-the-art' approach, utilizing X-ray crystallography, structure analysis, site-directed autogenesis and large-scale production, using suitable expression systems. This will enable us to produce new bio engineered targets both more sensitive to and more selective for pesticides of interest, and also possess creased stability. This will permit us to provide our industrial partner with deliverables suitable for production of novel biosensors possessing the specificity and shelf life required for manufacturing field kits.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- natural sciences chemical sciences inorganic chemistry inorganic compounds
- natural sciences earth and related environmental sciences geology mineralogy crystallography
- agricultural sciences agriculture, forestry, and fisheries agriculture
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
34060 Montpellier
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.