Objective
Novel anti-microbial agents are needed to overcome problems of resistance and provide protection against infection. The control of microbial growth is also an essential part of product preservation in the cosmeceutical industry. Despite high throughput screening the discovery rate of novel ant microbial compounds has declined. We aim to reverse this trend by exploiting biodiversity within the uncultured microbial populations in the environment and clone habitat met genomes using bacterial artificial chromosomes. To evaluate the cloning procedure habitat diversity will be analysed at the functional and taxonomic level. Targeted assays will identify ant microbial activities of clones for use in control of infections, as transferral applications and as preservatives for pharmaceuticals. Thus we aim to combine chemical novelty with novelty in application.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugs
- natural sciencesbiological sciencesecologyecosystems
- natural sciencesbiological sciencesgeneticschromosomes
- natural sciencesbiological sciencesgeneticsgenomes
You need to log in or register to use this function
Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
COVENTRY
United Kingdom