Objective
This project aims to provide new tissue engineering technologies for therapeutic treatments, which will ultimately have major social impact by contributing to the challenge of providing lifelong health for our society at an affordable cost. The main aim is the development of advanced functional materials that are needed for improved quality of life of thousands of patients suffering from cartilage or bone tissue loss or malfunctioning. The improved therapy suggested herein will result in a decreased morbidity and mortality of patients with reduction of the overall costs in EU healthcare. A major objective is the development of tissue engineering (TE) products that can be used for bone TE, cartilage TE or for an osteochondral TE strategy. Natural origin scaffolds mainly based on algae & chatoyant will be used for bone andcartilage. Cewrmaic bi-physic calcium phosphates scaffolds will be obtain from mineralised red algae. For theosteochondral approach, specific technologies will be developed to produce complex bi-material (polymer/ceramic) constructs. An all range of adequate processing techniques to obtained suitable scaffolds will be developed. One of the main innovations will be the development and use of specific software packages for designing patient specific scaffolds that will be combined with the production of the scaffolds by means of 3D plotting methodologies. Other techniques will include melt based processing and solvent-based techniques. The scaffolds will also be loaded with arrange of growth factors including several bone-morph genetic proteins other GF in the TGF- family. Primary cells and progenitor cells obtained from animals and later on from human patients will be used to develop the tissue-engineered products. Cell culturing methodologies will be optimised and specific ways of controlling the cultures evolution into the desired phenotypes will be developed. In-vivo functionality assessment experiments will also be carried out.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences computer and information sciences software
- natural sciences biological sciences microbiology phycology
- medical and health sciences medical biotechnology tissue engineering
- natural sciences chemical sciences polymer sciences
- medical and health sciences medical biotechnology implants artificial bone
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-NMP-1
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
BRAGA
Portugal
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.