Objetivo Electrical stimulation of neurons is a recognised therapeutic approach for the treatment of neurodegenerative pathologies (Parkinson disease etc). These techniques could have a high impact on treatments of other pathologies like epilepsy or blindness. Available commercial devices based on metalised electrodes degrade in physiological environments and induce reactive gliosis, incompatible with fabrication of implants, where a long term stability is mandatory and a closer neuro-electronic interface is required to lower the neuronal activation threshold.The high resolution required for vision and the stimulation of graded potential neurons need complex and very precise stimulators. DREAMS propose to study and fabricate novel types of nanotransducers, based on artificial nanocrystalline diamond (NCD) that exhibits extreme biocompatibility and stability in physiological media. NCD coated and functionalised metallic electrodes or non- metalised CMOS devices will be fabricated, leading to novel active neural c ell-hybrid structures and biocompatible implants to restore a useful vision. Survival of neurons and retinal cells will be evaluated and in-vitro stability and the ability to activate neurones will be tested. DREAMS will lead to the fabrication of matrixes of Field Effect Transistors that can be validated for stimulation of the retina as well as for readout of the retinal signals in-vivo. Ámbito científico medical and health sciencesbasic medicineneurologyepilepsymedical and health sciencesclinical medicineophthalmologymedical and health sciencesbasic medicinepathologymedical and health sciencesbasic medicineneurologyparkinsonmedical and health sciencesmedical biotechnologyimplants Programa(s) FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006. Tema(s) NMP-2004-3.4.1.1-1 - Towards "converging" technologies NMP-2004-3.4.2.1-1 - Interfacial phenomena in materials Convocatoria de propuestas FP6-2004-NMP-TI-4 Consulte otros proyectos de esta convocatoria Régimen de financiación STREP - Specific Targeted Research Project Coordinador COMMISSARIAT À L'ENERGIE ATOMIQUE Aportación de la UE Sin datos Dirección Bâtiment Le Ponant D, 25 rue Leblanc PARIS Francia Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo UNIVERSITY COLLEGE LONDON Reino Unido Aportación de la UE Sin datos Dirección Gower Street LONDON Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos FORSCHUNGSZENTRUM JUELICH GMBH Alemania Aportación de la UE Sin datos Dirección Leo-Brandt-Strasse JUELICH Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos TECHNISCHE UNIVERSITAET MUENCHEN Alemania Aportación de la UE Sin datos Dirección Arcistrasse 21 MUENCHEN Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE Francia Aportación de la UE Sin datos Dirección 101 rue Tolbiac PARIS Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos
