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Content archived on 2024-06-18

Medical Diagnostics based on Exhaled-air Analysis with Laser Absorption Spectroscopy

Objective

"The objective of this project is to develop a sensor based on laser absorption spectroscopy (LAS) for the medical diagnosis of one or more human diseases by measuring biomarkers in breath. Biomarkers are volatile compounds present in trace amounts in the exhaled air whose concentrations correlate with the presence or absence of a disease or metabolic condition. A well-known example is acetone in the breath of diabetes patients.
The project will be carried out at the University of Oxford in the group of Dr. Grant Ritchie. The disease(s) will be selected in the first phase of the project taking into consideration the relevance of a non-invasive alternative diagnosis, the requirements in terms of sensitivity and selectivity of the LAS sensor, and the biomarkers that would have to be measured. Subsequently, a sensitive LAS experiment aimed at detecting the selected biomarkers will be designed and implemented. Techniques to preconcentrate the targeted biomarkers and to filter out compounds interfering with the measurements will be investigated and implemented. To test and benchmark the sensor, ""artificial"" breath with realistic concentrations of biomarkers will be produced and measured. Tests on real breath samples will be carried out if the sensor shows successful performance with the artificial samples.
The project is significant in view of its potential applications in the field of fast and non-invasive medical diagnostics."

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2012-IEF
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
EU contribution
€ 221 606,40
Address
WELLINGTON SQUARE UNIVERSITY OFFICES
OX1 2JD Oxford
United Kingdom

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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