Objective The emergence of Antibiotic-resistant bacteria (ARB) is a global problem, having recently been elevated to the top three threats identified by the World Health Organisation (WHO), and subject of numerous national and international government activities, including the Trans-Atlantic Task Force on Antimicrobial Resistance established by the US and EU presidencies. The estimated costs of ARB are around € 1.5 Billion per year in Europe, with an estimated 25,000 deaths (European Center for Disease prevention and Control/European Medicines Agency “time to react”). While the threat of antimicrobial resistance is growing, so are the challenges to bringing forward new therapeutic options for patients infected with resistant organisms. There is a need for a better understanding of how antimicrobial resistance is evolving globally, of what novel molecular mechanisms can be exploited as new forms of antimicrobial therapy and of how to more efficiently develop new treatments so they can be more rapidly brought to patients in need. The over-arching concept of New Drugs for Bad Bugs (ND4BB) is to create an innovative public-private collaborative partnership that will positively impact all aspects of ARB through the discovery and development of novel agents for the treatment, prevention and management of patients with bacterial infections. COMBACTE is one of the first projects to be launched under this programme with the aim of developing a broad European network of fully capable and Good Clinical Practice (GCP) compliant clinical investigation sites to execute clinical trials enabling the registration of novel agents to be used in the treatment of patients with bacterial infections. The growth and application of the network will be supported with robust microbiologic surveillance data and clinical epidemiologic data. To reduce the time and or cost of clinical development, novel clinical trial designs will be outlined and supported through analysis of publically available and consortium-shared non-clinical and clinical data. In addition to executing the initial set of clinical trials, investigations of patient and pathogen-related biomarkers and the logistical and decision making impact of rapid diagnostics will be conducted. Fields of science natural sciencesbiological sciencesmicrobiologybacteriologymedical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceantibiotic resistance Programme(s) FP7-JTI - Specific Programme "Cooperation": Joint Technology Initiatives Topic(s) IMI-JU-06-2012-01-02 - ND4BB Topic 1: Innovative Trial Design & Clinical Drug Development - Subtopic 1B Call for proposal IMI-JU-06-2012 See other projects for this call Funding Scheme JTI-CP-IMI - Joint Technology Initiatives - Collaborative Project (IMI) Coordinator ASTRAZENECA AB EU contribution No data Address Vastra Maelarhamnen 151 85 Sodertaelje Sweden See on map Region Östra Sverige Stockholm Stockholms län Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Jörgen Jensen (Project Manager) Principal investigator Hasan Jafri (Senior Director, Clinical Research and Development) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (38) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITAIR MEDISCH CENTRUM UTRECHT Netherlands EU contribution € 30 784 817,00 Address HEIDELBERGLAAN 100 3584 CX Utrecht See on map Region West-Nederland Utrecht Utrecht Activity type Higher or Secondary Education Establishments Administrative Contact Renzo Dettingmeijer (Mr) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CLINIQUES UNIVERSITAIRES SAINT-LUC ASBL Belgium EU contribution € 719 243,00 Address AVENUE HIPPOCRATE 10 1200 Bruxelles / Brussel See on map Region Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Activity type Other Administrative Contact Renaud Mazy (Mr) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data KLINIKUM DER UNIVERSITAET ZU KOELN Germany EU contribution € 2 428 336,00 Address Kerpener Strasse 62 50937 Koeln See on map Region Nordrhein-Westfalen Köln Köln, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Petra Schreiner-Kaub (-) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Centre hospitalier universitaire de Limoges France EU contribution € 48 977 229,00 Address avenue Martin-Luther-King 2 87000 Limoges See on map Region Nouvelle-Aquitaine Limousin Haute-Vienne Activity type Research Organisations Administrative Contact Xavier FRETILLE (Mr) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA Spain EU contribution € 862 572,00 Address C ROSSELLO 132 PLANTA 05 08036 Barcelona See on map Region Este Cataluña Barcelona Activity type Research Organisations Administrative Contact Samantha Mardell (Ms) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CENTRE HOSPITALIER UNIVERSITAIRE DEBESANCON Participation ended France EU contribution € 4 380,00 Address 3 BD ALEXANDRE FLEMING 25030 BESANCON CEDEX See on map Region Bourgogne-Franche-Comté Franche-Comté Doubs Activity type Research Organisations Administrative Contact Sophie DEPIERRE (Mrs) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH Germany EU contribution € 1 762 638,00 Address INHOFFENSTRASSE 7 38124 Braunschweig See on map Region Niedersachsen Braunschweig Braunschweig, Kreisfreie Stadt Activity type Research Organisations Administrative Contact Michael Strätz (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution € 895 653,00 Address RUE DE TOLBIAC 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Muriel BOUAS (Mrs) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITEIT ANTWERPEN Belgium EU contribution € 8 369 379,00 Address PRINSSTRAAT 13 2000 Antwerpen See on map Region Vlaams Gewest Prov. Antwerpen Arr. Antwerpen Activity type Higher or Secondary Education Establishments Administrative Contact Anne Adams (Mrs) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITE DE GENEVE Switzerland EU contribution € 5 167 190,00 Address RUE DU GENERAL DUFOUR 24 1211 Geneve See on map Region Schweiz/Suisse/Svizzera Région lémanique Genève Activity type Higher or Secondary Education Establishments Administrative Contact Stephan HARBARTH (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data JULIUS CLINICAL RESEARCH BV Netherlands EU contribution € 1 567 067,00 Address BROEDERPLEIN 41-43 3703 CD Zeist See on map Region West-Nederland Utrecht Utrecht Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Patrick Beekman (MSc) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITAETSKLINIKUM FREIBURG Germany EU contribution € 509 217,00 Address HUGSTETTER STRASSE 49 79106 Freiburg See on map Region Baden-Württemberg Freiburg Freiburg im Breisgau, Stadtkreis Activity type Higher or Secondary Education Establishments Administrative Contact Jürgen Dreyer (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS Participation ended Switzerland EU contribution No data Address RUE DU BUGNON 21 1011 Lausanne See on map Region Schweiz/Suisse/Svizzera Région lémanique Vaud Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Marie-Christine Francioli (Mrs) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data STICHTING RADBOUD UNIVERSITEIT Participation ended Netherlands EU contribution No data Address HOUTLAAN 4 6525 XZ Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Administrative Contact Maarten van Langen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data NORTH BRISTOL NATIONAL HEALTH SERVICE TRUST United Kingdom EU contribution € 1 184 970,00 Address SOUTHMEAD HOSPITAL, SOUTHMEAD ROAD, WESTBURY ON TRYM BS10 5NB Bristol See on map Region South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Bristol, City of Activity type Research Organisations Administrative Contact Alasdair MacGowan (Professor) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITE JOSEPH FOURIER GRENOBLE 1 Participation ended France EU contribution € 5 918,00 Address Avenue Centrale, Domaine Universitaire 621 38041 GRENOBLE See on map Activity type Higher or Secondary Education Establishments Administrative Contact Christian Brambilla (Directeur de Laboratoire) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD. United Kingdom EU contribution No data Address Great West Road 980 TW89GS Brentford See on map Region London Outer London — West and North West Hounslow and Richmond upon Thames Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Sally Miles (-) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data JANSSEN PHARMACEUTICA NV Belgium EU contribution No data Address TURNHOUTSEWEG 30 2340 Beerse See on map Region Vlaams Gewest Prov. Antwerpen Arr. Turnhout Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Celine Van den Broeke (Ms) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data SERVICIO ANDALUZ DE SALUD Spain EU contribution € 1 179 018,00 Address AVENIDA DE LA CONSTITUCION 18 41071 Sevilla See on map Region Sur Andalucía Sevilla Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Virginia Nieto (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CHU de Pointe-à-Pitre France EU contribution € 39 614,00 Address Route de Chauvel 97159 Pointe-à-Pitre Pointe-à-Pitre See on map Administrative Contact Chantal LERUS (Mme) Links Contact the organisation Opens in new window Total cost No data LINKOPINGS UNIVERSITET Sweden EU contribution € 57 934,00 Address CAMPUS VALLA 581 83 Linkoping See on map Region Östra Sverige Östra Mellansverige Östergötlands län Activity type Higher or Secondary Education Establishments Administrative Contact Gunilla Avefeldt (Mrs) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON Greece EU contribution € 57 934,00 Address 6 CHRISTOU LADA STR 10561 Athina See on map Region Αττική Aττική Κεντρικός Τομέας Αθηνών Activity type Higher or Secondary Education Establishments Administrative Contact Thomas Sfikopoulos (Professor) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data EBERHARD KARLS UNIVERSITAET TUEBINGEN Germany EU contribution € 1 018 710,00 Address GESCHWISTER-SCHOLL-PLATZ 72074 Tuebingen See on map Region Baden-Württemberg Tübingen Tübingen, Landkreis Activity type Higher or Secondary Education Establishments Administrative Contact Gisela Bauer-Haffter (Biologist) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITAET GREIFSWALD Germany EU contribution € 870 128,00 Address DOMSTRASSE 11 17489 Greifswald See on map Region Mecklenburg-Vorpommern Mecklenburg-Vorpommern Vorpommern-Greifswald Activity type Higher or Secondary Education Establishments Administrative Contact Andrea Völker (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITE LYON 1 CLAUDE BERNARD France EU contribution € 858 140,00 Address BOULEVARD DU 11 NOVEMBRE 1918 NUM43 69622 Villeurbanne Cedex See on map Region Auvergne-Rhône-Alpes Rhône-Alpes Rhône Activity type Higher or Secondary Education Establishments Administrative Contact Javier Olaiz (Dr) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Netherlands EU contribution € 1 136 553,00 Address DR MOLEWATERPLEIN 40 3015 GD Rotterdam See on map Region West-Nederland Zuid-Holland Groot-Rijnmond Activity type Higher or Secondary Education Establishments Administrative Contact Michael Huizer (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER Spain EU contribution € 174 934,00 Address CALLE ROSSELLO 149 PUERTA BJS 08036 Barcelona See on map Region Este Cataluña Barcelona Activity type Other Administrative Contact Pastora Martinez Samper (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data SERVICIO MADRILENO DE SALUD Spain EU contribution € 228 934,00 Address Paseo De la Castellana, 280 28046 MADRID See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Antonio Portolés Pérez (Mr) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE FOUNDATION FOR MEDICAL RESEARCH INFRASTRUCTURAL DEVELOPMENT AND HEALTH SERVICES NEXT TO THE MEDICAL CENTER TEL AVIV Israel EU contribution € 57 934,00 Address WEIZMANN STREET 6 64239 Tel Aviv See on map Activity type Research Organisations Administrative Contact Michal Roll (Dr) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data INSTITUTO NACIONAL DE SAUDE DR. RICARDO JORGE Portugal EU contribution € 57 934,00 Address AVENIDA PADRE CRUZ 1649-016 Lisboa See on map Region Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Activity type Research Organisations Administrative Contact Maria Manuela Carvalho (Doctor) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data AO Documentation and Publishing Foundation, Clinical Investigation and Documentation Switzerland EU contribution € 57 934,00 Address Clavadelerstrasse 7270 Davos See on map Activity type Research Organisations Administrative Contact Virginie Schubert (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data FONDAZIONE IRCCS CA' GRANDA - OSPEDALE MAGGIORE POLICLINICO Italy EU contribution € 57 934,00 Address VIA FRANCESCO SFORZA 28 20122 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Other Administrative Contact MANUELA MARTORANA (MRS) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK France EU contribution No data Address 30 BD SAINT-JACQUES BATIMENT B 75014 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Alicja Szofer-Araya (Mrs) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITAT ZURICH Switzerland EU contribution € 240 766,00 Address RAMISTRASSE 71 8006 Zurich See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Higher or Secondary Education Establishments Administrative Contact Kelly Turner (Scientific Manager) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data DA VOLTERRA SAS France EU contribution No data Address RUE DE CHARONNE 172 LE DORIAN BATIMENT B 75011 PARIS See on map Region Ile-de-France Ile-de-France Paris Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Pierre-Alain BANDINELLI (Mr) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data The Medicines Company United States EU contribution No data Address Sylvan Way 07054 Parsippany See on map Administrative Contact Michelle Linfesty (Senior Director, Program Management) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data PFIZER LIMITED United Kingdom EU contribution No data Address RAMSGATE ROAD CT13 9NJ Sandwich See on map Region South East (England) Kent East Kent Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Hanah Hurst (Mrs) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data EUROPEAN FORUM FOR GOOD CLINICAL PRACTICE Belgium EU contribution € 100 000,00 Address RUE DE WASHINGTON 40 1050 Bruxelles / Brussel See on map Region Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Activity type Other Administrative Contact Fanny Senez (Mrs) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data