Obiettivo Until the age of biotechnology, treatment options for children and adolescents with severe arthritis, inflammatory bowel diseases and other serious diseases with chronic inflammation were limited. Advances in understanding the pathophysiology of the inflammatory responses have led to the development of a new class of medications that are capable of inhibiting selectively the principal mediators of inflammation and tissue damage. The introduction of these new immunomodulators, which are collectively termed biologics, has opened a new era in the treatment of inflammatory diseases. Recent reports however suggest unexpected increases in adverse - or serious events -associated with the use of these biologics. PHARMACHILD aims to detect, assess and understand long term and short term side effects of the use of biologics by studying the pharmacovigilance in a large international cohort of patients with Juvenile Idiopathic Arthritis (children and young adults) in order to support regulatory decisions on marketing authorizations for these products.There is a clear need for a study that will enable the promotion of more effective and safer use of biologics in JIA as children and young adolescents represent an especially vulnerable patient group, JIA is the most common chronic disease of childhood treated with biologics, and data available from adults cannot be extrapolated to children. PHARMACHILD brings together leading European scientists in the field of infectious diseases, immunity, inflammation and oncology. Our network combines resources from international organizations and existing national registries. This combination will enable us to achieve the critical mass (in terms of expertise and resources) to identify the risk factors for developing adverse events, to elucidate the mechanisms involved in the adverse events (such as latent infection reactivation) and to develop methodologies for screening and predicting patients at risk. Campo scientifico medical and health sciencesclinical medicinerheumatologymedical and health scienceshealth sciencesinflammatory diseasesmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsmedical and health sciencesclinical medicinegastroenterologyinflammatory bowel diseasemedical and health scienceshealth sciencesinfectious diseases Programma(i) FP7-HEALTH - Specific Programme "Cooperation": Health Argomento(i) HEALTH.2010.4.2-3 - Adverse Drug Reaction Research. FP7-HEALTH-2010-single-stage Invito a presentare proposte FP7-HEALTH-2010-single-stage Vedi altri progetti per questo bando Meccanismo di finanziamento CP-FP - Small or medium-scale focused research project Coordinatore UNIVERSITAIR MEDISCH CENTRUM UTRECHT Contributo UE € 501 446,00 Indirizzo HEIDELBERGLAAN 100 3584 CX Utrecht Paesi Bassi Mostra sulla mappa Regione West-Nederland Utrecht Utrecht Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Efdokia Chatzoudi (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (8) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto ISTITUTO GIANNINA GASLINI Italia Contributo UE € 1 241 550,00 Indirizzo VIA GEROLAMO GASLINI 5 16147 Genova Mostra sulla mappa Regione Nord-Ovest Liguria Genova Tipo di attività Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Contatto amministrativo Nicolino Ruperto (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato ASKLEPIOS KLINIK SANKT AUGUSTIN GMBH Germania Contributo UE € 41 700,00 Indirizzo ARNOLD JANSSEN STRASSE 29 53757 SANKT AUGUSTIN Mostra sulla mappa Tipo di attività Other Contatto amministrativo Gerd Horneff (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Westfälische Wilhelms-Universität Münster Germania Contributo UE € 240 564,00 Indirizzo SCHLOSSPLATZ 2 48149 MUENSTER Mostra sulla mappa Regione Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Ingo Niendorf (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato THE UNIVERSITY OF MANCHESTER Regno Unito Contributo UE € 248 948,00 Indirizzo OXFORD ROAD M13 9PL Manchester Mostra sulla mappa Regione North West (England) Greater Manchester Manchester Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Liz Fay (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato DEUTSCHES RHEUMA FORSCHUNGSZENTRUMBERLIN Germania Contributo UE € 82 602,00 Indirizzo CHARITEPLATZ 1 10117 Berlin Mostra sulla mappa Regione Berlin Berlin Berlin Tipo di attività Research Organisations Contatto amministrativo Petra Starke (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM Paesi Bassi Contributo UE € 169 800,00 Indirizzo DR MOLEWATERPLEIN 40 3015 GD Rotterdam Mostra sulla mappa Regione West-Nederland Zuid-Holland Groot-Rijnmond Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Annemieke Steenbergen (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato STICHTING RADBOUD UNIVERSITEIT Paesi Bassi Contributo UE € 297 000,00 Indirizzo HOUTLAAN 4 6525 XZ Nijmegen Mostra sulla mappa Regione Oost-Nederland Gelderland Arnhem/Nijmegen Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Maarten Van Langen (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITY COLLEGE LONDON Contributo UE € 150 366,00 Indirizzo GOWER STREET WC1E 6BT LONDON Mostra sulla mappa Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Greta Borg-Carbott (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato