Objective Nematodes are among the most serious threats to livestock. They cause disease and death but they also compromise production. Even a mild infection can cause a relative protein deficiency and reduce weight gain by 25% . In the UK sheep industry alone, nematode infection costs over 100 million Euros a year .The mainstay of current control measures is anthelmintic treatment but this is threatened by the evolution of drug resistance in parasite populations. Alternative or supplementary control measures are urgently needed. The most promising option for control of nematodes is exploitation of genetic variation which is cheap, surprisingly rapid and has proved to be successful in Australia and New Zealand. There are two obstacles to exploiting genetic variation in resistance to nematodes. Many farmers lack expertise in breeding for disease resistance; simplified breeding strategies that utilise markers for disease resistance will help here. Also, there are concerns about sustainability of breeding for resistance to nematodes.A systems biology approach is necessary in order to develop the comprehensive understanding necessary to simplify breeding to ensure that disease control is likely to be sustainable. A systems approach will also help to identify the most suitable combination of approaches under different circumstances. Systems biology combines a variety of disciplines in a quantitative way to achieve a coherent, consistent and comprehensive understanding of host-parasite relationships.This project aims to identify markers for host resistance to nematodes and to enhance our understanding of the host-parasite interaction. We will train a cadre of researchers with the necessary skills to apply quantitative approaches to parasitology and with the essential experience to apply this knowledge to the livestock sector. Fields of science medical and health scienceshealth sciencesparasitologynatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsmedical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceagricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandry Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2010-ITN - Marie-Curie Action: "Initial Training Networks" Call for proposal FP7-PEOPLE-2010-ITN See other projects for this call Funding Scheme MC-ITN - Networks for Initial Training (ITN) Coordinator UNIVERSITY OF GLASGOW EU contribution € 736 605,00 Address UNIVERSITY AVENUE G12 8QQ Glasgow United Kingdom See on map Region Scotland West Central Scotland Glasgow City Activity type Higher or Secondary Education Establishments Administrative Contact Michael James Stear (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSIDAD DE LEON Spain EU contribution € 448 492,00 Address AVENIDA FACULTAD 25 24004 Leon See on map Region Centro (ES) Castilla y León León Activity type Higher or Secondary Education Establishments Administrative Contact Carmen Martinez-Rey (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT France EU contribution € 502 566,00 Address 147 RUE DE L'UNIVERSITE 75007 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Jacques Cabaret (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data AGRIS SARDEGNA Participation ended Italy EU contribution No data Address LOCALITA BONASSAI SS 291 KM 18 6 07100 Sassari See on map Region Isole Sardegna Sassari Activity type Research Organisations Administrative Contact Antonello Carta (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN Ireland EU contribution € 496 512,00 Address BELFIELD 4 Dublin See on map Region Ireland Eastern and Midland Dublin Activity type Higher or Secondary Education Establishments Administrative Contact Torres Sweeney (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data WAGENINGEN UNIVERSITY Netherlands EU contribution € 473 988,00 Address DROEVENDAALSESTEEG 4 6708 PB Wageningen See on map Region Oost-Nederland Gelderland Veluwe Activity type Higher or Secondary Education Establishments Administrative Contact Gerda Bakker (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data BAYERISCHE LANDESANSTALT FUR LANDWIRTSCHAFT Germany EU contribution € 444 030,00 Address VOTTINGER STRASSE 38 85354 Freising See on map Region Bayern Oberbayern Freising Activity type Research Organisations Administrative Contact Johannes Buitkamp (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ReactivLab Ltd United Kingdom EU contribution € 57 330,00 Address The Square, University Avenue 13 G12 8QQ Glasgow See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Peter David Eckersall (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data TOPIGS NORSVIN RESEARCH CENTER BV Netherlands EU contribution € 206 012,00 Address MEERENDONKWEG 25 5216 TZ 'S HERTOGENBOSCH See on map Region Zuid-Nederland Noord-Brabant Noordoost-Noord-Brabant Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Jan Merks (Dr.) Links Contact the organisation Opens in new window Total cost No data