Cel The goal of the AnastomoSEAL project is to develop a biomaterial for tissue engineering for the age-related colorectal cancer (CRC), aiming at increasing the quality of life of patients as well as decreasing the costs of health and long term care. CRC is the second commonest form of cancer in Europe, with an aged-standardized incidence rate of 48 cases per 100’000 in 2008 (data from European Cancer Observatory), mostly affecting elderly people. The most frequent post-operative complication of any bowel resection is the “Anastomotic Leakage” (AL) which occurs up to 21% of cases, after suturing the resected bowel extremities. The project aims to satisfy the widespread clinical need of preventing AL after CRC resection. The objective of the project is the development of a degradable biomaterial, specifically capable of promoting a safe anastomosis during the critical period of tissue healing. We propose to design an innovative biomaterial in form of patch inserted by the surgeon after the anastomotic procedure which wraps around the sutured tissue to reinforce and seal the external part of the intestine, preventing AL and inducing tissue regeneration. The biomaterial will be based on natural polysaccharides alginate and hyaluronic acid (and its butyrate ester), and it will be designed to adhere to the intestinal tissue and to remain in situ for the required time. The goal of the project is to produce a resorbable reinforcing medical device specifically designed to aid rapid sealing and healing of colon-rectal anastomoses. At present, no such specific material for clinical use is available on the market. This device has the potential to become the material of choice for a non-invasive technique and represents an opportunity for the European companies involved in the project to pursue innovation in the biomaterial market. The AnastomoSEAL Consortium involves 2 academic and 4 industrial partners, integrating the RTD chain from material design to pre-clinical testing. Dziedzina nauki medical and health sciencesmedical biotechnologytissue engineeringmedical and health sciencesclinical medicineoncologycolorectal cancernatural sciencesbiological sciencesbiochemistrybiomoleculescarbohydratesengineering and technologyindustrial biotechnologybiomaterials Program(-y) FP7-NMP - Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies Temat(-y) NMP.2011.2.2-2 - Biomaterials for tissue engineering for age-related cancer and sensory organ diseases Zaproszenie do składania wniosków FP7-NMP-2011-SMALL-5 Zobacz inne projekty w ramach tego zaproszenia System finansowania CP-FP - Small or medium-scale focused research project Koordynator UNIVERSITA DEGLI STUDI DI TRIESTE Wkład UE € 770 487,00 Adres PIAZZALE EUROPA 1 34127 Trieste Włochy Zobacz na mapie Region Nord-Est Friuli-Venezia Giulia Trieste Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Paolo Balsini (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (5) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko UNIVERSITEIT MAASTRICHT Niderlandy Wkład UE € 465 731,00 Adres MINDERBROEDERSBERG 4 6200 MD Maastricht Zobacz na mapie Region Zuid-Nederland Limburg (NL) Zuid-Limburg Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Joseph Ih Janssen (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych SIGEA SRL Włochy Wkład UE € 402 482,00 Adres LOCALITA PADRICIANO 99 34012 TRIESTE Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Felice Scoccimarro (Dr.) Linki Kontakt z organizacją Opens in new window Koszt całkowity Brak danych RESCOLL Francja Wkład UE € 445 620,00 Adres ALLEE GEOFFROY SAINT HILAIRE 8 CS 30021 33600 Pessac Zobacz na mapie Region Nouvelle-Aquitaine Aquitaine Gironde Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Konstantin Sipos (Mr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych FMC BIOPOLYMER AS Norwegia Wkład UE € 393 125,00 Adres INDUSTRIVEIEN 33 1337 SANDVIKA Zobacz na mapie Region Norge Oslo og Viken Viken Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Kristen Jester (Ms.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych FEDIUK WLADYSLAW Polska Wkład UE € 222 400,00 Adres Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Wladyslaw Fediuk (Mr.) Linki Kontakt z organizacją Opens in new window Koszt całkowity Brak danych