CORDIS - Resultados de investigaciones de la UE
CORDIS

Triggerable nanomaterials to modulate cell activity

Objetivo

The advent of molecular reprogramming and the associated opportunities for personalised and therapeutic medicine requires the development of novel systems for on-demand delivery of reprogramming factors into cells in order to modulate their activity/identity. Such triggerable systems should allow precise control of the timing, duration, magnitude and spatial release of the reprogramming factors. Furthermore, the system should allow this control even in vivo, using non-invasive means. The present project aims at developing triggerable systems able to release efficiently reprogramming factors on demand. The potential of this technology will be tested in two settings: (i) in the reprogramming of somatic cells in vitro, and (ii) in the improvement of hematopoietic stem cell engraftment in vivo, at the bone marrow. The proposed research involves a team formed by engineers, chemists, biologists and is highly multidisciplinary in nature encompassing elements of engineering, chemistry, system biology, stem cell technology and nanomedicine.

Convocatoria de propuestas

ERC-2012-StG_20111012
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Régimen de financiación

ERC-SG - ERC Starting Grant

Institución de acogida

CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO
Aportación de la UE
€ 1 699 320,00
Dirección
UNIVERSIDADE DE COIMBRA LARGO MARQUES DE POMBAL
3004 517 Coimbra
Portugal

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Región
Continente Centro (PT) Região de Coimbra
Tipo de actividad
Research Organisations
Investigador principal
Lino Da Silva Ferreira (Dr.)
Contacto administrativo
Silvia Sousa (Dr.)
Enlaces
Coste total
Sin datos

Beneficiarios (1)