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Molecular Machines - Design the Nano-Scale Handling of Biological Antetypes the Artificial Mimics

Objetivo

We propose the set-up of a cross-disciplinary research initiative dealing with molecular machines, in particular biological and artificial motors. A close collaboration between chemists known for their expertise in designing functional (bio) molecular motors, biophysicists experienced in dealing with molecular bio machines and physicists with an excellent background in experimental techniques addressing single molecules will advance the basic understanding in this domain to be employed for the steering of molecular engines in the nanometre regime. State-of-the-art theoretical calculations will guide the experimental work and allow for its in-depth interpretation. The objective of the project is to develop new concepts and advance research tools to master the challenge of handling engines-engines at the single-molecule level. We expect that the implementation and integration of the complementary scientific approaches within the consortium will lead to synergetic research achievements. While biological systems are abundant in nature, their fuelling relies mostly on specific chemical reaction schemes and environments. On the other hand, synthetic chemists represented in the consortium have met the challenge of the design of functional artificial molecular motors. Of particular interest is the fact, that de novo designed artificial engines are frequently photo-physically and/or electrically driven, i.e. the corresponding fuelling systems can be integrated in single-molecule experimental set-ups. The long-term vision of our research initiative is, firstly, to merge the advantages of the accessible biological and artificial systems by (self-) assembling of hybrid bioinorganic working devices and, secondly, to rationalize and to operate them on the single-molecule level.

Convocatoria de propuestas

FP6-2002-NMP-1
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Coordinador

FORSCHUNGSZENTRUM KARLSRUHE GMBH
Aportación de la UE
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Dirección
Weberstr. 5
KARLSRUHE
Alemania

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Coste total
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Participantes (9)