Objetivo "Typical treatment for declining heart function or arrhythmias involves expensive surgical implantation of cardiac pacemakers, medical devices which stimulate the heart to beat appropriately.Currently, pacemakers do not operate at optimal conditions, resulting in limited battery life and generic functional settings for patients. Pacemaker batteries have an average life of 5-6 years, leading to frequent necessary replacements and increased mortality from the risks of surgery. Further, the ‘one size fits all’ approach to current pacemaker settings leads to inefficient pacing that can result in inadequate symptom relief and, in some cases, can damage heart muscle by over-pacing the ventricles. We propose to optimize pacemakers through developing novel software tools that generate patient-specific pacemaker device settings, resulting in (1) enhanced battery life, (2) decreased/eliminated replacement surgeries, (3) increased symptom relief, and (4) optimal pacing rates. We estimate this has the potential to save £32m for the NHS in the UK.The project arises from the results obtained in the first phase of the ERC Advanced Grant AdG-246967 VERIWARE (http://www.veriware.org/) which is concerned with sensor-enabled software-controlled devices (so called ‘everyware’), aiming to develop quantitative modelling, verification and synthesis techniques and tools to support the design and validation of their embedded software. The key innovation is the idea of automated synthesis of optimal rates adapted to patient data. While model-based design and validation are employed in the development of pacemakers, parameter settings are largely pre-defined and not changed upon implantation. Our proposal has the potential to revolutionise the design and manufacture of pacemakers." Ámbito científico natural sciencescomputer and information sciencessoftwaresocial sciencessociologydemographymortalitymedical and health sciencesclinical medicinesurgerymedical and health sciencesmedical biotechnologyimplants Programa(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) ERC-OA-2013-PoC - European Research Council ERC Proof of Concept Convocatoria de propuestas ERC-2013-PoC Consulte otros proyectos de esta convocatoria Régimen de financiación CSA-SA(POC) - Supporting action (Proof of Concept) Institución de acogida THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Aportación de la UE € 149 103,00 Dirección WELLINGTON SQUARE UNIVERSITY OFFICES OX1 2JD Oxford Reino Unido Ver en el mapa Región South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Gill Wells (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Beneficiarios (1) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Reino Unido Aportación de la UE € 149 103,00 Dirección WELLINGTON SQUARE UNIVERSITY OFFICES OX1 2JD Oxford Ver en el mapa Región South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Gill Wells (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos
