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Molecular control of self-renewal and lineage specification in thymic epithelial cell progenitors in vivo.

Publications

Editorial: Thymic Epithelial Cells: New Insights Into the Essential Driving Force of T-Cell Differentiation

Author(s): Marita Bosticardo, Izumi Ohigashi, Jennifer E. Cowan, Nuno L. Alves
Published in: Frontiers in Immunology, Issue 12, 2021, ISSN 1664-3224
Publisher: Frontiers in Immunology
DOI: 10.3389/fimmu.2021.744623

The quest for the “HOIL-1” grail of T-cell development

Author(s): Nuno L. Alves, Pedro Ferreirinha
Published in: Cell Death & Differentiation, 2021, ISSN 1350-9047
Publisher: Nature Publishing Group
DOI: 10.1038/s41418-021-00856-2

The Early Postnatal Life: A Dynamic Period in Thymic Epithelial Cell Differentiation

Author(s): Ruben G. R. Pinheiro, Nuno L. Alves
Published in: Frontiers in Immunology, Issue 12, 2021, ISSN 1664-3224
Publisher: Frontiers in Immunology
DOI: 10.3389/fimmu.2021.668528

LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development

Author(s): Pedro M. Rodrigues; Laura G. Sousa; Chiara Perrod; Ana R. Maceiras; Pedro Ferreirinha; Rita Pombinho; Gema Romera-Cárdenas; María Gomez-Lazaro; Meryem Senkara; Jelena Pistolic; Didier Cabanes; Ludger Klein; Paul Saftig; Nuno L. Alves
Published in: Autophagy, Issue 4, 2022, ISSN 1554-8627
Publisher: Landes Bioscience
DOI: 10.6084/m9.figshare.19739032.v1

Setting Up the Perimeter of Tolerance: Insights into mTEC Physiology

Author(s): Pedro M. Rodrigues, Pärt Peterson, Nuno L. Alves
Published in: Trends in Immunology, Issue 39/1, 2018, Page(s) 2-5, ISSN 1471-4906
Publisher: Elsevier BV
DOI: 10.1016/j.it.2017.11.001

Thymic crosstalk restrains the pool of cortical thymic epithelial cells with progenitor properties

Author(s): Catarina Meireles, Ana R. Ribeiro, Rute D. Pinto, Catarina Leitão, Pedro M. Rodrigues, Nuno L. Alves
Published in: European Journal of Immunology, Issue 47/6, 2017, Page(s) 958-969, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201746922

Thymic epithelial cells require p53 to support their long-term function in thymopoiesis in mice

Author(s): Pedro M. Rodrigues, Ana R. Ribeiro, Chiara Perrod, Jonathan J. M. Landry, Leonor Araújo, Isabel Pereira-Castro, Vladimir Benes, Alexandra Moreira, Helena Xavier-Ferreira, Catarina Meireles, Nuno L. Alves
Published in: Blood, Issue 130/4, 2017, Page(s) 478-488, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood-2016-12-758961

Thymus medulla under construction: Time and space oddities

Author(s): Nuno L. Alves, Ana R. Ribeiro
Published in: European Journal of Immunology, Issue 46/4, 2016, Page(s) 829-833, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201646329

A novel role for p53 in self-tolerance

Author(s): Brian M. Larsen, Avinash Bhandoola
Published in: Blood, Issue 130/4, 2017, Page(s) 388-389, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood-2017-06-789115

Intrathymic Deletion of IL-7 Reveals a Contribution of the Bone Marrow to Thymic Rebound Induced by Androgen Blockade

Author(s): Pedro M. Rodrigues, Ana R. Ribeiro, Nicolas Serafini, Catarina Meireles, James P. Di Santo, Nuno L. Alves
Published in: The Journal of Immunology, Issue 200/4, 2018, Page(s) 1389-1398, ISSN 0022-1767
Publisher: American Association of Immunologists
DOI: 10.4049/jimmunol.1701112

Medullary thymic epithelial cells: Deciphering the functional diversity beyond promiscuous gene expression

Author(s): Camila Ribeiro, Nuno L. Alves, Pedro Ferreirinha
Published in: Immunology Letters, Issue 215, 2019, Page(s) 24-27, ISSN 0165-2478
Publisher: Elsevier BV
DOI: 10.1016/j.imlet.2019.01.012

A novel method to identify Post‐Aire stages of medullary thymic epithelial cell differentiation

Author(s): Pedro Ferreirinha, Camila Ribeiro, Junko Morimoto, Jonathan J. M. Landry, Minoru Matsumoto, Catarina Meireles, Andrea J. White, Izumi Ohigashi, Leonor Araújo, Vladimir Benes, Yousuke Takahama, Graham Anderson, Mitsuru Matsumoto, Nuno L. Alves
Published in: European Journal of Immunology, Issue 51/2, 2021, Page(s) 311-318, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202048764

Identification of fibroblast progenitors in the developing mouse thymus

Author(s): Pedro Ferreirinha, Ruben G R Pinheiro, Jonathan J M Landry , Nuno L Alves
Published in: Development, 2022, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.200513

In This issue

Author(s): EJI editorial office
Published in: European Journal of Immunology, Issue 51/2, 2021, Page(s) 267-268, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202170023

Making fibroblasts in the thymus

Author(s): Development
Published in: Development, Issue Development (2022) 149 (10): e149_e1003., 2022, ISSN 1477-9129
Publisher: The Company of Biologists Ltd

Editor's section: IMMUNOLOGY: Tumor suppresor is a thymic booster

Author(s): Editor's section
Published in: Science, Issue 25 Aug 2017: Vol. 357, Issue 6353, pp. 769, 2017, ISSN 1095-9203
Publisher: Science

Deciphering the role of Krüppel-Like Factor 15 in Thymic Epithelial Cell Development and Homeostasis

Author(s): Marcelo Gomes Afonso
Published in: University of Porto Repository, 2020
Publisher: University of Porto Repository

Molecular Insights into the Role of FoxN1 in Thymic Epithelial Cell Development and Function: Generation of a platform for T-cell development through FoxN1-induced cell reprogramming

Author(s): Nuno David
Published in: University Coimbra Repository, 2021
Publisher: Universidade de Coimbra

Unveiling thymic epithelial cell ontogeny: a roadmap to study the microenvironment for T-cell generation and tolerance

Author(s): Ana Rosalina Pereira Ribeiro
Published in: University of Porto Repository, Issue 1, 2016
Publisher: University of Porto

How to keep the thymus in shape: new molecular insights on thymic epitelial cell homeostasis and function

Author(s): Pedro Miguel Mendes Rodrigues
Published in: University of Porto Repository, Issue 1, 2018
Publisher: University of Porto

Refining thymic epithelial cell differentiation: from progenitor cell isolation to the identification of discrete mature lineages

Author(s): Helena Catarina Teixeira Meireles
Published in: University of Porto Repository, Issue 1, 2018
Publisher: University of Porto - ICBAS

Defining novel stages in medullary thymic epithelial cell differentiation: Implications for tolerance induction

Author(s): Maria Camila Trindade Ribeiro
Published in: UP repository, Issue 1, 2019
Publisher: UP

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