Molecular control of self-renewal and lineage specification in thymic epithelial cell progenitors in vivo.

Editorial: Thymic Epithelial Cells: New Insights Into the Essential Driving Force of T-Cell Differentiation

Autori: Marita Bosticardo, Izumi Ohigashi, Jennifer E. Cowan, Nuno L. Alves
Pubblicato in: Frontiers in Immunology, Numero 12, 2021, ISSN 1664-3224
Editore: Frontiers in Immunology
DOI: 10.3389/fimmu.2021.744623

The quest for the “HOIL-1” grail of T-cell development

Autori: Nuno L. Alves, Pedro Ferreirinha
Pubblicato in: Cell Death & Differentiation, 2021, ISSN 1350-9047
Editore: Nature Publishing Group
DOI: 10.1038/s41418-021-00856-2

The Early Postnatal Life: A Dynamic Period in Thymic Epithelial Cell Differentiation

Autori: Ruben G. R. Pinheiro, Nuno L. Alves
Pubblicato in: Frontiers in Immunology, Numero 12, 2021, ISSN 1664-3224
Editore: Frontiers in Immunology
DOI: 10.3389/fimmu.2021.668528

LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development

Autori: Pedro M. Rodrigues; Laura G. Sousa; Chiara Perrod; Ana R. Maceiras; Pedro Ferreirinha; Rita Pombinho; Gema Romera-Cárdenas; María Gomez-Lazaro; Meryem Senkara; Jelena Pistolic; Didier Cabanes; Ludger Klein; Paul Saftig; Nuno L. Alves
Pubblicato in: Autophagy, Numero 4, 2022, ISSN 1554-8627
Editore: Landes Bioscience
DOI: 10.6084/m9.figshare.19739032.v1

Setting Up the Perimeter of Tolerance: Insights into mTEC Physiology

Autori: Pedro M. Rodrigues, Pärt Peterson, Nuno L. Alves
Pubblicato in: Trends in Immunology, Numero 39/1, 2018, Pagina/e 2-5, ISSN 1471-4906
Editore: Elsevier BV
DOI: 10.1016/j.it.2017.11.001

Thymic crosstalk restrains the pool of cortical thymic epithelial cells with progenitor properties

Autori: Catarina Meireles, Ana R. Ribeiro, Rute D. Pinto, Catarina Leitão, Pedro M. Rodrigues, Nuno L. Alves
Pubblicato in: European Journal of Immunology, Numero 47/6, 2017, Pagina/e 958-969, ISSN 0014-2980
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201746922

Thymic epithelial cells require p53 to support their long-term function in thymopoiesis in mice

Autori: Pedro M. Rodrigues, Ana R. Ribeiro, Chiara Perrod, Jonathan J. M. Landry, Leonor Araújo, Isabel Pereira-Castro, Vladimir Benes, Alexandra Moreira, Helena Xavier-Ferreira, Catarina Meireles, Nuno L. Alves
Pubblicato in: Blood, Numero 130/4, 2017, Pagina/e 478-488, ISSN 0006-4971
Editore: American Society of Hematology
DOI: 10.1182/blood-2016-12-758961

Thymus medulla under construction: Time and space oddities

Autori: Nuno L. Alves, Ana R. Ribeiro
Pubblicato in: European Journal of Immunology, Numero 46/4, 2016, Pagina/e 829-833, ISSN 0014-2980
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201646329

A novel role for p53 in self-tolerance

Autori: Brian M. Larsen, Avinash Bhandoola
Pubblicato in: Blood, Numero 130/4, 2017, Pagina/e 388-389, ISSN 0006-4971
Editore: American Society of Hematology
DOI: 10.1182/blood-2017-06-789115

Intrathymic Deletion of IL-7 Reveals a Contribution of the Bone Marrow to Thymic Rebound Induced by Androgen Blockade

Autori: Pedro M. Rodrigues, Ana R. Ribeiro, Nicolas Serafini, Catarina Meireles, James P. Di Santo, Nuno L. Alves
Pubblicato in: The Journal of Immunology, Numero 200/4, 2018, Pagina/e 1389-1398, ISSN 0022-1767
Editore: American Association of Immunologists
DOI: 10.4049/jimmunol.1701112

Medullary thymic epithelial cells: Deciphering the functional diversity beyond promiscuous gene expression

Autori: Camila Ribeiro, Nuno L. Alves, Pedro Ferreirinha
Pubblicato in: Immunology Letters, Numero 215, 2019, Pagina/e 24-27, ISSN 0165-2478
Editore: Elsevier BV
DOI: 10.1016/j.imlet.2019.01.012

A novel method to identify Post‐Aire stages of medullary thymic epithelial cell differentiation

Autori: Pedro Ferreirinha, Camila Ribeiro, Junko Morimoto, Jonathan J. M. Landry, Minoru Matsumoto, Catarina Meireles, Andrea J. White, Izumi Ohigashi, Leonor Araújo, Vladimir Benes, Yousuke Takahama, Graham Anderson, Mitsuru Matsumoto, Nuno L. Alves
Pubblicato in: European Journal of Immunology, Numero 51/2, 2021, Pagina/e 311-318, ISSN 0014-2980
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202048764

Identification of fibroblast progenitors in the developing mouse thymus

Autori: Pedro Ferreirinha, Ruben G R Pinheiro, Jonathan J M Landry , Nuno L Alves
Pubblicato in: Development, 2022, ISSN 0950-1991
Editore: The Company of Biologists Ltd.
DOI: 10.1242/dev.200513

In This issue

Autori: EJI editorial office
Pubblicato in: European Journal of Immunology, Numero 51/2, 2021, Pagina/e 267-268, ISSN 0014-2980
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202170023

Making fibroblasts in the thymus

Autori: Development
Pubblicato in: Development, Numero Development (2022) 149 (10): e149_e1003., 2022, ISSN 1477-9129
Editore: The Company of Biologists Ltd

Editor's section: IMMUNOLOGY: Tumor suppresor is a thymic booster

Autori: Editor's section
Pubblicato in: Science, Numero 25 Aug 2017: Vol. 357, Numero 6353, pp. 769, 2017, ISSN 1095-9203
Editore: Science

Deciphering the role of Krüppel-Like Factor 15 in Thymic Epithelial Cell Development and Homeostasis

Autori: Marcelo Gomes Afonso
Pubblicato in: University of Porto Repository, 2020
Editore: University of Porto Repository

Molecular Insights into the Role of FoxN1 in Thymic Epithelial Cell Development and Function: Generation of a platform for T-cell development through FoxN1-induced cell reprogramming

Autori: Nuno David
Pubblicato in: University Coimbra Repository, 2021
Editore: Universidade de Coimbra

Unveiling thymic epithelial cell ontogeny: a roadmap to study the microenvironment for T-cell generation and tolerance

Autori: Ana Rosalina Pereira Ribeiro
Pubblicato in: University of Porto Repository, Numero 1, 2016
Editore: University of Porto

How to keep the thymus in shape: new molecular insights on thymic epitelial cell homeostasis and function

Autori: Pedro Miguel Mendes Rodrigues
Pubblicato in: University of Porto Repository, Numero 1, 2018
Editore: University of Porto

Refining thymic epithelial cell differentiation: from progenitor cell isolation to the identification of discrete mature lineages

Autori: Helena Catarina Teixeira Meireles
Pubblicato in: University of Porto Repository, Numero 1, 2018
Editore: University of Porto - ICBAS

Defining novel stages in medullary thymic epithelial cell differentiation: Implications for tolerance induction

Autori: Maria Camila Trindade Ribeiro
Pubblicato in: UP repository, Numero 1, 2019
Editore: UP

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