Is your heart aging well? A systems biology approach to characterize cardiac aging from the cell to the body surface

Publikacje

Inhomogeneous Heart Rate Variability Spectral Complexity: A Preliminary Evaluation With Gravitational Stimuli Under Selective Autonomic Blockade

Autorzy: Bolea Juan, Gaetano Valenza, Raquel Bailón, Esther Pueyo, Riccardo Barbieri
Opublikowane w: 2018 Computing in Cardiology Conference (CinC), 2018, ISBN 978-1-7281-0958-9
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2018.312

In silico Electrophysiological Evaluation of Scaffold Geometries for Cardiac Tissue Engineering.

Autorzy: R. Rosales, K. Mountris, M. Doblaré, E. Pueyo
Opublikowane w: Proc. XLVIII International Conference on Computing in Cardiology, 2021, Strona(/y) pp. 1-4
Wydawca: Computing in Cardiology

SK Channel Block and Adrenergic Stimulation Counteract Acetylcholine-Induced Arrhythmogenic Effects in Human Atria

Autorzy: Chiara Celotto, Carlos Sanchez, Konstantinos A. Mountris, Pablo Laguna, Esther Pueyo
Opublikowane w: 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2020, Strona(/y) 2303-2306, ISBN 978-1-7281-1990-8
Wydawca: IEEE
DOI: 10.1109/embc44109.2020.9175886

Potassium Monitoring from Multilead T-wave Morphology Changes during Hemodyalisis: Periodic versus Principal Component Analysis

Autorzy: Flavio Palmieri, Pedro Gomis, José Esteban Ruiz, Dina Ferreira, Alba Martin, Esther Pueyo, Pablo Laguna, Juan Pablo Martínez, Julia Ramírez
Opublikowane w: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2020.199

Adaptation mechanisms of the QT interval during stress test and its dependency with adrenergic stimulation: a simulation study

Autorzy: R.Cebollada, C. Pérez, K. Mountris, P.Laguna, J.P. Martínez, E. Pueyo
Opublikowane w: Proc. XLVIII International Conference on Computing in Cardiology, 2021, Strona(/y) pp. 1-4
Wydawca: Computing in Cardiology

Microgravity Exposure Alters Sympathetic Modulation of Ventricular Repolarization Quantified From the ECG via Periodic Repolarization Dynamics

Autorzy: Saúl Palacios, Enrico Caiani, Juan Pablo Martínez, Esther Pueyo
Opublikowane w: 2018 Computing in Cardiology Conference (CinC), 2018, ISBN 978-1-7281-0958-9
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2018.358

A Novel Paradigm for In Silico Simulation of Cardiac Electrophysiology Through the Mixed Collocation Meshless Petrov-Galerkin Method

Autorzy: Konstantinos Mountris, Carlos Sanchez, Esther Pueyo
Opublikowane w: 2019 Computing in Cardiology Conference (CinC), 2019, ISBN 978-1-7281-6936-1
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2019.382

Relationship between Atrial Oscillatory Acetylcholine Release Pattern and f-wave Frequency Modulation: a Computational and Experimental Study

Autorzy: Chiara Celotto, Carlos Sánchez, Konstantinos Mountris, Mostafa Abdollahpur, Frida Sandberg, Pablo Laguna, Esther Pueyo
Opublikowane w: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2020.303

Sudden Cardiac Death Prediction in Chronic Heart Failure Patients by Periodic Repolarization Dynamics

Autorzy: Saúl Palacios, Iwona Cygankiewicz, Antoni Bayés-de-Luna, Juan Pablo Martínez, Esther Pueyo
Opublikowane w: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2020.209

Influence of the Stimulation Current on the Differences between Cell and Tissue Electrophysiological Simulations

Autorzy: Violeta Monasterio, Esther Pueyo, José Félix Rodríguez-Matas, Jesús Carro
Opublikowane w: 2019 Computing in Cardiology Conference (CinC), 2019, ISBN 978-1-7281-6936-1
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2019.104

Ventilatory Thresholds Estimation Based on ECG-derived Respiratory Rate

Autorzy: D. García, S. Kontaxis, A. Hernández-Vicente, D. Hernando, J. Milagro, E. Pueyo, N. Garatachea, R. Bailón, J. Lazaro
Opublikowane w: Proc. XLVIII International Conference on Computing in Cardiology, 2021, Strona(/y) pp. 1-4
Wydawca: Computing in Cardiology

Weighted Time Warping T-wave Analysis Robust to Delineation Errors: Clinical Implications.

Autorzy: F. Palmieri, P. Gomis, J.E. Ruiz, D. Ferreira, E. Pueyo, J.P. Martínez, P. Laguna, J. Ramírez.
Opublikowane w: Proc. XLVIII International Conference on Computing in Cardiology, 2021, Strona(/y) pp. 1-4
Wydawca: Computing in Cardiology

Changes in QRS and T-wave Loops Subsequent to an Increase in Left Ventricle Globularity as in Intrauterine Growth Restriction: a Simulation Study

Autorzy: Freddy L Bueno-Palomeque, Konstantinos Mountris, Ana Minchole, Nuria Ortigosa, Raquel Bailón, Esther Pueyo, Pablo Laguna
Opublikowane w: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2020.438

Rotor Termination in Cholinergic Paroxysmal Atrial Fibrillation by Small-Calcium-Activated K+ Channels Inhibition and Isoproterenol: a Computational Study

Autorzy: C. Celotto, C. Sánchez, K. Mountris, P. Laguna, E. Pueyo
Opublikowane w: Proc. XLVIII International Conference on Computing in Cardiology, 2021, Strona(/y) pp. 1-4
Wydawca: Computing in Cardiology

Next-generation in-silico Cardiac Electrophysiology through Immersed Grid Meshfree Modelling: Application to Simulation of Myocardial Infarction

Autorzy: Konstantinos Mountris, Esther Pueyo
Opublikowane w: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2020.254

Response of Ventricular Repolarization to Simulated Microgravity Measured by Periodic Repolarization Dynamics Using Phase-Rectified Signal Averaging

Autorzy: Saúl Palacios, Enrico Caiani, Esther Pueyo, Juan Pablo Martínez
Opublikowane w: 2019 Computing in Cardiology Conference (CinC), 2019, ISBN 978-1-7281-6936-1
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2019.169

Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels

Autorzy: Syed Hassaan Ahmed Bukhari, Flavio Palmieri, Dina Ferreira, Mark Potse, Julia Ramırez, Pablo Laguna, Carlos Sanchez, Esther Pueyo
Opublikowane w: 2019 Computing in Cardiology Conference (CinC), 2019, ISBN 978-1-7281-6936-1
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2019.404

Calcium-Activated Potassium Channel Inhibition in Autonomically Stimulated Human Atrial Myocytes.

Autorzy: Chiara Celotto, Carlos Sánchez, Pablo Laguna, Esther Pueyo
Opublikowane w: 2019 Computing in Cardiology Conference (CinC), 2019, ISBN 978-1-7281-6936-1
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2019.334

Improved Methods for Processing Optical Mapping Signals From Human Left Ventricular Tissues at Baseline and Following Adrenergic Stimulation

Autorzy: María Pérez-Zabalza, Emiliano Raúl Diez, Julia Rhyins, Konstantinos Mountris, Jose María Vallejo-Gil, Pedro Carlos Fresneda-Roldán, Javier Fañanás-Mastral, Marta Matamala-Adell, Fernando Sorribas-Berjón, Manuel Vázquez-Sancho, Carlos Ballester-Cuenca, Margarita Segovia-Roldán, Aida Oliván-Viguera, Esther Pueyo
Opublikowane w: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2020.427

Characterization of impaired repolarization by quantification of the QT delay in response to heart rate changes from stress test recordings

Autorzy: Cristina Perez, Esther Pueyo, Juan Pablo Martinez, Pablo Laguna
Opublikowane w: 2020 11th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO), 2020, Strona(/y) 1-2, ISBN 978-1-7281-5751-1
Wydawca: IEEE
DOI: 10.1109/esgco49734.2020.9158186

Quantification of T-wave Morphological Variability Using Time-warping Methods

Autorzy: Julia Ramírez, Michele Orini, Esther Pueyo, Pablo Laguna
Opublikowane w: IFMBE Proceedings, Numer 65, 2017, Strona(/y) 478-481, ISBN 978-981-10-5121-0
Wydawca: Springer Singapore
DOI: 10.1007/978-981-10-5122-7_120

An Index for T:wave Pointwise Amplitude Variability Quantification

Autorzy: Julia Ramirez, Michele Orini, J. Derek Tucker, Esther Pueyo, Pablo Laguna
Opublikowane w: 2016 Computing in Cardiology Conference (CinC), Numer 43, 2016, ISBN 978-1-5090-0895-7
Wydawca: Computing in Cardiology
DOI: 10.22489/CinC.2016.016-137

T-wave Morphology Restitution Dependency with Heart Rate Range and Its Association with Sudden Cardiac Death in Chronic Heart Failure

Autorzy: Julia Ram�rez, Michele Orini, Esther Pueyo, Pablo Laguna
Opublikowane w: 2017 Computing in Cardiology Conference (CinC), Numer 44, 2017, ISBN 978-1-5386-6630-2
Wydawca: Computing in Cardiology
DOI: 10.22489/CinC.2017.221-009

Comparison of ECG T-wave Duration and Morphology Restitution Markers for Sudden Cardiac Death Prediction in Chronic Heart Failure

Identification of Parameters describing Phenomenological Cardiac Action Potential Models using Sigma-point Methods

Autorzy: Jesus Fernandez-Bes, David Adolfo Sampedro-Puente, Esther Pueyo
Opublikowane w: 2017 Computing in Cardiology Conference (CinC), Numer 44, 2017, ISBN 978-1-5386-6630-2
Wydawca: Computing in Cardiology
DOI: 10.22489/CinC.2017.060-109

Differential Responses to Beta-Adrenergic Stimulation in the Long QT Syndrome Type 1: Characterization and Mechanisms

Autorzy: David Adolfo Sampedro-Puente, Jesus Fernandez-Bes, Esther Pueyo
Opublikowane w: 2017 Computing in Cardiology Conference (CinC), Numer 44, 2017, ISBN 978-1-5386-6630-2
Wydawca: Computing in Cardiology
DOI: 10.22489/CinC.2017.250-453

Age-Associated Changes in Myocardial Fibrosis Amount and Distribution Quantified from Nonlinear Optical Microscopy Images

Autorzy: M. Pérez, L. García, K. Mountris, L. Ordovás, E. Pueyo
Opublikowane w: Proc. XLVIII International Conference on Computing in Cardiology, 2021, Strona(/y) pp. 1-4
Wydawca: Computing in Cardiology

QRS Slopes for Potassium and Calcium Monitoring in End-Stage Renal Disease Patients

Autorzy: H.A. Bukhari, P. Laguna, M. Potse, C. Sánchez, E. Pueyo.
Opublikowane w: Proc. XLVIII International Conference on Computing in Cardiology, 2021, Strona(/y) pp. 1-4
Wydawca: Computing in Cardiology

T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients

Autorzy: Flavio Palmieri, Pedro Gomis, José Esteban Ruiz, Beatriz Bergasa, Ferreira Dina, Alba Martin, Syed Hassaan Ahamed, Esther Pueyo, Juan Pablo Martínez, Julia Ramírez, Pablo Laguna
Opublikowane w: 2019 Computing in Cardiology Conference (CinC), 2019, Strona(/y) pp. 1-4, ISBN 978-1-7281-6936-1
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2019.109

In Silico Characterization of Repolarization Duration and Variability in the LQT1 Syndrome Under β-Adrenergic Stimulation

Autorzy: David Adolfo Sampedro-Puente, Fabien Raphel, Jesus Fernandez-Bes, Pablo Laguna, Damiano Lombardi, Esther Pueyo
Opublikowane w: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2020.430

Analysis of T Wave Nonlinear Dynamics for Serum Potassium Monitoring in End-Stage Renal Disease Patients

Autorzy: SABARATHINAM SRINIVASAN, Syed Hassaan Ahmed Bukhari, Pablo Laguna, Carlos Sánchez, Esther Pueyo
Opublikowane w: 2020 Computing in Cardiology Conference (CinC), 2020, ISBN 978-1-7281-7382-5
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2020.461

Assessing a Warping Methodology for the Identification of Increased Cardiovascular Risk Based on the HR Profile Morphology

Autorzy: Julia Ramírez, Stefan van Duijvenboden, Pablo Laguna, Esther Pueyo, Andrew Tinker, Pier Lambiase, Patricia Munroe, Michele Orini
Opublikowane w: 2018 Computing in Cardiology Conference (CinC), 2018, ISBN 978-1-7281-0958-9
Wydawca: Computing in Cardiology
DOI: 10.22489/cinc.2018.039

KCa3.1 Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility

Autorzy: Marta Sofía Valero, Mariano Ramón-Gimenez, Javier Lozano-Gerona, Pablo Delgado-Wicke, Pilar Calmarza, Aida Oliván-Viguera, Víctor López, Ángel-Luis Garcia-Otín, Salvador Valero, Esther Pueyo, Kirk L. Hamilton, Hiroto Miura, Ralf Köhler
Opublikowane w: International Journal of Molecular Sciences, Numer 20/5, 2019, Strona(/y) 1193, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20051193

Automatic Quantification of Cardiomyocyte Dimensions and Connexin 43 Lateralization in Fluorescence Images

Autorzy: Antoni Oliver-Gelabert, Laura García-Mendívil, José María Vallejo-Gil, Pedro Carlos Fresneda-Roldán, Katarína Andelová, Javier Fañanás-Mastral, Manuel Vázquez-Sancho, Marta Matamala-Adell, Fernando Sorribas-Berjón, Carlos Ballester-Cuenca, Narcisa Tribulova, Laura Ordovás, Emiliano Raúl Diez, Esther Pueyo
Opublikowane w: Biomolecules, Numer 10/9, 2020, Strona(/y) 1334, ISSN 2218-273X
Wydawca: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/biom10091334

Characterization of T Wave Amplitude, Duration and Morphology Changes During Hemodialysis: Relationship With Serum Electrolyte Levels and Heart Rate

Autorzy: Hassaan A. Bukhari, Flavio Palmieri, Julia Ramirez, Pablo Laguna, Jose Esteban Ruiz, Dina Ferreira, Mark Potse, Carlos Sanchez, Esther Pueyo
Opublikowane w: IEEE Transactions on Biomedical Engineering, Numer 68/8, 2021, Strona(/y) 2467-2478, ISSN 0018-9294
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2020.3043844

Nonlinear T-Wave Time Warping-Based Sensing Model for Non-Invasive Personalised Blood Potassium Monitoring in Hemodialysis Patients: A Pilot Study

Autorzy: Flavio Palmieri, Pedro Gomis, José Esteban Ruiz, Dina Ferreira, Alba Martín-Yebra, Esther Pueyo, Juan Pablo Martínez, Julia Ramírez, Pablo Laguna
Opublikowane w: Sensors, Numer 21/8, 2021, Strona(/y) 2710, ISSN 1424-8220
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s21082710

Long-Term Microgravity Exposure Increases ECG Repolarization Instability Manifested by Low-Frequency Oscillations of T-Wave Vector

Autorzy: Saúl Palacios, Enrico G. Caiani, Federica Landreani, Juan Pablo Martínez, Esther Pueyo
Opublikowane w: Frontiers in Physiology, Numer 10, 2019, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2019.01510

Pulse Rate and Transit Time Analysis to Predict Hypotension Events After Spinal Anesthesia During Programmed Cesarean Labor

Autorzy: Juan Bolea, Jesús Lázaro, Eduardo Gil, Eva Rovira, José M. Remartínez, Pablo Laguna, Esther Pueyo, Augusto Navarro, Raquel Bailón
Opublikowane w: Annals of Biomedical Engineering, Numer 45/9, 2017, Strona(/y) 2253-2263, ISSN 0090-6964
Wydawca: Kluwer Academic Publishers
DOI: 10.1007/s10439-017-1864-y

Emerging evidence for a mechanistic link between low-frequency oscillation of ventricular repolarization measured from the electrocardiogram T-wave vector and arrhythmia

Autorzy: Peter Taggart, Esther Pueyo, Stefan van Duijvenboden, Bradley Porter, Martin Bishop, David A Sampedro-Puente, M Orini, B Hanson, Christopher A Rinaldi, Jaswinder S Gill, Pier Lambiase
Opublikowane w: EP Europace, Numer 23/9, 2021, Strona(/y) 1350-1358, ISSN 1099-5129
Wydawca: Oxford University Press
DOI: 10.1093/europace/euab009

Characterization of Spatio-Temporal Cardiac Action Potential Variability at Baseline and Under $\beta$-Adrenergic Stimulation by Combined Unscented Kalman Filter and Double Greedy Dimension Reduction

Autorzy: David Adolfo Sampedro-Puente, Fabien Raphel, Jesus Fernandez-Bes, Pablo Laguna, Damiano Lombardi, Esther Pueyo
Opublikowane w: IEEE Journal of Biomedical and Health Informatics, Numer 25/1, 2021, Strona(/y) 276-288, ISSN 2168-2194
Wydawca: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/jbhi.2020.2984647

ECG Ventricular Repolarization Dynamics during Exercise: Temporal Profile, Relation to Heart Rate Variability and Effects of Age and Physical Health

Autorzy: Adrián Hernández-Vicente, David Hernando, Germán Vicente-Rodríguez, Raquel Bailón, Nuria Garatachea, Esther Pueyo
Opublikowane w: International Journal of Environmental Research and Public Health, Numer 18/18, 2021, Strona(/y) 9497, ISSN 1660-4601
Wydawca: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/ijerph18189497

Editorial: Perspectives of Antiarrhythmic Drug Therapy: Disappointing Past, Current Efforts, and Faint Hopes

Autorzy: Péter P. Nánási, Esther Pueyo, László Virág
Opublikowane w: Frontiers in Pharmacology, Numer 11, 2020, ISSN 1663-9812
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fphar.2020.01116

Heart Rate Variability and Exceptional Longevity

Autorzy: Adrián Hernández-Vicente, David Hernando, Alejandro Santos-Lozano, Gabriel Rodríguez-Romo, Germán Vicente-Rodríguez, Esther Pueyo, Raquel Bailón, Nuria Garatachea
Opublikowane w: Frontiers in Physiology, Numer 11, 2020, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.566399

Monitoring blood potassium concentration in hemodialysis patients by quantifying T-wave morphology dynamics

Autorzy: Flavio Palmieri, Pedro Gomis, Dina Ferreira, José Esteban Ruiz, Beatriz Bergasa, Alba Martín-Yebra, Hassaan A. Bukhari, Esther Pueyo, Juan Pablo Martínez, Julia Ramírez, Pablo Laguna
Opublikowane w: Scientific Reports, Numer 11/1, 2021, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-021-82935-5

Time Course of Low-Frequency Oscillatory Behavior in Human Ventricular Repolarization Following Enhanced Sympathetic Activity and Relation to Arrhythmogenesis

Autorzy: David Adolfo Sampedro-Puente, Jesus Fernandez-Bes, Norbert Szentandrássy, Péter Nánási, Peter Taggart, Esther Pueyo
Opublikowane w: Frontiers in Physiology, Numer 10, 2020, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2019.01547

Estimation of the second ventilatory threshold through ventricular repolarization profile analysis

Autorzy: Javier Milagro, Adrián Hernández‐Vicente, David Hernando, José A. Casajús, Nuria Garatachea, Raquel Bailón, Esther Pueyo
Opublikowane w: Scandinavian Journal of Medicine & Science in Sports, Numer 31/2, 2021, Strona(/y) 339-349, ISSN 0905-7188
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/sms.13849

Cardiac computational modelling

Autorzy: Jean R. Bragard, Oscar Camara, Blas Echebarria, Luca Gerardo Giorda, Esther Pueyo, Javier Saiz, Rafael Sebastián, Eduardo Soudah, Mariano Vázquez
Opublikowane w: Revista Española de Cardiología (English Edition), Numer 74/1, 2021, Strona(/y) 65-71, ISSN 1885-5857
Wydawca: Elsevier
DOI: 10.1016/j.rec.2020.05.024

Reperfusion Arrhythmias Increase after Superior Cervical Ganglionectomy Due to Conduction Disorders and Changes in Repolarization

Autorzy: Natalia Jorgelina Prado, Estela Maris Muñoz, Luz Estefanía Farias Altamirano, Francisco Aguiar, Amira Zulma Ponce Zumino, Francisco Javier Sánchez, Roberto Miguel Miatello, Esther Pueyo, Emiliano Raúl Diez
Opublikowane w: International Journal of Molecular Sciences, Numer 21/5, 2020, Strona(/y) 1804, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21051804

ECG-based monitoring of blood potassium concentration: Periodic versus principal component as lead transformation for biomarker robustness

Autorzy: Flavio Palmieri, Pedro Gomis, José Esteban Ruiz, Dina Ferreira, Alba Martín-Yebra, Esther Pueyo, Juan Pablo Martínez, Julia Ramírez, Pablo Laguna
Opublikowane w: Biomedical Signal Processing and Control, Numer 68, 2021, Strona(/y) 102719, ISSN 1746-8094
Wydawca: Elsevier BV
DOI: 10.1016/j.bspc.2021.102719

Minimally invasive system to reliably characterize ventricular electrophysiology from living donors

Autorzy: Aida Oliván-Viguera, María Pérez-Zabalza, Laura García-Mendívil, Konstantinos A. Mountris, Sofía Orós-Rodrigo, Estel Ramos-Marquès, José María Vallejo-Gil, Pedro Carlos Fresneda-Roldán, Javier Fañanás-Mastral, Manuel Vázquez-Sancho, Marta Matamala-Adell, Fernando Sorribas-Berjón, Javier André Bellido-Morales, Francisco Javier Mancebón-Sierra, Alexánder Sebastián Vaca-Núñez, Ca
Opublikowane w: Scientific Reports, Numer 10/1, 2020, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-77076-0

Data-Driven Identification of Stochastic Model Parameters and State Variables: Application to the Study of Cardiac Beat-to-Beat Variability

Autorzy: David Adolfo Sampedro-Puente, Jesus Fernandez-Bes, Laszlo Virag, Andras Varro, Esther Pueyo
Opublikowane w: IEEE Journal of Biomedical and Health Informatics, Numer 24/3, 2020, Strona(/y) 693-704, ISSN 2168-2194
Wydawca: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/jbhi.2019.2921881

A dual adaptive explicit time integration algorithm for efficiently solving the cardiac monodomain equation

Autorzy: Konstantinos A. Mountris, Esther Pueyo
Opublikowane w: International Journal for Numerical Methods in Biomedical Engineering, Numer 37/7, 2021, ISSN 2040-7939
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/cnm.3461

Bifurcations and Slow-Fast Analysis in a Cardiac Cell Model for Investigation of Early Afterdepolarizations

Autorzy: Roberto Barrio, M. Angeles Martínez, Lucía Pérez, Esther Pueyo
Opublikowane w: Mathematics, Numer 8/6, 2020, Strona(/y) 880, ISSN 2227-7390
Wydawca: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/math8060880

The ‘Digital Twin’ to enable the vision of precision cardiology

Autorzy: Jorge Corral-Acero, Francesca Margara, Maciej Marciniak, Cristobal Rodero, Filip Loncaric, Yingjing Feng, Andrew Gilbert, Joao F Fernandes, Hassaan A Bukhari, Ali Wajdan, Manuel Villegas Martinez, Mariana Sousa Santos, Mehrdad Shamohammdi, Hongxing Luo, Philip Westphal, Paul Leeson, Paolo DiAchille, Viatcheslav Gurev, Manuel Mayr, Liesbet Geris, Pras Pathmanathan, Tina Morrison, Richard Cornelusse
Opublikowane w: European Heart Journal, Numer 41/48, 2020, Strona(/y) 4556-4564, ISSN 0195-668X
Wydawca: Oxford University Press
DOI: 10.1093/eurheartj/ehaa159

Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes

Autorzy: Aida Olivan-Viguera, Angel Luis Garcia-Otin, Javier Lozano-Gerona, Edgar Abarca-Lachen, Ana J. Garcia-Malinis, Kirk L. Hamilton, Yolanda Gilaberte, Esther Pueyo, Ralf Köhler
Opublikowane w: PLOS ONE, Numer 13/1, 2018, Strona(/y) e0190307, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0190307

Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model

Autorzy: Julia Ramírez, Michele Orini, Ana Mincholé, Violeta Monasterio, Iwona Cygankiewicz, Antonio Bayés de Luna, Juan Pablo Martínez, Pablo Laguna, Esther Pueyo
Opublikowane w: PLOS ONE, Numer 12/10, 2017, Strona(/y) e0186152, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0186152

Atrial Fibrillation Dynamics and Ionic Block Effects in Six Heterogeneous Human 3D Virtual Atria with Distinct Repolarization Dynamics

Autorzy: Carlos Sánchez, Alfonso Bueno-Orovio, Esther Pueyo, Blanca Rodríguez
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 5, 2017, ISSN 2296-4185
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fbioe.2017.00029

A Time-Varying Non-Parametric Methodology for Assessing Changes in QT Variability Unrelated to Heart Rate Variability

Autorzy: michele orini, Esther Pueyo, Pablo Laguna, Raquel Bailon
Opublikowane w: IEEE Transactions on Biomedical Engineering, 2017, Strona(/y) 1-1, ISSN 0018-9294
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/TBME.2017.2758925

Variability of Ventricular Repolarization Dispersion Quantified by Time-Warping the Morphology of the T-Waves

Autorzy: Julia Ramirez, Michele Orini, J. Derek Tucker, Esther Pueyo, Pablo Laguna
Opublikowane w: IEEE Transactions on Biomedical Engineering, Numer 64/7, 2017, Strona(/y) 1619-1630, ISSN 0018-9294
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/TBME.2016.2614899

Limitations in electrophysiological model development and validation caused by differences between simulations and experimental protocols

Autorzy: Jesús Carro, José F. Rodríguez-Matas, Violeta Monasterio, Esther Pueyo
Opublikowane w: Progress in Biophysics and Molecular Biology, Numer 129, 2017, Strona(/y) 53-64, ISSN 0079-6107
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.pbiomolbio.2016.11.006

T‐Wave Morphology Restitution Predicts Sudden Cardiac Death in Patients With Chronic Heart Failure

Autorzy: Julia Ramírez, Michele Orini, Ana Mincholé, Violeta Monasterio, Iwona Cygankiewicz, Antonio Bayés de Luna, Juan Pablo Martínez, Esther Pueyo, Pablo Laguna
Opublikowane w: Journal of the American Heart Association, Numer 6/5, 2017, Strona(/y) e005310, ISSN 2047-9980
Wydawca: Wiley-Blackwell
DOI: 10.1161/JAHA.116.005310

Influence of Heart Rate in Non-linear HRV Indices as a Sampling Rate Effect Evaluated on Supine and Standing

Autorzy: Juan Bolea, Esther Pueyo, Michele Orini, Raquel Bailón
Opublikowane w: Frontiers in Physiology, Numer 7, 2016, Strona(/y) 00501(12pp), ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2016.00501

Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block

Autorzy: Jose Vicente, Lars Johannesen, Meisam Hosseini, Jay W. Mason, Philip T. Sager, Esther Pueyo, David G. Strauss
Opublikowane w: PLOS ONE, Numer 11/12, 2016, Strona(/y) e0163619, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0163619

Interactive effect of beta-adrenergic stimulation and mechanical stretch on low-frequency oscillations of ventricular action potential duration in humans

Autorzy: Esther Pueyo, Michele Orini, José F. Rodríguez, Peter Taggart
Opublikowane w: Journal of Molecular and Cellular Cardiology, Numer 97, 2016, Strona(/y) 93-105, ISSN 0022-2828
Wydawca: Academic Press
DOI: 10.1016/j.yjmcc.2016.05.003

Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition

Autorzy: E. Pueyo, C. E. Dangerfield, O. J. Britton, L. Virág, K. Kistamás, N. Szentandrássy, N. Jost, A. Varró, P. P. Nánási, K. Burrage, B. Rodríguez
Opublikowane w: PLOS ONE, Numer 11/3, 2016, Strona(/y) e0151461, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0151461

Techniques for Ventricular Repolarization Instability Assessment From the ECG

Autorzy: Pablo Laguna, Juan Pablo Martinez Cortes, Esther Pueyo
Opublikowane w: Proceedings of the IEEE, Numer 104/2, 2016, Strona(/y) 392-415, ISSN 0018-9219
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/JPROC.2015.2500501

A response surface optimization approach to adjust ionic current conductances of cardiac electrophysiological models. Application to the study of potassium level changes

Autorzy: Jesús Carro, Esther Pueyo, José F. Rodríguez Matas
Opublikowane w: PLOS ONE, Numer 13/10, 2018, Strona(/y) e0204411, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0204411

On the Standardization of Approximate Entropy: Multidimensional Approximate Entropy Index Evaluated on Short-Term HRV Time Series

Autorzy: Juan Bolea, Raquel Bailón, Esther Pueyo
Opublikowane w: Complexity, Numer 2018, 2018, Strona(/y) 1-15, ISSN 1076-2787
Wydawca: John Wiley & Sons Inc.
DOI: 10.1155/2018/4953273

A Methodology to Improve Human Ventricular Models for the Investigation of Cardiac Arrhythmias

Autorzy: Jesús Carro, José F Rodríguez-Matas, Esther Pueyo
Opublikowane w: Biophysical Journal, Numer 112/3, 2017, Strona(/y) 403a, ISSN 0006-3495
Wydawca: Biophysical Society
DOI: 10.1016/j.bpj.2016.11.2183

Getting to the Heart of Safety Pharmacology

Autorzy: Eleonora Grandi, Stefano Morotti, Esther Pueyo, Blanca Rodríguez
Opublikowane w: Frontiers in Physiology, 2018, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2018.00678

Correction: Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition

Autorzy: E. Pueyo, C. E. Dangerfield, O. J. Britton, L. Virág, K. Kistamás, N. Szentandrássy, N. Jost, A. Varró, P. P. Nánási, K. Burrage, B. Rodríguez
Opublikowane w: PLOS ONE, Numer 13/5, 2018, Strona(/y) e0197871, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0197871

Correction: Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block

Autorzy: Jose Vicente, Lars Johannesen, Meisam Hosseini, Jay W. Mason, Philip T. Sager, Esther Pueyo, David G. Strauss
Opublikowane w: PLOS ONE, Numer 13/5, 2018, Strona(/y) e0197952, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0197952

Corrigendum: Influence of Heart Rate in Non-linear HRV Indices as a Sampling Rate Effect Evaluated on Supine and Standing

Autorzy: Juan Bolea, Esther Pueyo, Michele Orini, Raquel Bailón
Opublikowane w: Frontiers in Physiology, Numer 9, 2018, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2018.00620

Corrigendum to “Limitations in electrophysiological model development and validation caused by differences between simulations and experimental protocols” [Prog. Biophys. Mol. Biol. 129 (2017) 53–64]

Autorzy: Jesús Carro, José F. Rodríguez-Matas, Violeta Monasterio, Esther Pueyo
Opublikowane w: Progress in Biophysics and Molecular Biology, 2018, ISSN 0079-6107
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.pbiomolbio.2018.11.001

Correction: T‐Wave Morphology Restitution Predicts Sudden Cardiac Death in Patients With Chronic Heart Failure

Corrigendum to “Interactive effect of beta-adrenergic stimulation and mechanical stretch on low-frequency oscillations of ventricular action potential duration in humans” [J. Mol. Cell. Cardiol. 97 (2016) 93–105]

Autorzy: Esther Pueyo, Michele Orini, José F. Rodríguez, Peter Taggart
Opublikowane w: Journal of Molecular and Cellular Cardiology, Numer 121, 2018, Strona(/y) 305, ISSN 0022-2828
Wydawca: Academic Press
DOI: 10.1016/j.yjmcc.2018.05.006

Conditional KCa3.1-Transgene Induction in Murine Skin Produces Pruritic Eczematous Dermatitis With Severe Epidermal Hyperplasia and Hyperkeratosis

Autorzy: Javier Lozano-Gerona; Aida Oliván-Viguera; Pablo Delgado-Wicke; Vikrant Singh; Brandon M. Brown; Elena Tapia-Casellas; Esther Pueyo; Marta Sofía Valero; Ángel Luis García-Otín; Pilar Giraldo; Edgar Abarca-Lachen; Joaquín C. Surra; Jesús Osada; Kirk L. Hamilton; Siba P. Raychaudhuri; Miguel Marigil; Angeles Juarranz; Heike Wulff; Hiroto Miura; Yolanda Gilaberte; Ralf Köhler
Opublikowane w: PLoS ONE, Numer 1, 2020, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1101/759274

Location of Parasympathetic Innervation Regions From Electrograms to Guide Atrial Fibrillation Ablation Therapy: An in silico Modeling Study

Autorzy: Chiara Celotto, Carlos Sánchez, Konstantinos A. Mountris, Pablo Laguna, Esther Pueyo
Opublikowane w: Frontiers in Physiology, Numer 12, 2021, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.674197

Mechanisms Underlying Interactions Between Low-Frequency Oscillations and Beat-to-Beat Variability of Celullar Ventricular Repolarization in Response to Sympathetic Stimulation: Implications for Arrhythmogenesis

Autorzy: David Adolfo Sampedro-Puente, Jesus Fernandez-Bes, Bradley Porter, Stefan van Duijvenboden, Peter Taggart, Esther Pueyo
Opublikowane w: Frontiers in Physiology, Numer 10, 2019, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2019.00916

Excitable dynamics in neural and cardiac systems

Autorzy: Roberto Barrio, Stephen Coombes, Mathieu Desroches, Flavio Fenton, Stefan Luther, Esther Pueyo
Opublikowane w: Communications in Nonlinear Science and Numerical Simulation, Numer 86, 2020, Strona(/y) 105275, ISSN 1007-5704
Wydawca: Elsevier BV
DOI: 10.1016/j.cnsns.2020.105275

Chronological and biological aging of the human left ventricular myocardium: Analysis of microRNAs contribution

Autorzy: Estel Ramos‐Marquès, Laura García‐Mendívil, María Pérez‐Zabalza, Hazel Santander‐Badules, Sabarathinam Srinivasan, Juan Carlos Oliveros, Rafael Torres‐Pérez, Alberto Cebollada, José María Vallejo‐Gil, Pedro Carlos Fresneda‐Roldán, Javier Fañanás‐Mastral, Manuel Vázquez‐Sancho, Marta Matamala‐Adell, Juan Fernando Sorribas‐Berjón, Javier André Bellido‑Morales, F
Opublikowane w: Aging Cell, Numer 20/7, 2021, ISSN 1474-9718
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/acel.13383

QT variability unrelated to RR variability during stress testing for identification of coronary artery disease

Autorzy: Marta González del Castillo, David Hernando, Michele Orini, Pablo Laguna, Jari Viik, Raquel Bailón, Esther Pueyo
Opublikowane w: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, Numer 379/2212, 2021, ISSN 1364-503X
Wydawca: Royal Society of London
DOI: 10.1098/rsta.2020.0261

Ischemia detection from morphological QRS angle changes

Autorzy: Daniel Romero, Juan Pablo Martínez, Pablo Laguna, Esther Pueyo
Opublikowane w: Physiological Measurement, Numer 37/7, 2016, Strona(/y) 1004-1023, ISSN 0967-3334
Wydawca: Institute of Physics Publishing
DOI: 10.1088/0967-3334/37/7/1004

The radial point interpolation mixed collocation method for the solution of transient diffusion problems

Autorzy: Konstantinos A. Mountris, Esther Pueyo
Opublikowane w: Engineering Analysis with Boundary Elements, Numer 121, 2020, Strona(/y) 207-216, ISSN 0955-7997
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.enganabound.2020.10.005

Cell‐based maximum entropy approximants for three‐dimensional domains: Application in large strain elastodynamics using the meshless total Lagrangian explicit dynamics method

Autorzy: Konstantinos A. Mountris, George C. Bourantas, Daniel Millán, Grand R. Joldes, Karol Miller, Esther Pueyo, Adam Wittek
Opublikowane w: International Journal for Numerical Methods in Engineering, Numer 121/3, 2020, Strona(/y) 477-491, ISSN 0029-5981
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/nme.6218

Complex Interaction Between Low-Frequency APD Oscillations and Beat-to-Beat APD Variability in Humans Is Governed by the Sympathetic Nervous System

Autorzy: Stefan Van Duijvenboden, Bradley Porter, Esther Pueyo, David Adolfo Sampedro-Puente, Jesus Fernandez-Bes, Baldeep Sidhu, Justin Gould, Michele Orini, Martin J. Bishop, Ben Hanson, Pier Lambiase, Reza Razavi, Christopher A. Rinaldi, Jaswinder S. Gill, Peter Taggart
Opublikowane w: Frontiers in Physiology, Numer 10, 2020, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2019.01582

Dynamical analysis of early afterdepolarization patterns in a biophysically detailed cardiac model

Autorzy: Roberto Barrio, M. Ángeles Martínez, Esther Pueyo, Sergio Serrano
Opublikowane w: Chaos: An Interdisciplinary Journal of Nonlinear Science, Numer 31/7, 2021, Strona(/y) 073137, ISSN 1054-1500
Wydawca: American Institute of Physics
DOI: 10.1063/5.0055965

Atrial Dyssynchrony Measured by Strain Echocardiography as a Marker of Proarrhythmic Remodeling and Oxidative Stress in Cardiac Surgery Patients

Autorzy: Francisco J. Sánchez, Valeria A. Gonzalez, Martin Farrando, Ariel O. Baigorria Jayat, Margarita Segovia-Roldan, Laura García-Mendívil, Laura Ordovás, Natalia J. Prado, Esther Pueyo, Emiliano R. Diez
Opublikowane w: Oxidative Medicine and Cellular Longevity, Numer 2020, 2020, Strona(/y) 1-14, ISSN 1942-0900
Wydawca: Landes Bioscience
DOI: 10.1155/2020/8895078

Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics

Autorzy: Julia Ramírez, Stefan van Duijvenboden, Nay Aung, Pablo Laguna, Esther Pueyo, Andrew Tinker, Pier D. Lambiase, Michele Orini, Patricia B. Munroe
Opublikowane w: Circulation: Arrhythmia and Electrophysiology, Numer 12/10, 2019, ISSN 1941-3149
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circep.119.007549

Melatonin to Rescue the Aged Heart: Antiarrhythmic and Antioxidant Benefits

Autorzy: Margarita Segovia-Roldan, Emiliano Raúl Diez, Esther Pueyo
Opublikowane w: Oxidative Medicine and Cellular Longevity, Numer 2021, 2021, Strona(/y) 1-18, ISSN 1942-0900
Wydawca: Landes Bioscience
DOI: 10.1155/2021/8876792

Periodic repolarization dynamics as predictor of risk for sudden cardiac death in chronic heart failure patients

Autorzy: Saúl Palacios, Iwona Cygankiewicz, Antoni Bayés de Luna, Esther Pueyo, Juan Pablo Martínez
Opublikowane w: Scientific Reports, Numer 11/1, 2021, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-021-99861-1

Validity of the Polar H7 Heart Rate Sensor for Heart Rate Variability Analysis during Exercise in Different Age, Body Composition and Fitness Level Groups

Autorzy: Adrián Hernández-Vicente, David Hernando, Jorge Marín-Puyalto, Germán Vicente-Rodríguez, Nuria Garatachea, Esther Pueyo, Raquel Bailón
Opublikowane w: Sensors, Numer 21/3, 2021, Strona(/y) 902, ISSN 1424-8220
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s21030902

Prediction of Cardiac Death Risk by Analysis of Ventricular Repolarization Restitution from the Electrocardiogram Signal

Autorzy: Julia Ramírez, Esther Pueyo (Supervisor), Pablo Laguna (Supervisor)
Opublikowane w: Doctoral Thesis, 2017, ISSN 2254-7606
Wydawca: University of Zaragoza

Novel electrocardiographic biomarkers for proarrhythmic assessment of drugs

Autorzy: José Vicente Ruiz, David G. Strauss (Supervisor), Esther Pueyo (Supervisor)
Opublikowane w: Doctoral Thesis, 2016
Wydawca: University of Zaragoza

Time-frequency analysis of heart rate variability for characterization of autonomic impairments

Autorzy: Juan Bolea, Raquel Bailón (Supervisor), Esther Pueyo (Supervisor)
Opublikowane w: Doctoral Thesis, 2018
Wydawca: University of Zaragoza

New methodologies for the development and validation of cardiac electrophysiological models

Autorzy: Jesús Carro, José F. Rodríguez (Supervisor), Esther Pueyo (Supervisor)
Opublikowane w: Doctoral Thesis, 2018
Wydawca: University of Zaragoza

Theoretical analysis of the effects of the Autonomic Nervous System on human cardiac electrophysiology and its relation to arrhythmic risk

Autorzy: David Sampedro, Esther Pueyo (Supervisor)
Opublikowane w: Doctoral Thesis, 2019
Wydawca: University of Zaragoza

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