Functions of the X chromosome in the mammalian germ line

Publicaciones

CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes

Autores: Charlotte Douglas, Valdone Maciulyte, Jasmin Zohren, Daniel M. Snell, Shantha K. Mahadevaiah, Obah A. Ojarikre, Peter J. I. Ellis & James M. A. Turner
Publicado en: Nature Communications, 2021, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-27227-2

A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation

Autores: Shantha K. Mahadevaiah, Mahesh N. Sangrithi, Takayuki Hirota, James M. A. Turner
Publicado en: Nature, Edición 586/7830, 2020, Página(s) 612-617, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-020-2629-6

Epigenetics drive the evolution of sex chromosomes in animals and plants

Autores: Aline Muyle, Doris Bachtrog, Gabriel A. B. Marais, James M. A. Turner
Publicado en: Philosophical Transactions of the Royal Society B: Biological Sciences, Edición 376/1826, 2021, Página(s) 20200124, ISSN 0962-8436
Editor: Royal Society of London
DOI: 10.1098/rstb.2020.0124

Frequent loss of heterozygosity in CRISPR-Cas9–edited early human embryos

Autores: Gregorio Alanis-Lobato, Jasmin Zohren, Afshan McCarthy, Norah M. E. Fogarty, Nada Kubikova, Emily Hardman, Maria Greco, Dagan Wells, James M. A. Turner, Kathy K. Niakan
Publicado en: Proceedings of the National Academy of Sciences, Edición 118/22, 2021, Página(s) e2004832117, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2004832117

Human Embryogenesis: A Comparative Perspective

Autores: Claudia Gerri, Sergio Menchero, Shantha K. Mahadevaiah, James M.A. Turner, Kathy K. Niakan
Publicado en: Annual Review of Cell and Developmental Biology, Edición 36/1, 2020, Página(s) 411-440, ISSN 1081-0706
Editor: Annual Reviews, Inc.
DOI: 10.1146/annurev-cellbio-022020-024900

DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line

Autores: Elias ElInati, Helen R. Russell, Obah A. Ojarikre, Mahesh Sangrithi, Takayuki Hirota, Dirk G. de Rooij, Peter J. McKinnon, James M. A. Turner
Publicado en: Proceedings of the National Academy of Sciences, Edición 114/47, 2017, Página(s) 12536-12541, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.1712530114

Fertile offspring from sterile sex chromosome trisomic mice

Autores: Takayuki Hirota, Hiroshi Ohta, Benjamin E. Powell, Shantha K. Mahadevaiah, Obah A. Ojarikre, Mitinori Saitou, James M. A. Turner
Publicado en: Science, Edición 357/6354, 2017, Página(s) 932-935, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.aam9046

Mammalian X Chromosome Dosage Compensation: Perspectives From the Germ Line

Autores: Mahesh N. Sangrithi, James M. A. Turner
Publicado en: BioEssays, Edición 40/6, 2018, Página(s) 1800024, ISSN 0265-9247
Editor: John Wiley & Sons Inc.
DOI: 10.1002/bies.201800024

SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice

Autores: Takayuki Hirota, Paul Blakeley, Mahesh N. Sangrithi, Shantha K. Mahadevaiah, Vesela Encheva, Ambrosius P. Snijders, Elias ElInati, Obah A. Ojarikre, Dirk G. de Rooij, Kathy K. Niakan, James M.A. Turner
Publicado en: Developmental Cell, Edición 47/5, 2018, Página(s) 645-659.e6, ISSN 1534-5807
Editor: Cell Press
DOI: 10.1016/j.devcel.2018.10.004

Meiotic Silencing in Mammals

Autores: James M.A. Turner
Publicado en: Annual Review of Genetics, Edición 49/1, 2015, Página(s) 395-412, ISSN 0066-4197
Editor: Annual Reviews, Inc.
DOI: 10.1146/annurev-genet-112414-055145

Non-Canonical and Sexually Dimorphic X Dosage Compensation States in the Mouse and Human Germline

Autores: Mahesh N. Sangrithi, Helene Royo, Shantha K. Mahadevaiah, Obah Ojarikre, Leena Bhaw, Abdul Sesay, Antoine H.F.M. Peters, Michael Stadler, James M.A. Turner
Publicado en: Developmental Cell, Edición 40/3, 2017, Página(s) 289-301.e3, ISSN 1534-5807
Editor: Cell Press
DOI: 10.1016/j.devcel.2016.12.023

The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes

Autores: Elias ElInati, Agata P. Zielinska, Afshan McCarthy, Nada Kubikova, Valdone Maciulyte, Shantha Mahadevaiah, Mahesh N. Sangrithi, Obah Ojarikre, Dagan Wells, Kathy K. Niakan, Melina Schuh, James M. A. Turner
Publicado en: Nature Communications, Edición 11/1, 2020, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-020-16441-z

ATR is a multifunctional regulator of male mouse meiosis

Autores: Alexander Widger, Shantha K. Mahadevaiah, Julian Lange, Elias ElInati, Jasmin Zohren, Takayuki Hirota, Sarai Pacheco, Andros Maldonado-Linares, Marcello Stanzione, Obah Ojarikre, Valdone Maciulyte, Dirk G. de Rooij, Attila Tóth, Ignasi Roig, Scott Keeney, James M.A. Turner
Publicado en: Nature Communications, Edición 9/1, 2018, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-018-04850-0

Author Correction: Scalable and robust SARS-CoV-2 testing in an academic center

Autores: Jim Aitken, Karen Ambrose, Sam Barrell, Rupert Beale, Ganka Bineva-Todd, Dhruva Biswas, Richard Byrne, Simon Caidan, Peter Cherepanov, Laura Churchward, Graham Clark, Margaret Crawford, Laura Cubitt, Vicky Dearing, Christopher Earl, Amelia Edwards, Chris Ekin, Efthymios Fidanis, Alessandra Gaiba, Steve Gamblin, Sonia Gandhi, Jacki Goldman, Robert Goldstone, Paul R. Grant, Maria Greco, Judith Heane
Publicado en: Nature Biotechnology, Edición 38/8, 2020, Página(s) 1000-1000, ISSN 1087-0156
Editor: Nature Publishing Group
DOI: 10.1038/s41587-020-0623-z

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