Risultati finali Websites, patent fillings, videos etc. (5) Individualized press release for every partner Final dissemination and exploitation report Initial Dissemination plan Launch of website, Twitter and LinkedIn account Final symposium/stakeholder meeting on project results Final symposiumstakeholder meeting on project results Pubblicazioni Peer reviewed articles (194) Relationship Between Blood Pressure and Incident Cardiovascular Disease Autori: Malik et.al. Pubblicato in: Hypertension, 2021, ISSN 0194-911X Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/hypertensionaha.120.16534 Effect sizes of BOLD CVR, resting-state signal fluctuations and time delay measures for the assessment of hemodynamic impairment in carotid occlusion patients Autori: Jill B. De Vis, Alex A. Bhogal, Jeroen Hendrikse, Esben T. Petersen, Jeroen C.W. Siero Pubblicato in: NeuroImage, Issue 179, 2018, Page(s) 530-539, ISSN 1053-8119 Editore: Academic Press DOI: 10.1016/j.neuroimage.2018.06.017 A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease. Autori: Stringer MS, Lee H, Huuskonen MT, MacIntosh BJ, Brown R, Montagne A, Atwi S, Ramirez J, Jansen MA, Marshall I, Black SE, Zlokovic BV, Benveniste H, Wardlaw JM Pubblicato in: Translational Stroke Research, 2020, ISSN 1868-4483 Editore: Springer Pub. Co., DOI: 10.1007/s12975-020-00843-8 Clinical management of cerebral small vessel disease: a call for a holistic approach. Autori: Clancy U, Appleton JP, Arteaga C, Doubal FN, Bath PM, Wardlaw JM Pubblicato in: Chinese medical journal, 2020, ISSN 0366-6999 Editore: Zhonghua Yixeuehui Zazhishe/Chinese Medical Association Publishing House DOI: 10.1097/cm9.0000000000001177 Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis Autori: Gill D, Georgakis MK, Zuber V, Karhunen V, Burgess S, Malik R, Dichgans M Pubblicato in: Journal of the American Heart Association, Issue 9(14), 2020, Page(s) e016773, ISSN 2047-9980 Editore: Wiley-Blackwell DOI: 10.1161/jaha.120.016773 Effects of cilostazol and isosorbide mononitrate on cerebral haemodynamics in the LACI-1 randomised controlled trial Autori: Blair GW, Janssen E, Stringer MS, Thrippleton MJ, Chappell F, Shi Y, Hamilton I, Flathery K, Appleton JP, Doubal FN, Bath PM, Wardlaw JM Pubblicato in: Stroke, 2021, ISSN 0039-2499 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/strokeaha.121.034866 Impaired Cerebral Autoregulation After Subarachnoid Hemorrhage: A Quantitative Assessment Using a Mouse Model. Autori: Koide M, Ferris HR, Nelson MT, Wellman GC. Pubblicato in: Front Physiol, 2021, ISSN 1664-042X Editore: Frontiers Research Foundation DOI: 10.3389/fphys.2021.688468 Post-stroke Cognition at 1 and 3 Years Is Influenced by the Location of White Matter Hyperintensities in Patients With Lacunar Stroke Autori: Maria del C. Valdés Hernández,1,* Tara Grimsley-Moore,2 Francesca M. Chappell,1 Michael J. Thrippleton,1 Paul A. Armitage,3 Eleni Sakka,1 Stephen Makin,4 and Joanna M. Wardlaw1 Pubblicato in: Front Neurol., 2021, ISSN 1662-453X Editore: Frontiers DOI: 10.3389/fneur.2021.634460 Circulating Metabolites Differentiate Acute Ischemic Stroke from Stroke Mimics Autori: Tiedt S, Brandmaier S, Kollmeier H, Duering M, Artati A, Adamski J, Klein M, Liebig T, Holdt LM, Teupser D, Wang-Sattler R, Schwedhelm E, Gieger C, Dichgans M Pubblicato in: Annals of Neurology, Issue 88(4), 2020, Page(s) 736-746, ISSN 1531-8249 Editore: Wiley DOI: 10.1002/ana.25859 Dose-response relationship between genetically proxied average blood glucose levels and incident coronary heart disease in individuals without diabetes mellitus Autori: Burgess S, Malik R, Liu B, Mason AM, Georgakis MK, Dichgans M, Gill D Pubblicato in: Diabetologia, Issue 64(4), 2021, Page(s) 845-849, ISSN 0012-186X Editore: Springer Verlag DOI: 10.1007/s00125-020-05377-0 Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension. Autori: Kerkhofs D, van Hagen BT, Milanova IV, Schell KJ, van Essen H, Wijnands E, Goossens P, Blankesteijn WM, Unger T, Prickaerts J, Biessen EA, van Oostenbrugge RJ, Foulquier S Pubblicato in: Theranostics, 2020, ISSN 0028-3878 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/wnl.0000000000011783 Correlations in post-mortem imaging-histopathology studies of sporadic human cerebral small vessel disease: a systematic review Autori: Catherine A Humphreys , Colin Smith , Joanna M Wardlaw Pubblicato in: Neuropathol Appl Neurobiol, 2021, ISSN 1365-2990 Editore: John Wiley & Sons, Inc. DOI: 10.1111/nan.12737 Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts Autori: Nick A Weaver, Hugo J Kuijf, Hugo P Aben, Jill Abrigo, Hee-Joon Bae, Mélanie Barbay, Jonathan G Best, Régis Bordet, Francesca M Chappell, J Matthijs Biesbroek, Geert Jan Biessels Pubblicato in: Lancet Neurol, 2021, ISSN 1474-4422 Editore: The Lancet Publishing Group DOI: 10.1016/s1474-4422(21)00060-0 Non-Invasive Assessment of Damping of Blood Flow Velocity Pulsatility in Cerebral Arteries With MRI Autori: Tine Arts, MS,1 Laurien P. Onkenhout, MS,1 Raquel P. Amier, MS,3 Rob van der Geest, PhD,4 Thijs van Harten, MS,4 Jaap Kappelle, MD,2 Sanne Kuipers, MS,2 Matthijs J.P. van Osch, PhD,4 Ed T. van Bavel, PhD,5 Geert Jan Biessels, MD,2 and Jaco J.M. Zwanenburg Pubblicato in: Journal of Magnetic Resonance Imaging, 2021, ISSN 1090-7807 Editore: Academic Press DOI: 10.1002/jmri.27989 Associations between total MRI-visible small vessel disease burden and domain-specific cognitive abilities in a community-dwelling older-age cohort Autori: Okl Hamilton , S R Cox , L Ballerini , M E Bastin , J Corley , A J Gow , S Muñoz Maniega , P Redmond , M Del C Valdés Hernández , J M Wardlaw , I J Deary Pubblicato in: Neurobiol Aging, 2021, ISSN 0197-4580 Editore: Elsevier BV DOI: 10.1016/j.neurobiolaging.2021.04.007 Additive Effects of Genetic Interleukin-6 Signaling Downregulation and Low-Density Lipoprotein Cholesterol Lowering on Cardiovascular Disease: A 2×2 Factorial Mendelian Randomization Analysis. Autori: Georgakis MK, Malik R, Burgess S, Dichgans M. Pubblicato in: J Am Heart Assoc, Issue 2022 Jan 4, 2022, Page(s) 11(1):e023277, ISSN 2047-9980 Editore: Wiley-Blackwell DOI: 10.1161/jaha.121.023277 Associations Between White Matter Hyperintensity Burden, Cerebral Blood Flow and Transit Time in Small Vessel Disease: An Updated Meta-Analysis Autori: Catriona R Stewart , Michael S Stringer, Yulu Shi , Michael J Thrippleton, Joanna M Wardlaw Pubblicato in: Front Neurol, 2021, ISSN 1662-453X Editore: Frontiers DOI: 10.3389/fneur.2021.647848 Circadian control of brain glymphatic and lymphatic fluid flow. Autori: Hablitz LM, Plá V, Giannetto M, Vinitsky HS, Stæger FF, Metcalfe T, Nguyen R, Benrais A, Nedergaard M Pubblicato in: Nature communications, 2020, ISSN 2041-1723 Editore: Nature Publishing Group DOI: 10.1038/s41467-020-18115-2 Genetically Predicted Blood Pressure Across the Lifespan: Differential Effects of Mean and Pulse Pressure on Stroke Risk Autori: Georgakis MK, Gill D, Malik R, Protogerou AD, Webb AJS, Dichgans M Pubblicato in: Hypertension, Issue 76(3), 2020, Page(s) 953-961, ISSN 1524-4563 Editore: American Heart Association DOI: 10.1161/hypertensionaha.120.15136 Sources of systematic error in DCE-MRI estimation of low-level blood-brain barrier leakage Autori: Cameron Manning,Michael Stringer,Ben Dickie,Una Clancy,Maria C. Valdés Hernandez,Stewart J. Wiseman,Daniela Jaime Garcia,Eleni Sakka,Walter H. Backes,Michael Ingrisch,Francesca Chappell,Fergus Doubal,Craig Buckley,Laura M. Parkes,Geoff J. M. Parker,Ian Marshall,Joanna M. Wardlaw,Michael J. Thrippleton Pubblicato in: Magnetic Resonance in Medicine, 2021, ISSN 1522-2594 Editore: Wiley DOI: 10.1002/mrm.28833 ATP- and voltage-dependent electro-metabolic signaling regulates blood flow in heart Autori: Guiling Zhao, Humberto C. Joca, Mark T. Nelson, W. Jonathan Lederer Pubblicato in: Proceedings of the National Academy of Sciences, Issue 117/13, 2020, Page(s) 7461-7470, ISSN 0027-8424 Editore: National Academy of Sciences DOI: 10.1073/pnas.1922095117 Zooming in on cerebral small vessel function in small vessel diseases with 7T MRI: Rationale and design of the “ZOOM@SVDs ”study Autori: Hilde van den Brink a , Anna Kopczak b , Tine Arts c , Laurien Onkenhout a , Jeroen C.W. Siero c , d , Jaco J.M. Zwanenburg c , Marco Duering b , e , f , Gordon W. Blair g , Fergus N.Doubal g , Michael S. Stringer g , Michael J. Thrippleton g , Hugo J. Kuijf h , Alberto de Luca a , g , Jeroen Hendrikse c , Joanna M. Wardlaw g , Martin Dichgans b , e , f , Geert Jan Biessels a , ∗ , on behalf of Pubblicato in: Cerebral Circulation - Cognition and Behavior, 2021, ISSN 2666-2450 Editore: Elseveir DOI: 10.1016/j.cccb.2021.100013 Evaluation of Enhanced Learning Techniques for Segmenting Ischaemic Stroke Lesions in Brain Magnetic Resonance Perfusion Images Using a Convolutional Neural Network Scheme Autori: Carlos Uziel Pérez Malla, Maria del C. Valdés Hernández, Muhammad Febrian Rachmadi, Taku Komura Pubblicato in: Frontiers in Neuroinformatics, Issue 13, 2019, ISSN 1662-5196 Editore: Frontiers Research Foundation DOI: 10.3389/fninf.2019.00033 Cardiac Risk Factors for Stroke: A Comprehensive Mendelian Randomization Study Autori: Frerich S, Malik R, Georgakis MK, Sinner MF, Kittner SJ, Mitchell BD, Dichgans M. Pubblicato in: Stroke, 2021, ISSN 0039-2499 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/strokeaha.121.036306 Zinc drives vasorelaxation by acting on sensory nerves, endothelium and smooth muscle Autori: Betrie AH, Brock JA, Harraz OF, Bush AI, He G-W, Nelson MT, Angus JA, Wright CE, Ayton S Pubblicato in: Nat Commun, 2021, ISSN 2041-1723 Editore: Nature Publishing Group DOI: 10.1038/s41467-021-23198-6 Early life predictors of late life cerebral small vessel disease in four prospective cohort studies. Autori: Backhouse EV, Shenkin SD, McIntosh AM, Bastin ME, Whalley HC, Valdez Hernandez M, Muñoz Maniega S, Harris MA, Stolicyn A, Campbell A, Steele D, Waiter GD, Sandu AL, Waymont JMJ, Murray AD, Cox SR, de Rooij SR, Roseboom TJ, Wardlaw JM. Pubblicato in: Brain, Issue 2021 Sep 28:awab331, 2021, ISSN 0006-8950 Editore: Oxford University Press DOI: 10.1093/brain/awab331 Cognitive impairment in sporadic cerebral small vessel disease: A systematic review and meta-analysis. Autori: Hamilton OKL, Backhouse EV, Janssen E, Jochems ACC, Maher C, Ritakari TE, Stevenson AJ, Xia L, Deary IJ, Wardlaw JM Pubblicato in: Alzheimer's & dementia : the journal of the Alzheimer's Association, 2020, ISSN 1552-5279 Editore: Alzheimer’s Association DOI: 10.1002/alz.12221 Blood-brain barrier leakage at baseline and cognitive decline in cerebral small vessel disease: a 2-year follow-up study. Autori: Kerkhofs D, Wong SM, Zhang E, Uiterwijk R, Hoff EI, Jansen JFA, Staals J, Backes WH, van Oostenbrugge RJ Pubblicato in: Geroscience, 2021, ISSN 2509-2715 Editore: Springer DOI: 10.1007/s11357-021-00399-x Cerebral small vessel disease burden and longitudinal cognitive decline from age 73 to 82: the Lothian Birth Cohort 1936. Autori: Hamilton OKL, Cox SR, Okely JA, Conte F, Ballerini L, Bastin ME, Corley J, Taylor AM, Page D, Gow AJ, Muñoz Maniega S, Redmond P, Valdés-Hernández MDC, Wardlaw JM, Deary IJ. Pubblicato in: Transl Psychiatry., 2021, ISSN 2158-3188 Editore: Nature Publishing Group DOI: 10.1038/s41398-021-01495-4 Sex differences in cerebral small vessel disease: a systematic review and meta-analysis. Autori: Jiménez-Sánchez L, Hamilton OJ, Clancy U, Backhouse E, Stewart CR, Stringer MS, Doubal FN, Wardlaw JM Pubblicato in: Front Neurol, 2021, ISSN 1662-453X Editore: Frontiers DOI: 10.3389/fneur.2021.756887 PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity Autori: Dabertrand F, Harraz OF, Koide M, Longden TA, Rosehart AC, Hill-Eubanks DC, Joutel A, Nelson MT Pubblicato in: PNAS, 2021, ISSN 1091-6490 Editore: PNAS DOI: 10.1073/pnas.2025998118 Improving Clinical Detection of Acute Lacunar Stroke Autori: Arba F, Mair G, Phillips S, Sandercock P, Wardlaw JM Pubblicato in: Stroke, 2021, ISSN 0039-2499 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/strokeaha.119.028402 Imaging NeuroVascular, Endothelial and STructural Integrity in prepAration to TrEat Small Vessel Diseases. The INVESTIGATE-SVDs study Protocol. Part of the SVDs@Target Project Autori: Blair GW, Stringer MS, Thrippleton MJ, Chappell FM, Shuler K, Hamilton I, Garcia DJ, Doubal FN, Kopczak A, Duering M, Ingrisch M, Kerkhofs D, Staals J, van den Brink H, Arts T, Backes W,. Pubblicato in: Cereb Circ Cogn Behav, 2021, ISSN 2666-2450 Editore: Elsevier DOI: 10.1016/j.cccb.2021.100020 The striatum, the hippocampus, and short-term memory binding: Volumetric analysis of the subcortical grey matter's role in mild cognitive impairment Autori: Maria C. Valdés Hernández, Rupert Clark, Szu-Han Wang, Federica Guazzo, Clara Calia, Vivek Pattan, John Starr, Sergio Della Sala, Mario Alfredo Parra Pubblicato in: NeuroImage: Clinical, Issue 25, 2020, Page(s) 102158, ISSN 2213-1582 Editore: Elsevier BV DOI: 10.1016/j.nicl.2019.102158 Mendelian randomization for studying the effects of perturbing drug targets Autori: Gill. D. et. al Pubblicato in: Wellcome Open Research, Issue 10;6:16, 2021, Page(s) 10;6:16, ISSN 2398-502X Editore: F1000Research DOI: 10.12688/wellcomeopenres.16544.2 Identification of plasma proteins relating to brain neurodegeneration and vascular pathology in cognitively normal individuals. Autori: Shi L, Buchanan CR, Cox SR, Hillary RF, Marioni RE, Campbell A, Hayward C, Stolicyn A, Whalley HC, Harris MA, Waymont J, Waiter G, Backhouse E, Wardlaw JM, Steele D, Mcintosh A, Lovestone S, Buckley NJ, Nevado-Holgado AJ. Pubblicato in: Alzheimers Dement, 2021, ISSN 1552-5279 Editore: Alzheimer’s Association DOI: 10.1002/dad2.12240 Cerebral Vascular Dysfunctions Detected in Human Small Vessel Disease and Implications for Preclinical Studies. Autori: Wardlaw JM, Benveniste H, Williams A. Pubblicato in: Annu Rev Physiol, 2021, ISSN 1545-1585 Editore: Annual Reviews DOI: 10.1146/annurev-physiol-060821-014521 Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice. Autori: Giannetto M, Xia M, Stæger FF, Metcalfe T, Vinitsky HS, Dang JAML, Xavier ALR, Kress BT, Nedergaard M, Hablitz LM Pubblicato in: Nature, 2020, ISSN 2041-1723 Editore: Nature Publishing Group DOI: 10.1038/s41598-020-72621-3 A Comparison of CVR Magnitude and Delay Assessed at 1.5 and 3T in Patients With Cerebral Small Vessel Disease. Autori: Stringer MS, Blair GW, Shi Y, Hamilton I, Dickie DA, Doubal FN, Marshall IM, Thrippleton MJ, Wardlaw JM. Pubblicato in: Front Physiol., 2021, ISSN 1664-042X Editore: Frontiers Research Foundation DOI: 10.3389/fphys.2021.644837 Contractile pericytes determine the direction of blood flow at capillary junctions Autori: Gonzales AL, Klug NR, Moshkforoush A, Lee JC, Lee FK, Shui B, Tsoukias NM, Kotlikoff MI, Hill-Eubanks D, Nelson MT Pubblicato in: PNAS, 2021, ISSN 1091-6490 Editore: PNAS DOI: 10.1073/pnas.1922755117 Diagnosing vascular cognitive impairment: Current challenges and future perspectives Autori: J Matthijs Biesbroek, Geert Jan Biessels Pubblicato in: International Journal of Stroke, 2021, ISSN 0271-678X Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1177/17474930211073387 Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank Autori: Malik, Rainer; Georgakis, Marios K.; Neitzel, Julia; Rannikmäe, Kristiina; Ewers, Michael; Seshadri, Sudha; Sudlow, Cathie L.M.; Dichgans, Martin Pubblicato in: Alzheimers Dement, Issue 17(9), 2021, Page(s) 1422-1431, ISSN 1552-5279 Editore: Alzheimer's Association DOI: 10.1002/alz.12320 Arterial CO2 pressure changes during hypercapnia are associated with changes in brain parenchymal volume Autori: Lisa A. van der Kleij, Jill B. De Vis, Jeroen de Bresser, Jeroen Hendrikse, Jeroen C. W. Siero Pubblicato in: European Radiology Experimental, Issue 4/1, 2020, ISSN 2509-9280 Editore: Springer Nature DOI: 10.1186/s41747-020-0144-z Cerebral Amyloid Angiopathy: Still a Syndromal Diagnosis. Autori: Biessels GJ Pubblicato in: Stroke, 2020, ISSN 0039-2499 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/strokeaha.120.032703 Strain Tensor Imaging: Cardiac-induced brain tissue deformation in humans quantified with high-field MRI Autori: Jacob-JanSloots,Geert JanBiessels,Albertode Luca, Jaco J.M.Zwanenburg Pubblicato in: NeuroImage, 2021, ISSN 1053-8119 Editore: Academic Press DOI: 10.1016/j.neuroimage.2021.118078 Brain network reorganisation and spatiallesion distribution in systemic lupuserythematosus Autori: Valdés Hernández MDC, Smith K, Bastin ME, Nicole Amft E, Ralston SH, Wardlaw JM, Wiseman SJ Pubblicato in: Lupus, 2021, ISSN 2158-2440 Editore: SAGE Publications Inc. DOI: 10.1177/0961203320979045 Cognitive ability, education and socioeconomic status in childhood and risk of post-stroke depression in later life: A systematic review and meta-analysis Autori: Ellen V. Backhouse, Caroline A. McHutchison, Vera Cvoro, Susan D. Shenkin, Joanna M. Wardlaw Pubblicato in: PLOS ONE, Issue 13/7, 2018, Page(s) e0200525, ISSN 1932-6203 Editore: Public Library of Science DOI: 10.1371/journal.pone.0200525 Prognostic Significance of Blood Pressure Variability on Beat-to-Beat Monitoring After Transient Ischemic Attack and Stroke Autori: Alastair J.S. Webb, Sara Mazzucco, Linxin Li, Peter M. Rothwell Pubblicato in: Stroke, Issue 49/1, 2018, Page(s) 62-67, ISSN 0039-2499 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/STROKEAHA.117.019107 Time course of blood pressure control prior to lacunar TIA and stroke Autori: Linxin Li, Sarah J.V. Welch, Sergei A. Gutnikov, Ziyah Mehta, Peter M. Rothwell Pubblicato in: Neurology, Issue 90/20, 2018, Page(s) e1732-e1741, ISSN 0028-3878 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/WNL.0000000000005526 Antiplatelet Treatment After Transient Ischemic Attack and Ischemic Stroke in Patients With Cerebral Microbleeds in 2 Large Cohorts and an Updated Systematic Review Autori: Kui Kai Lau, Caroline E. Lovelock, Linxin Li, Michela Simoni, Sergei Gutnikov, Wilhelm Küker, Henry Ka Fung Mak, Peter M. Rothwell Pubblicato in: Stroke, Issue 49/6, 2018, Page(s) 1434-1442, ISSN 0039-2499 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/STROKEAHA.117.020104 Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging Autori: Caroline M.J. Loos, Stephen D.J. Makin, Julie Staals, Martin S. Dennis, Robert J. van Oostenbrugge, Joanna M. Wardlaw Pubblicato in: Stroke, Issue 49/5, 2018, Page(s) 1183-1188, ISSN 0039-2499 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/STROKEAHA.117.020495 Vascular reactivity in small cerebral perforating arteries with 7 T phase contrast MRI – A proof of concept study Autori: Lennart J. Geurts, Alex A. Bhogal, Jeroen C.W. Siero, Peter R. Luijten, Geert Jan Biessels, Jaco J.M. Zwanenburg Pubblicato in: NeuroImage, Issue 172, 2018, Page(s) 470-477, ISSN 1053-8119 Editore: Academic Press DOI: 10.1016/j.neuroimage.2018.01.055 The effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic stroke Autori: Stephen DJ Makin, Fergus N Doubal, Terence J Quinn, Philip MW Bath, Martin S Dennis, Joanna M Wardlaw Pubblicato in: European Stroke Journal, Issue 3/1, 2017, Page(s) 66-73, ISSN 2396-9873 Editore: SAGE Journals DOI: 10.1177/2396987317728854 Age-Specific Associations of Renal Impairment With Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease in Transient Ischemic Attack and Stroke Autori: Bian Liu, Kui Kai Lau, Linxin Li, Caroline Lovelock, Ming Liu, Wilhelm Kuker, Peter M. Rothwell Pubblicato in: Stroke, Issue 49/4, 2018, Page(s) 899-904, ISSN 0039-2499 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/STROKEAHA.117.019650 Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke Autori: Caroline A McHutchison, Vera Cvoro, Stephen Makin, Francesca M Chappell, Kirsten Shuler, Joanna M Wardlaw Pubblicato in: Journal of Neurology, Neurosurgery & Psychiatry, Issue 436-443, 2018, Page(s) jnnp-2018-319134, ISSN 0022-3050 Editore: BMJ Publishing Group DOI: 10.1136/jnnp-2018-319134 Small vessel disease is associated with altered cerebrovascular pulsatility but not resting cerebral blood flow Autori: Yulu Shi, Michael J Thrippleton, Gordon W Blair, David A Dickie, Ian Marshall, Iona Hamilton, Fergus N Doubal, Francesca Chappell, Joanna M Wardlaw Pubblicato in: Journal of Cerebral Blood Flow & Metabolism, 2018, Page(s) 0271678X1880395, ISSN 0271-678X Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1177/0271678x18803956 Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting Autori: Ganesh Chauhan, Hieab H.H. Adams, Claudia L. Satizabal, Joshua C. Bis, Alexander Teumer, Muralidharan Sargurupremraj, Edith Hofer, Stella Trompet, Saima Hilal, Albert Vernon Smith, Xueqiu Jian, Rainer Malik, Matthew Traylor, Sara L. Pulit, Philippe Amouyel, Bernard Mazoyer, Yi-Cheng Zhu, Sara Kaffashian, Sabrina Schilling, Gary W. Beecham, Thomas J. Montine, Gerard D. Schellenberg, Olafur Kjartans Pubblicato in: Neurology, Issue 92/5, 2019, Page(s) e486-e503, ISSN 0028-3878 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1212/wnl.0000000000006851 MRI measurement of blood-brain barrier leakage: minding the gaps Autori: Michael Jonathan Thrippleton Pubblicato in: The Journal of Physiology, Issue 597/3, 2019, Page(s) 667-668, ISSN 0022-3751 Editore: Blackwell Publishing Inc. DOI: 10.1113/jp277425 Intracranial pulsatility in patients with cerebral small vessel disease: a systematic review Autori: Yulu Shi, Michael J. Thrippleton, Ian Marshall, Joanna M. Wardlaw Pubblicato in: Clinical Science, Issue 132/1, 2018, Page(s) 157-171, ISSN 0143-5221 Editore: Portland Press, Ltd. DOI: 10.1042/cs20171280 Cerebrovascular reactivity measurement in cerebral small vessel disease: Rationale and reproducibility of a protocol for MRI acquisition and image processing Autori: Michael J Thrippleton, Yulu Shi, Gordon Blair, Iona Hamilton, Gordon Waiter, Christian Schwarzbauer, Cyril Pernet, Peter JD Andrews, Ian Marshall, Fergus Doubal, Joanna M Wardlaw Pubblicato in: International Journal of Stroke, Issue 13/2, 2017, Page(s) 195-206, ISSN 1747-4930 Editore: Blackwell DOI: 10.1177/1747493017730740 A protocol for precise comparisons of small vessel disease lesions between ex vivo magnetic resonance imaging and histopathology Autori: Catherine A Humphreys, Maurits A Jansen, Susana Muñoz Maniega, Víctor González-Castro, Cyril Pernet, Ian J Deary, Rustam Al-Shahi Salman, Joanna M Wardlaw, Colin Smith Pubblicato in: International Journal of Stroke, 2018, Page(s) 174749301879996, ISSN 1747-4930 Editore: Blackwell DOI: 10.1177/1747493018799962 Age and sex-specific associations of carotid pulsatility with small vessel disease burden in transient ischemic attack and ischemic stroke Autori: Kui Kai Lau, Petra Pego, Sara Mazzucco, Linxin Li, Dominic PJ Howard, Wilhelm Küker, Peter M Rothwell Pubblicato in: International Journal of Stroke, Issue 13/8, 2018, Page(s) 832-839, ISSN 1747-4930 Editore: Blackwell DOI: 10.1177/1747493018784448 Long-Term Premorbid Blood Pressure and Cerebral Small Vessel Disease Burden on Imaging in Transient Ischemic Attack and Ischemic Stroke Autori: Kui Kai Lau, Linxin Li, Michela Simoni, Ziyah Mehta, Wilhelm Küker, Peter M. Rothwell Pubblicato in: Stroke, Issue 49/9, 2018, Page(s) 2053-2060, ISSN 0039-2499 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/strokeaha.118.021578 MRI Relaxometry for Quantitative Analysis of USPIO Uptake in Cerebral Small Vessel Disease Autori: Michael Thrippleton, Gordon Blair, Maria Valdes-Hernandez, Andreas Glatz, Scott Semple, Fergus Doubal, Alex Vesey, Ian Marshall, David Newby, Joanna Wardlaw Pubblicato in: International Journal of Molecular Sciences, Issue 20/3, 2019, Page(s) 776, ISSN 1422-0067 Editore: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms20030776 Higher Pulsatility in Cerebral Perforating Arteries in Patients With Small Vessel Disease Related Stroke, a 7T MRI Study Autori: Lennart J. Geurts, Jaco J.M. Zwanenburg, Catharina J.M. Klijn, Peter R. Luijten, Geert Jan Biessels Pubblicato in: Stroke, Issue 50/1, 2019, Page(s) 62-68, ISSN 0039-2499 Editore: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/strokeaha.118.022516 The Glymphatic System in Central Nervous System Health and Disease: Past, Present, and Future Autori: Benjamin A. Plog, Maiken Nedergaard Pubblicato in: Annual Review of Pathology: Mechanisms of Disease, Issue 13/1, 2018, Page(s) 379-394, ISSN 1553-4006 Editore: Annual Reviews, Inc. DOI: 10.1146/annurev-pathol-051217-111018 Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: A systematic review and meta-analysis Autori: Farah Francis, Lucia Ballerini, Joanna M Wardlaw Pubblicato in: International Journal of Stroke, 2019, Page(s) 174749301983032, ISSN 1747-4930 Editore: Blackwell DOI: 10.1177/1747493019830321 Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease Autori: Emma L. Bailey, Martin W. McBride, John D. McClure, Wendy Beattie, Delyth Graham, Anna F. Dominiczak, Colin Smith, Joanna M. 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