Deliverables
Contrast agent particles leads optimization and upscale development
Preliminary exploitation strategy
Preliminary exploitation strategy based on midterm results
Identification of the sensitivity threshold for the preparation of SPCCT contrast agentsFinal exploitation strategy report
Selection of the most promising nanoparticles to be used as contrast agents for SPCCT
Report of results on small animals
Report of results of SPCCT and selected contrast agents for Atherosclerotic Plaque Characterization and Thrombus, Stroke and Myocardial Infarction morphological and functional evaluation in small animals
Report of results on large animalsReport of results of SPCCT and selected contrast agents for Atherosclerotic Plaque Characterization and Thrombus Stroke and Myocardial Infarction morphological and functional evaluation in large animals
Functionalization of the nanoparticles for targeting relevant biomarkersFunctionalization of the nanoparticles for targeting relevant biomarkers in the diseases of interest in the project. Main cellular and in vivo tests
Ethics report on pre-clinical studiesEthics report and documents (including due authorisations) on pre-clinical studies
Communication plan and dissemination strategyCommunication plan and dissemination strategy towards all the identified stakeholder
management report 1management report, detailing and monitoring all management/internal coordination activities of the first period
Biodistribution of the contrast agent with active targeting to tropoelastinUpscale synthesis and biodistribution profile of a selected tropoelastin-targeted contrast agent, and assessment of its potential for further clinical/industrial translation
Report of preliminary results in humanReport of preliminary results on SPCCT capabilities in human for carotid arteries (lumen and plaque) and stroke analysis
Comprehensive overview of current care of imaging atherosclerotic patients in four major European countriesMid-term open Workshop on results of project phase 1, announcing project phase 2
Press release 1Press release 1, announcing the start of the project
Final press releasePress release 2
Press release 2 – results at mid-term
Publications
Author(s):
Elisa Cuccione, Peter Chhour, Salim Si-Mohamed, Chloé Dumot, Johoon Kim, Violaine Hubert, Claire Crola Da Silva, Marc Vandamme, Emmanuel Chereul, Joëlle Balegamire, Yves Chevalier, Yves Berthezène, Loïc Boussel, Philippe Douek, David P. Cormode, Marlène Wiart
Published in:
Nanotheranostics, Issue 4/3, 2020, Page(s) 129-141, ISSN 2206-7418
Publisher:
Nanotheranostics
DOI:
10.7150/ntno.45354
Author(s):
Alkystis Phinikaridou, Sara Lacerda, Begoña Lavin, Marcelo E. Andia, Alberto Smith, Prakash Saha, René M. Botnar
Published in:
Circulation: Cardiovascular Imaging, Issue 11/8, 2018, ISSN 1941-9651
Publisher:
Lippincott Williams & Wilkins Ltd.
DOI:
10.1161/circimaging.117.007303
Author(s):
Anne‐Claire Peultier, Dimitrios Venetsanos, Imran Rashid, Johan L. Severens, William K. Redekop
Published in:
Journal of Evaluation in Clinical Practice, Issue 26/5, 2020, Page(s) 1457-1466, ISSN 1356-1294
Publisher:
Blackwell Publishing Inc.
DOI:
10.1111/jep.13333
Author(s):
Arnaud Thivolet, Salim Si-Mohamed, Pierre-Emmanuel Bonnot, Christophe Blanchet, Vahan Képénékian, Loïc Boussel, Philippe Douek, Pascal Rousset
Published in:
Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-020-70282-w
Author(s):
Joëlle Balegamire, Marc Vandamme, Emmanuel Chereul, Salim Si-Mohamed, Samira Azzouz Maache, Eyad Almouazen, Laurent Ettouati, Hatem Fessi, Loïc Boussel, Philippe Douek, Yves Chevalier
Published in:
Biomaterials Science, Issue 8/20, 2020, Page(s) 5715-5728, ISSN 2047-4830
Publisher:
Royal Society of Chemistry
DOI:
10.1039/d0bm01046d
Author(s):
Salim Si-Mohamed, Sara Boccalini, Pierre-Antoine Rodesch, Riham Dessouky, Elias Lahoud, Thomas Broussaud, Monica Sigovan, Delphine Gamondes, Philippe Coulon, Yoad Yagil, Loïc Boussel, Philippe Douek
Published in:
Diagnostic and Interventional Imaging, Issue 102/5, 2021, Page(s) 305-312, ISSN 2211-5684
Publisher:
Elsevier Masson
DOI:
10.1016/j.diii.2021.01.001
Author(s):
Juan F. P. J. Abascal, Nicolas Ducros, Valeriya Pronina, Simon Rit, Pierre-Antoine Rodesch, Thomas Broussaud, Suzanne Bussod, Philippe C. Douek, Andreas Hauptmann, Simon Arridge, Francoise Peyrin
Published in:
IEEE Access, Issue 9, 2021, Page(s) 25632-25647, ISSN 2169-3536
Publisher:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1109/access.2021.3056150
Author(s):
Anne-Claire Peultier, Ken Redekop, Emmanuel Coche, Johan L Severens
Published in:
Expert Review of Pharmacoeconomics & Outcomes Research, Issue 18/2, 2017, Page(s) 177-189, ISSN 1473-7167
Publisher:
Future Drugs Ltd.
DOI:
10.1080/14737167.2018.1429270
Author(s):
Julia Dangelmaier, Daniel Bar-Ness, Heiner Daerr, Daniela Muenzel, Salim Si-Mohamed, Sebastian Ehn, Alexander A. Fingerle, Melanie A. Kimm, Felix K. Kopp, Loic Boussel, Ewald Roessl, Franz Pfeiffer, Ernst J. Rummeny, Roland Proksa, Philippe Douek, Peter B. Noël
Published in:
European Radiology, Issue 28/8, 2018, Page(s) 3318-3325, ISSN 0938-7994
Publisher:
Springer Verlag
DOI:
10.1007/s00330-017-5252-7
Author(s):
Martina Tripepi, Federico Capuana, Eliana Gianolio, Flávio Vinicius Crizóstomo Kock, Amerigo Pagoto, Rachele Stefania, Giuseppe Digilio, Silvio Aime
Published in:
Bioconjugate Chemistry, Issue 29/4, 2018, Page(s) 1428-1437, ISSN 1043-1802
Publisher:
American Chemical Society
DOI:
10.1021/acs.bioconjchem.8b00120
Author(s):
J F P J Abascal, N Ducros, F Peyrin
Published in:
Inverse Problems, Issue 34/12, 2018, Page(s) 124003, ISSN 0266-5611
Publisher:
Institute of Physics Publishing
DOI:
10.1088/1361-6420/aae1e7
Author(s):
Johoon Kim, Daniel Bar-Ness, Salim Si-Mohamed, Philippe Coulon, Ira Blevis, Philippe Douek, David P. Cormode
Published in:
Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-018-30570-y
Author(s):
Niki Halttunen, Frederic Lerouge, Frederic Chaput, Marc Vandamme, Szilvia Karpati, Salim Si-Mohamed, Monica Sigovan, Loic Boussel, Emmanuel Chereul, Philippe Douek, Stephane Parola
Published in:
Scientific Reports, Issue 9/1, 2019, Page(s) Sci Rep 9, 12090 (2019), ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-019-48641-z
Author(s):
Felix K. Kopp, Heiner Daerr, Salim Si-Mohamed, Andreas P. Sauter, Sebastian Ehn, Alexander A. Fingerle, Bernhard Brendel, Franz Pfeiffer, Ewald Roessl, Ernst J. Rummeny, Daniela Pfeiffer, Roland Proksa, Philippe Douek, Peter B. Noël
Published in:
Scientific Reports, Issue 8/1, 2018, Page(s) 2018; 8: 17386., ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-018-35888-1
Author(s):
Daniela Muenzel, Heiner Daerr, Roland Proksa, Alexander A. Fingerle, Felix K. Kopp, Philippe Douek, Julia Herzen, Franz Pfeiffer, Ernst J. Rummeny, Peter B. Noël
Published in:
European Radiology Experimental, Issue 1/1, 2017, Page(s) 2017;1(1):25., ISSN 2509-9280
Publisher:
European Radiology Experimental
DOI:
10.1186/s41747-017-0030-5
Author(s):
Salim Si-Mohamed, Arnaud Thivolet, Pierre-Emmanuel Bonnot, Daniel Bar-Ness, Vahan Képénékian, David P. Cormode, Philippe Douek, Pascal Rousset
Published in:
Investigative Radiology, Issue 53/10, 2018, Page(s) 629-639, ISSN 0020-9996
Publisher:
Lippincott Williams & Wilkins Ltd.
DOI:
10.1097/rli.0000000000000483
Author(s):
Isabelle Riederer, Salim Si-Mohamed, Sebastian Ehn, Daniel Bar-Ness, Peter B. Noël, Alexander A. Fingerle, Franz Pfeiffer, Ernst J. Rummeny, Philippe Douek, Daniela Pfeiffer
Published in:
PLOS ONE, Issue 14/2, 2019, Page(s) e0212679, ISSN 1932-6203
Publisher:
Public Library of Science
DOI:
10.1371/journal.pone.0212679
Author(s):
Isabelle Riederer, Daniel Bar-Ness, Melanie A. Kimm, Salim Si-Mohamed, Peter B. Noël, Ernst J. Rummeny, Philippe Douek, Daniela Pfeiffer
Published in:
Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-019-41737-6
Author(s):
S.A. Si-Mohamed, P.C. Douek, L. Boussel
Published in:
Journal d'imagerie diagnostique et interventionnelle, Issue 2/1, 2019, Page(s) 32-45, ISSN 2543-3431
Publisher:
ELSEVIER
DOI:
10.1016/j.jidi.2018.11.004
Author(s):
Yuxi C. Dong, Maryam Hajfathalian, Portia S. N. Maidment, Jessica C. Hsu, Pratap C. Naha, Salim Si-Mohamed, Marine Breuilly, Johoon Kim, Peter Chhour, Philippe Douek, Harold I. Litt, David P. Cormode
Published in:
Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-019-50332-8
Author(s):
Grischa Bratke, Tilman Hickethier, Daniel Bar-Ness, Alexander Christian Bunck, David Maintz, Gregor Pahn, Philippe Coulon, Salim Si-Mohamed, Philippe Douek, Monica Sigovan
Published in:
Investigative Radiology, Issue 55/2, 2020, Page(s) 61-67, ISSN 0020-9996
Publisher:
Lippincott Williams & Wilkins Ltd.
DOI:
10.1097/rli.0000000000000610
Author(s):
Salim Si-Mohamed, Valérie Tatard-Leitman, Alexis Laugerette, Monica Sigovan, Daniela Pfeiffer, Ernst J. Rummeny, Philippe Coulon, Yoad Yagil, Philippe Douek, Loic Boussel, Peter B. Noël
Published in:
Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-019-44821-z
Author(s):
Daniela Muenzel, Daniel Bar-Ness, Ewald Roessl, Ira Blevis, Matthias Bartels, Alexander A. Fingerle, Stefan Ruschke, Philippe Coulon, Heiner Daerr, Felix K. Kopp, Bernhard Brendel, Axel Thran, Michal Rokni, Julia Herzen, Loic Boussel, Franz Pfeiffer, Roland Proksa, Ernst J. Rummeny, Philippe Douek, Peter B. Noël
Published in:
Radiology, Issue 283/3, 2017, Page(s) 723-728, ISSN 0033-8419
Publisher:
Radiological Society of North America
DOI:
10.1148/radiol.2016160890
Author(s):
Roger Steadman, Christoph Herrmann, Amir Livne
Published in:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Issue 862, 2017, Page(s) 18-24, ISSN 0168-9002
Publisher:
Elsevier BV
DOI:
10.1016/j.nima.2017.05.010
Author(s):
Salim Si-Mohamed, David P. Cormode, Daniel Bar-Ness, Monica Sigovan, Pratap C. Naha, Jean-Baptiste Langlois, Lara Chalabreysse, Philippe Coulon, Ira Blevis, Ewald Roessl, Klaus Erhard, Loic Boussel, Philippe Douek
Published in:
Nanoscale, 2017, ISSN 2040-3364
Publisher:
Royal Society of Chemistry
DOI:
10.1039/C7NR01153A
Author(s):
David P. Cormode, Salim Si-Mohamed, Daniel Bar-Ness, Monica Sigovan, Pratap C. Naha, Joelle Balegamire, Franck Lavenne, Philippe Coulon, Ewald Roessl, Matthias Bartels, Michal Rokni, Ira Blevis, Loic Boussel, Philippe Douek
Published in:
Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-017-04659-9
Author(s):
Salim Si-Mohamed, Daniel Bar-Ness, Monica Sigovan, David P. Cormode, Philippe Coulon, Emmanuel Coche, Alain Vlassenbroek, Gabrielle Normand, Loic Boussel, Philippe Douek
Published in:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2017, ISSN 0168-9002
Publisher:
Elsevier BV
DOI:
10.1016/j.nima.2017.04.014
Author(s):
C. Chappard, J. Abascal, S. Bussod, S. Uk, S. Si-Mohamed, P. Douek, F. Peyrin
Published in:
Osteoarthritis and Cartilage, Issue 28, 2020, Page(s) S277-S278, ISSN 1063-4584
Publisher:
W. B. Saunders Co., Ltd.
DOI:
10.1016/j.joca.2020.02.442
Author(s):
Begoña Lavin, Sara Lacerda, Marcelo E Andia, Silvia Lorrio, Robert Bakewell, Alberto Smith, Imran Rashid, René M Botnar, Alkystis Phinikaridou
Published in:
Cardiovascular Research, 2019, ISSN 0008-6363
Publisher:
Elsevier BV
DOI:
10.1093/cvr/cvz178
Author(s):
Salim A. Si-Mohamed, Monica Sigovan, Jessica C. Hsu, Valérie Tatard-Leitman, Lara Chalabreysse, Pratap C. Naha, Thibaut Garrivier, Riham Dessouky, Miruna Carnaru, Loic Boussel, David P. Cormode, Philippe C. Douek
Published in:
Radiology, Issue 300/1, 2021, Page(s) 98-107, ISSN 0033-8419
Publisher:
Radiological Society of North America
DOI:
10.1148/radiol.2021203968
Author(s):
Anne-Claire Peultier, William K. Redekop, Diederik W.J. Dippel, Daniel Bereczki, Salim Si-Mohamed, Philippe C. Douek, Johan L. Severens
Published in:
Health Policy and Technology, Issue 8/3, 2019, Page(s) 261-267, ISSN 2211-8837
Publisher:
Elsevier BV
DOI:
10.1016/j.hlpt.2019.08.005
Author(s):
Cyril Mory, Bruno Sixou, Salim Si-Mohamed, Loïc Boussel, Simon Rit
Published in:
Physics in Medicine & Biology, Issue 63/23, 2018, Page(s) 235001, ISSN 1361-6560
Publisher:
iopSience
DOI:
10.1088/1361-6560/aaeaf2
Author(s):
Cyril Mory, Bernhard Brendel, Klaus Erhard, Simon Rit
Published in:
Fifth international conference on image formation in X-ray computed tomography, 2018
Publisher:
Fifth international conference on image formation in X-ray computed tomography
Author(s):
Klaus Erhard, Artur Sossin, Axel Thran, Michal Rokni, Bernhard Brendel, Heiner Daerr
Published in:
Medical Imaging 2018: Physics of Medical Imaging, 2018, Page(s) 46, ISBN 9781-510616363
Publisher:
SPIE
DOI:
10.1117/12.2293476
Author(s):
J. F. P. J. Abascal, S. Si-Mohamed, P. Douek, C. Chappard, F. Peyrin
Published in:
2019 27th European Signal Processing Conference (EUSIPCO), 2019, Page(s) 1-5, ISBN 978-9-0827-9703-9
Publisher:
IEEE
DOI:
10.23919/eusipco.2019.8902564
Author(s):
S. Bussod, J.F.P.J. Abascal, N. Ducros, C. Olivier, S. Si-Mohamed, P. Douek, C. Chappard, F. Peyrin
Published in:
2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019), 2019, Page(s) 1170-1173, ISBN 978-1-5386-3641-1
Publisher:
IEEE
DOI:
10.1109/isbi.2019.8759192
Author(s):
J Dangelmaier, D Bar-Ness, D Münzel, H Daerr, F Pfeiffer, R Proksa, E Rummeny, P Douek, P Noël
Published in:
RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, Issue 189/S 01, 2017, Page(s) S1-S124
Publisher:
RoFo
DOI:
10.1055/s-0037-1600231
Author(s):
Pierre-Antoine Rodesch, Si-Mohamed Salim, Simon Rit
Published in:
Sixth international conference on image formation in X-ray computed tomography, 2020
Publisher:
Sixth international conference on image formation in X-ray computed tomography
Author(s):
Clément Tavakoli, Elisa Cuccione, Chloe Dumot, David P. Cormode, Marlène Wiart, Hélène Elleaume, Emmanuel Brun
Published in:
Medical Imaging 2021: Physics of Medical Imaging, Issue Proceedings Volume 11595, 2021, Page(s) 164, ISBN 9781510640207
Publisher:
SPIE
DOI:
10.1117/12.2580841
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