Objetivo With this proposal I plan to dissect, at the genetic level, those circuits controlling goal-oriented movements in mice. In particular, we will focus on the very feature that makes goal-oriented movements so unique in the world of motor control, the spatial awareness of such movements, the fact that their execution is likely to obey a precise metric. I want to understand: (1) which neuronal circuits promote the initiation of targeted-movement and assess the genetic heterogeneity of these circuits. (2) Characterise the function of genetically identified circuit elements during movement execution, with the aim of understanding how the metric of motion is encoded. (3) Investigate how sensory maps and motor maps are aligned during development and probe their plasticity. In prospective (4), we aim to understand how changes in such circuits impinge on the development and evolution of innate behaviours such as predation. The French mathematician Henry Poincaré wrote that ‘The real space is motor space’. Embedded in this idea is the intimate relation between the perceptual encoding of space and motor execution. Accordingly, our research starts at the motor level and aims to move to the perceptual level. Ámbito científico natural sciencesbiological scienceszoologymammalogyprimatologynatural sciencesbiological sciencesgeneticsengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsnatural sciencesbiological sciencesbiological behavioural sciencesethologybiological interactionsnatural sciencescomputer and information sciencesartificial intelligencecomputational intelligence Programa(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Tema(s) ERC-StG-2015 - ERC Starting Grant Convocatoria de propuestas ERC-2015-STG Consulte otros proyectos de esta convocatoria Régimen de financiación ERC-STG - Starting Grant Institución de acogida UNITED KINGDOM RESEARCH AND INNOVATION Aportación neta de la UEn € 1 495 731,00 Dirección POLARIS HOUSE NORTH STAR AVENUE SN2 1FL Swindon Reino Unido Ver en el mapa Región South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Swindon Tipo de actividad Research Organisations Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 1 495 731,00 Beneficiarios (1) Ordenar alfabéticamente Ordenar por aportación neta de la UE Ampliar todo Contraer todo UNITED KINGDOM RESEARCH AND INNOVATION Reino Unido Aportación neta de la UEn € 1 495 731,00 Dirección POLARIS HOUSE NORTH STAR AVENUE SN2 1FL Swindon Ver en el mapa Región South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Swindon Tipo de actividad Research Organisations Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Participación en los programas de I+D de la UE Opens in new window Red de colaboración de HORIZON Opens in new window Coste total € 1 495 731,00