Nanobody-targeted photodynamic therapy to kill cancer

Informations projet

KILLCANCER

N° de convention de subvention: 677582

DOI 10.3030/677582

Projet clôturé

Date de signature de la CE 27 Avril 2016

Date de début 1 Juillet 2016

Date de fin 31 Decembre 2021

Financé au titre de

• EXCELLENT SCIENCE - European Research Council (ERC)

Coût total € 1 500 000,00

Contribution de l’UE € 1 500 000,00

Coordonné par

UNIVERSITEIT UTRECHT
Netherlands

Publications

Peer reviewed articles (12)

Dual Targeting of Endothelial and Cancer Cells Potentiates In Vitro Nanobody-Targeted Photodynamic Therapy

Auteurs: Vida Mashayekhi, Katerina T. Xenaki, Paul M.P. van Bergen en Henegouwen, Sabrina Oliveira
Publié dans: Cancers, Numéro 12/10, 2020, Page(s) 2732, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12102732

Nanobody-targeted photodynamic therapy for the treatment of feline oral carcinoma: a step towards translation to the veterinary clinic

Auteurs: Irati Beltrán Hernández, Guillaume C.M. Grinwis, Alessia Di Maggio, Paul M.P. van Bergen en Henegouwen, Wim E. Hennink, Erik Teske, Jan W. Hesselink, Sebastiaan A. van Nimwegen, Jan A. Mol and Sabrina Oliveira
Publié dans: Nanophotonics, 2021, ISSN 2192-8614
Éditeur: De Gruyter
DOI: 10.1515/nanoph-2021-0195

Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions

Auteurs: Demian van Straten, Vida Mashayekhi, Henriette de Bruijn, Sabrina Oliveira, Dominic Robinson
Publié dans: Cancers, Numéro 9/12, 2017, Page(s) 19, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers9020019

Nanobody-Targeted Photodynamic Therapy Selectively Kills Viral GPCR-Expressing Glioblastoma Cells

Auteurs: Timo W. M. De Groof, Vida Mashayekhi, Tian Shu Fan, Nick D. Bergkamp, Javier Sastre Toraño, Jeffrey R. van Senten, Raimond Heukers, Martine J. Smit, Sabrina Oliveira
Publié dans: Molecular Pharmaceutics, Numéro 16/7, 2019, Page(s) 3145-3156, ISSN 1543-8384
Éditeur: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.9b00360

VHH-Photosensitizer Conjugates for Targeted Photodynamic Therapy of Met-Overexpressing Tumor Cells

Auteurs: Raimond Heukers, Vida Mashayekhi, Mercedes Ramirez-Escudero, Hans de Haard, Theo Verrips, Paul. van Bergen en Henegouwen, Sabrina Oliveira
Publié dans: Antibodies, Numéro 8/2, 2019, Page(s) 26, ISSN 2073-4468
Éditeur: MDPI
DOI: 10.3390/antib8020026

Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy

Auteurs: Else Driehuis, Sacha Spelier, Irati Beltrán Hernández, Remco de Bree, Stefan M. Willems, Hans Clevers, Sabrina Oliveira
Publié dans: Journal of Clinical Medicine, Numéro 8/11, 2019, Page(s) 1880, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm8111880

Preclinical and Clinical Evidence of Immune Responses Triggered in Oncologic Photodynamic Therapy: Clinical Recommendations

Auteurs: Beltrán Hernández, Yu, Ossendorp, Korbelik, Oliveira
Publié dans: Journal of Clinical Medicine, Numéro 9/2, 2020, Page(s) 333, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9020333

Nanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session

Auteurs: Marion M. Deken, Marta M. Kijanka, Irati Beltrán Hernández, Maxime D. Slooter, Henriette S. de Bruijn, Paul J. van Diest, Paul M.P. van Bergen en Henegouwen, Clemens W.G.M. Lowik, Dominic J. Robinson, Alexander L. Vahrmeijer, Sabrina Oliveira
Publié dans: Journal of Controlled Release, Numéro 323, 2020, Page(s) 269-281, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2020.04.030

Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging

Auteurs: Henriette S. de Bruijn, Vida Mashayekhi, Tom J.L. Schreurs, Pieter B.A.A. van Driel, Gustav J. Strijkers, Paul J. van Diest, Clemens W.G.M. Lowik, Ann L.B. Seynhaeve, Timo L.M. ten Hagen, Jeanine J. Prompers, Paul M.P. van Bergen en Henegouwen, Dominic J. Robinson, Sabrina Oliveira
Publié dans: Theranostics, Numéro 10/5, 2020, Page(s) 2436-2452, ISSN 1838-7640
Éditeur: Ivyspring International Publisher
DOI: 10.7150/thno.37949

The Potential of Nanobody-Targeted Photodynamic Therapy to Trigger Immune Responses

Auteurs: Irati Beltrán Hernández, Mathieu L. Angelier, Tommaso Del Buono D’Ondes, Alessia Di Maggio, Yingxin Yu, Sabrina Oliveira
Publié dans: Cancers, Numéro 12/4, 2020, Page(s) 978, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12040978

Vascular targeted photodynamic therapy: A review of the efforts towards molecular targeting of tumor vasculature

Auteurs: Vida Mashayekhi, Charlotte Op 't Hoog, Sabrina Oliveira
Publié dans: Journal of Porphyrins and Phthalocyanines, Numéro 23/11n12, 2019, Page(s) 1229-1240, ISSN 1088-4246
Éditeur: Society of Porphyrins and Phthalocyanines
DOI: 10.1142/s1088424619300180

Molecular targets for anticancer therapies in companion animals and humans: what can we learn from each other?

Auteurs: Irati Beltrán Hernández, Jannes Z. Kromhout, Erik Teske, Wim E. Hennink, Sebastiaan A. van Nimwegen, Sabrina Oliveira
Publié dans: Theranostics, 2021, ISSN 1838-7640
Éditeur: Ivyspring International Publisher
DOI: 10.7150/thno.55760