Publicaciones Peer reviewed articles (41) A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection Autores: Fourati S*, Talla A*, Mahmoudian M*, Burkhart JG*, Klén R*, Henao R, Yu T, Aydın Z, Yeung KY, Ahsen ME, Almugbel R, Jahandideh S, Liang X, Nordling TEM, Shiga M, Stanescu A, Vogel R, The Respiratory Viral DREAM Challenge Consortium, Pandey G, Chiu C, McClain MT, Woods CW, Ginsburg GS, Elo LL, Tsalik EL, Mangravite LM, Sieberts SK Publicado en: Nature Communications, 2018, ISSN 2041-1723 Editor: Nature Publishing Group DOI: 10.1038/s41467-018-06735-8 Stable Iterative Variable Selection. Autores: Mehrad Mahmoudian; Mehrad Mahmoudian; Mikko S. Venäläinen; Riku Klén; Laura L. Elo; Laura L. Elo Publicado en: Bioinformatics, Edición 15, 2021, ISSN 1367-4803 Editor: Oxford University Press DOI: 10.1093/bioinformatics/btab501 Improved risk prediction of chemotherapy-induced neutropenia – model development and validation with real-world data Autores: Venäläinen MS, Heervä E, Hirvonen O, Saraei S, Suomi T, Mikkola T, Bärlund M, Jyrkkiö S, Laitinen T, Elo LL Publicado en: Cancer Medicine, 2022, ISSN 2045-7634 Editor: John Wiley & Sons DOI: 10.1002/cam4.4465 Persistent coxsackievirus B1 inciencefection results in extensive changes in the transcriptome of a pancreatic cell line Autores: Buchacher T, Honkimaa A, Välikangas T, Lietzén N, Hirvonen K, Laiho JE, Sioofy-Khojine AB, Eskelinen EL, Hyöty H, Elo LL, Lahesmaa R Publicado en: iScience, 2021, ISSN 2589-0042 Editor: Cell Press Elsevier Inc. DOI: 10.1016/j.isci.2021.103653 Integrative omics approaches provide biological and clinical insights: examples from mitochondrial diseases Autores: Sofia Khan, Gulayse Ince-Dunn, Anu Suomalainen, Laura L Elo Publicado en: The Journal of Clinical Investigation, 2020, ISSN 0021-9738 Editor: American Society for Clinical Investigation DOI: 10.1172/jci129202 Computational deconvolution to estimate cell type-specific gene expression from bulk data Autores: Jaakkola MK, Elo LL. Publicado en: NAR Genomics and Bioinformatics, 2021, ISSN 2631-9268 Editor: Oxford University Press DOI: 10.1093/nargab/lqaa110 Community Assessment of the Predictability of Cancer Protein and Phosphoprotein Levels from Genomics and Transcriptomics Autores: Mi Yang , Francesca Petralia , Zhi Li, Hongyang Li, Weiping Ma, Xiaoyu Song, Sunkyu Kim, Heewon Lee, Han Yu, Bora Lee , Seohui Bae , Eunji Heo, Jan Kaczmarczyk, Piotr Stępniak, Michał Warchoł, Thomas Yu, Anna P Calinawan, Paul C Boutros, Samuel H Payne, Boris Reva, NCI-CPTAC-DREAM Consortium; Emily Boja, Henry Rodriguez, Gustavo Stolovitzky, Yuanfang Guan, Jaewoo Kang, Pei Wang, David Fenyö, J Publicado en: Cell Systems, 2020, ISSN 2405-4720 Editor: Cell Press DOI: 10.1016/j.cels.2020.06.013 A DREAM Challenge to build prediction models for short-term discontinuation of docetaxel in metastatic castration-resistant prostate cancer Autores: Seyednasrollah F*, Koestler DC*, Wang T*, Piccolo SR, Vega R, Greiner R, Fuchs C, Gofer E, Kumar L, Wolfinger RD, Winner KK, Bare C, Neto EC, Yu T, Shen L, Abdallah K, Norman T, Stolovitzky G, PCC-DREAM Community, Soule H, Sweeney CJ, Ryan CJ, Scher HI, Sartor O, Elo LL*, Zhou FL*, Guinney J*, Costello JC* Publicado en: JCO Clinical Cancer Informatics, 2017, ISSN 2473-4276 Editor: American Society of Clinical Oncology DOI: 10.1200/cci.17.00018 CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling Autores: Mohd Moin Khan, Ubaid Ullah, Meraj H. Khan, Lingjia Kong, Robert Moulder, Tommi Välikangas, Santosh Dilip Bhosale, Elina Komsi, Omid Rasool, Zhi Chen, Laura L. Elo, Jukka Westermarck, Riitta Lahesmaa Publicado en: iScience, Edición 23/3, 2020, Página(s) 100947, ISSN 2589-0042 Editor: Cell Press DOI: 10.1016/j.isci.2020.100947 Deep learning tools are top performers in long non-coding RNA prediction Autores: Tea Ammunét; Ning Wang; Sofia Khan; Laura L Elo Publicado en: Briefings in Functional Genomics, Edición 1, 2022, ISSN 2041-2649 Editor: Oxford University Press DOI: 10.1093/bfgp/elab045 Longitudinal modeling of ultrasensitive and traditional prostate-specific antigen and prediction of biochemical recurrence after radical prostatectomy Autores: Laajala TD*, Seikkula H*, Seyednasrollah F, Mirtti T, Boström PJ, Elo LL. Publicado en: Scientific Reports, 2016, ISSN 2045-2322 Editor: Nature Publishing Group DOI: 10.1038/srep36161 Introducing untargeted data-independent acquisition for metaproteomics of complex microbial samples Autores: Pietilä S*, Suomi T*, Elo LL Publicado en: ISME Communications, 2022, ISSN 2730-6151 Editor: Springer Nature DOI: 10.1101/2020.12.21.423800 Estimating cell type-specific differential expression using deconvolution. Autores: Maria K. Jaakkola; Laura L. Elo; Laura L. Elo Publicado en: Briefings in Bioinformatics, Edición 15, 2022, ISSN 1467-5463 Editor: Oxford University Press DOI: 10.1093/bib/bbab433 SimPhospho: a software tool enabling confident phosphosite assignment Autores: Suni V, Suomi T, Tsubosaka T, Imanishi SY, Elo LL, Corthals GL Publicado en: Bioinformatics, 2018, ISSN 1367-4803 Editor: Oxford University Press DOI: 10.1093/bioinformatics/bty151 Complex Interplay Between MAZR and Runx3 Regulates the Generation of Cytotoxic T Lymphocyte and Memory T Cells. Autores: Alexandra Franziska Gülich; Ramona Rica; Caroline Tizian; C. Viczenczova; Kseniya Khamina; Thomas Faux; Daniela Hainberger; Thomas Penz; Rémy Bosselut; Christoph Bock; Christoph Bock; Asta Laiho; Laura L. Elo; Andreas Bergthaler; Wilfried Ellmeier; Shinya Sakaguchi Publicado en: Frontiers in Immunology, Edición 1, 2021, ISSN 1664-3224 Editor: Frontiers Media S.A. DOI: 10.3389/fimmu.2021.535039 Development of Preoperative Risk Prediction Models for Short-Term Revision and Death Following Total Hip Arthroplasty Using data from the Finnish Arthroplasty Register Autores: Venäläinen MS, Panula VJ, Klén R, Haapakoski JJ, Eskelinen AP, Manninen MJ, Kettunen JS, Puhto AP, Vasara AI, Mäkelä KT, Elo LL Publicado en: JB JS Open Access, 2021, ISSN 2472-7245 Editor: The Journal of Bone and Joint Surgery Inc. DOI: 10.2106/jbjs.oa.20.00091 Umbilical Cord Blood DNA Methylation in Children Who Later Develop Type 1 Diabetes Autores: Laajala E, Ullah U, Grönroos T, Rasool O, Halla-aho V, Konki M, Kattelus R, Mykkänen J, Nurmio M, Vähä-Mäkilä M, Kallionpää H, Lietzén N, Ghimire BR, Laiho A, Hyöty H, Elo LL, Ilonen J, Knip M, Lund RJ, Orešič M, Veijola R, Lähdesmäki H, Toppari J, Lahesmaa R Publicado en: Diabetologia, 2022, ISSN 1432-0428 Editor: Springer DOI: 10.1007/s00125-022-05726-1 A comprehensive evaluation of popular proteomics software workflows for label-free proteome quantification and imputation Autores: Tommi Välikangas, Tomi Suomi, Laura L. Elo Publicado en: Briefings in Bioinformatics, 2017, ISSN 1467-5463 Editor: Oxford University Press DOI: 10.1093/bib/bbx054 A systematic evaluation of normalization methods in quantitative label-free proteomics Autores: Tommi Välikangas, Tomi Suomi, Laura L. Elo Publicado en: Briefings in Bioinformatics, 2018, Página(s) bbw095, ISSN 1467-5463 Editor: Oxford University Press DOI: 10.1093/bib/bbw095 Phosphonormalizer: an R package for normalization of MS-based label-free phosphoproteomics Autores: Sohrab Saraei, Tomi Suomi, Otto Kauko, Laura L Elo Publicado en: Bioinformatics, 2017, ISSN 1367-4803 Editor: Oxford University Press DOI: 10.1093/bioinformatics/btx573 Enterovirus-associated changes in blood transcriptomic profiles of children with genetic susceptibility to type 1 diabetes Autores: Niina Lietzen, Le T. T. An, Maria K. Jaakkola, Henna Kallionpää, Sami Oikarinen, Juha Mykkänen, Mikael Knip, Riitta Veijola, Jorma Ilonen, Jorma Toppari, Heikki Hyöty, Riitta Lahesmaa, Laura L. Elo Publicado en: Diabetologia, Edición 61/2, 2018, Página(s) 381-388, ISSN 0012-186X Editor: Springer Verlag DOI: 10.1007/s00125-017-4460-7 Prediction of Adulthood Obesity Using Genetic and Childhood Clinical Risk Factors in the Cardiovascular Risk in Young Finns StudyCLINICAL PERSPECTIVE Autores: Fatemeh Seyednasrollah, Johanna Mäkelä, Niina Pitkänen, Markus Juonala, Nina Hutri-Kähönen, Terho Lehtimäki, Jorma Viikari, Tanika Kelly, Changwei Li, Lydia Bazzano, Laura L. Elo, Olli T. Raitakari Publicado en: Circulation: Cardiovascular Genetics, Edición 10/3, 2017, Página(s) e001554, ISSN 1942-3268 Editor: Lippincott Williams & Wilkins Ltd. DOI: 10.1161/CIRCGENETICS.116.001554 PASI: A novel pathway method to identify delicate group effects Autores: Maria K. Jaakkola, Aidan J. McGlinchey, Riku Klén, Laura L. Elo Publicado en: PLOS ONE, Edición 13/7, 2018, Página(s) e0199991, ISSN 1932-6203 Editor: Public Library of Science DOI: 10.1371/journal.pone.0199991 Transcriptional Repressor HIC1 Contributes to Suppressive Function of Human Induced Regulatory T Cells Autores: Ubaid Ullah, Syed Bilal Ahmad Andrabi, Subhash Kumar Tripathi, Obaiah Dirasantha, Kartiek Kanduri, Sini Rautio, Catharina C. Gross, Sari Lehtimäki, Kanchan Bala, Johanna Tuomisto, Urvashi Bhatia, Deepankar Chakroborty, Laura L. Elo, Harri Lähdesmäki, Heinz Wiendl, Omid Rasool, Riitta Lahesmaa Publicado en: Cell Reports, Edición 22/8, 2018, Página(s) 2094-2106, ISSN 2211-1247 Editor: Cell Press DOI: 10.1016/j.celrep.2018.01.070 Enhanced differential expression statistics for data-independent acquisition proteomics Autores: Tomi Suomi, Laura L. Elo Publicado en: Scientific Reports, Edición 7/1, 2017, ISSN 2045-2322 Editor: Nature Publishing Group DOI: 10.1038/s41598-017-05949-y ROTS: An R package for reproducibility-optimized statistical testing Autores: Tomi Suomi, Fatemeh Seyednasrollah, Maria K. Jaakkola, Thomas Faux, Laura L. Elo Publicado en: PLOS Computational Biology, Edición 13/5, 2017, Página(s) e1005562, ISSN 1553-7358 Editor: Public Library of Science DOI: 10.1371/journal.pcbi.1005562 Quantitative Proteomics Reveals the Dynamic Protein Landscape during Initiation of Human Th17 Cell Polarization Autores: Subhash K. Tripathi, Tommi Välikangas, Ankitha Shetty, Mohd Moin Khan, Robert Moulder, Santosh D. Bhosale, Elina Komsi, Verna Salo, Rafael Sales De Albuquerque, Omid Rasool, Sanjeev Galande, Laura L. Elo, Riitta Lahesmaa Publicado en: iScience, Edición 11, 2019, Página(s) 334-355, ISSN 2589-0042 Editor: Cell Press DOI: 10.1016/j.isci.2018.12.020 A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation Autores: Shetty A*, Tripathi SK*, Junttila S*, Buchacher T*, Biradar R, Bhosale SD, Envall T, Laiho A, Moulder R, Rasool O, Galande S, Elo LL*, Lahesmaa R* Publicado en: Nucleic Acids Research, 2022, ISSN 1362-4962 Editor: Oxford University Press DOI: 10.1093/nar/gkac256 Likelihood contrasts: a machine learning algorithm for binary classification of longitudinal data Autores: Riku Klén, Markku Karhunen, Laura L. Elo Publicado en: Scientific Reports, Edición 10/1, 2020, ISSN 2045-2322 Editor: Nature Publishing Group DOI: 10.1038/s41598-020-57924-9 Weight loss trajectories in the Healthy Weight Coaching - a real-life web-based obesity management program Autores: Kupila S, Venäläinen MS, Suojanen LL, Rosengård-Bärlund M, Ahola AJ, Elo LL, Pietiläinen KH Publicado en: JMIR Formative Research, 2022, ISSN 2561-326X Editor: JMIR Publications DOI: 10.2196/26374 How reliable are trial-based prognostic models in real-world patients with metastatic castration resistant prostate cancer? Autores: Seyednasrollah F, Mahmoudian M, Rautakorpi L, Hirvonen O, Laitinen T, Jyrkkiö S, Elo LL Publicado en: Euporean Urology, 2017, ISSN 0302-2838 Editor: Elsevier BV DOI: 10.1016/j.eururo.2017.01.043 Predicting Skeletal Muscle and Whole-Body Insulin Sensitivity Using NMR-Metabolomic Profiling Autores: Riku Klén, Miikka-Juhani Honka, Jarna C Hannukainen, Ville Huovinen, Marco Bucci, Aino Latva-Rasku, Mikko S Venäläinen, Kari K Kalliokoski, Kirsi A Virtanen, Riikka Lautamäki, Patricia Iozzo, Laura L Elo, Pirjo Nuutila Publicado en: Journal of the Endocrine Society, Edición 4/4, 2020, ISSN 2472-1972 Editor: Oxford Academic Journals DOI: 10.1210/jendso/bvaa026 Differential ATAC-seq and ChIP-seq peak detection using ROTS. Autores: Thomas Faux; Kalle T Rytkönen; Mehrad Mahmoudian; Niklas Paulin; Sini Junttila; Asta Laiho; Laura L. Elo Publicado en: NAR Genomics and Bioinformatics, Edición 1, 2021, ISSN 2631-9268 Editor: Oxford University Press DOI: 10.1093/nargab/lqab059 PhosPiR: An automated phosphoproteomic pipeline in R Autores: Hong Y, Flinkman D, Suomi T, Pietilä S, James P, Coffey E, Elo LL Publicado en: Briefings in Bioinformatics, 2022, ISSN 1467-5463 Editor: Oxford University Press DOI: 10.1093/bib/bbab510 Serum Proteomic Profiling to Identify Biomarkers of Premature Carotid Atherosclerosis Autores: Bhosale SD, Moulder R, Venäläinen MS, Koskinen JS, Pitkänen N, Juonala MT, Kähönen MAP, Lehtimäki TJ, Viikari JSA, Elo LL, Goodlett RD, Lahesmaa R, Raitakari OT. Publicado en: Sci Rep, 2018, ISSN 2045-2322 Editor: Nature Publishing Group DOI: 10.1038/s41598-018-27265-9 Pancreas whole tissue transcriptomics highlights the role of the exocrine pancreas in patients with recently diagnosed type 1 diabetes Autores: Välikangas T*, Lietzén N*, Jaakkola MK, Krogvold L, Eike MC, Kallionpää H, Tuomela S, Mathews C, Gerling IC, Oikarinen S, Hyöty H, Dahl-Jorgensen K, Elo LL*, Lahesmaa R* Publicado en: Frontiers in Endocrinology, 2022, ISSN 1664-2392 Editor: Frontiers Media DOI: 10.3389/fendo.2022.861985 Easy-to-use tool for evaluating the elevated acute kidney injury risk against reduced cardiovascular disease risk during intensive blood pressure control Autores: Mikko S. Venäläinen, Riku Klén, Mehrad Mahmoudian, Olli T. Raitakari, Laura L. Elo Publicado en: Journal of Hypertension, Edición 38/3, 2020, Página(s) 511-518, ISSN 0263-6352 Editor: Lippincott Williams & Wilkins Ltd. DOI: 10.1097/hjh.0000000000002282 Early DNA methylation changes in children developing beta cell autoimmunity at a young age Autores: Starskaia I, Laajala E, Grönroos T, Härkönen T, Junttila S, Kattelus R, Kallionpää H, Laiho A, Suni V, Tilmann V, Lund R, Elo LL, Lähdesmäki H, Knip M, Ullah U, Lahesmaa R Publicado en: Diabetologia, 2022, ISSN 1432-0428 Editor: Springer DOI: 10.1007/s00125-022-05657-x Protein interactome of the Cancerous Inhibitor of protein phosphatase 2A (CIP2A) in Th17 cells Autores: Mohd Moin Khan, Tommi Välikangas, Meraj Hasan Khan, Robert Moulder, Ubaid Ullah, Santosh Dilip Bhosale, Elina Komsi, Umar Butt, Xi Qiao, Jukka Westermarck, Laura L. Elo, Riitta Lahesmaa Publicado en: Current Research in Immunology, Edición 1, 2020, Página(s) 10-22, ISSN 2590-2555 Editor: Cell Press DOI: 10.1016/j.crimmu.2020.02.001 Type 1 Diabetes in Children With Genetic Risk May Be Predicted Very Early With a Blood miRNA Autores: Suomi T*, Kalim UU*, Rasool O, Laiho A, Kallionpää H, Vähä-Mäkilä M, Nurmio M, Mykkänen J, Härkönen T, Hyöty H, Ilonen J, Veijola R, Toppari J, Knip M, Elo LL*, Lahesmaa R* Publicado en: Diabetes Care, 2022, ISSN 0149-5992 Editor: American Diabetes Association DOI: 10.2337/dc21-2120 Statistical and machine learning methods to study human CD4+ T cell proteome profiles Autores: Suomi T, Elo LL Publicado en: Immunology Letters, 2022, ISSN 0165-2478 Editor: Elsevier BV DOI: 10.1016/j.imlet.2022.03.006 Book chapters (1) A Data Analysis Protocol for Quantitative Data-Independent Acquisition Proteomics. Autores: Pietilä S, Suomi T, Aakko J, Elo LL Publicado en: Functional Proteomics: Methods in Molecular Biology, 2019, ISBN 978-1-4939-8813-6 Editor: Humana New York, NY DOI: 10.1007/978-1-4939-8814-3_27 Other (2) Longitudinal analysis of pathway deregulation using structural information with case studies in early type 1 diabetes Autores: Jaakkola MK, Suomi T, Kukkonen-Macchi A, Elo LL. Publicado en: bioRxiv, 2022 Editor: bioRxiv DOI: 10.1101/2022.06.21.497110 Enhanced longitudinal differential expression detection in proteomics with robust reproducibility optimization regression. Autores: Välikangas T, Suomi T, Chandler CE, Scott AJ, Tran BQ, Ernst RK, Goodlett DR, Elo LL Publicado en: bioRxiv, 2022 Editor: bioRxiv DOI: 10.1101/2021.04.19.440388 Buscando datos de OpenAIRE... Se ha producido un error en la búsqueda de datos de OpenAIRE No hay resultados disponibles
