Therapeutic and Biomarker Potential of long non-coding RNAs in Vascular Disease

Project Information

NORVAS

Grant agreement ID: 679777

DOI 10.3030/679777

Project closed

EC signature date 6 April 2016

Start date 1 May 2016

End date 30 April 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 493 125,00

EU contribution € 1 493 125,00

Coordinated by

KAROLINSKA INSTITUTET
Sweden

Publications

Peer reviewed articles (11)

Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility

Author(s): Albert Busch, Jessica Pauli, Greg Winski, Sonja Bleichert, Ekaterina Chernogubova, Susanne Metschl, Hanna Winter, Matthias Trenner, Armin Wiegering, Christoph Otto, Johannes Fischer, Judith Reiser, Julia Werner, Joy Roy, Christine Brostjan, Christoph Knappich, Hans-Henning Eckstein, Valentina Paloschi, Lars Maegdefessel
Published in: JCI Insight, 2021, ISSN 2379-3708
Publisher: JCI
DOI: 10.1172/jci.insight.140364

Involvement of Myeloid Cells and Noncoding RNA in Abdominal Aortic Aneurysm Disease

Author(s): Christoph Knappich, Joshua M. Spin, Hans-Henning Eckstein, Philip S. Tsao, Lars Maegdefessel
Published in: Antioxidants & Redox Signaling, Issue 33/9, 2020, Page(s) 602-620, ISSN 1523-0864
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ars.2020.8035

Non-coding RNAs in cardiovascular cell biology and atherosclerosis

Author(s): Francesca Fasolo, Karina Di Gregoli, Lars Maegdefessel, Jason L Johnson
Published in: Cardiovascular Research, Issue 115/12, 2019, Page(s) 1732-1756, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvz203

Non-coding RNAs: key regulators of smooth muscle cell fate in vascular disease

Author(s): Nicholas J Leeper, Lars Maegdefessel
Published in: Cardiovascular Research, Issue 114/4, 2017, Page(s) 611-621, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvx249

H19 Induces Abdominal Aortic Aneurysm Development and Progression

Author(s): Daniel Y. Li, Albert Busch, Hong Jin, Ekaterina Chernogubova, Jaroslav Pelisek, Joakim Karlsson, Bengt Sennblad, Shengliang Liu, Shen Lao, Patrick Hofmann, Alexandra Bäcklund, Suzanne M. Eken, Joy Roy, Per Eriksson, Brian Dacken, Deepak Ramanujam, Anne Dueck, Stefan Engelhardt, Reinier A. Boon, Hans-Henning Eckstein, Joshua M. Spin, Philip S. Tsao, Lars Maegdefessel
Published in: Circulation, Issue 138/15, 2018, Page(s) 1551-1568, ISSN 0009-7322
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCULATIONAHA.117.032184

Non-coding RNA Contribution to Thoracic and Abdominal Aortic Aneurysm Disease Development and Progression

Author(s): Yuhuang Li, Lars Maegdefessel
Published in: Frontiers in Physiology, Issue 8, 2017, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2017.00429

Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm

Author(s): Antonio Di Gennaro, Ana Carolina Araújo, Albert Busch, Hong Jin, Dick Wågsäter, Emina Vorkapic, Kenneth Caidahl, Per Eriksson, Bengt Samuelsson, Lars Maegdefessel, Jesper Z. Haeggström
Published in: Proceedings of the National Academy of Sciences, Issue 115/8, 2018, Page(s) 1907-1912, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1717906115

Role of Noncoding RNAs in the Pathogenesis of Abdominal Aortic Aneurysm

Author(s): Sandeep Kumar, Reinier A. Boon, Lars Maegdefessel, Stefanie Dimmeler, Hanjoong Jo
Published in: Circulation Research, Issue 124/4, 2019, Page(s) 619-630, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.118.312438

miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease

Author(s): Suzanne M. Eken, Tinna Christersdottir, Greg Winski, Traimate Sangsuwan, Hong Jin, Ekaterina Chernogubova, John Pirault, Changyan Sun, Nancy Simon, Hanna Winter, Alexandra Backlund, Siamak Haghdoost, Göran K. Hansson, Martin Halle, Lars Maegdefessel
Published in: JACC: Basic to Translational Science, Issue 4/1, 2019, Page(s) 72-82, ISSN 2452-302X
Publisher: Elsevier
DOI: 10.1016/j.jacbts.2018.10.006

Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases

Author(s): Valentina Paloschi, Maria Sabater-Lleal, Heleen Middelkamp, Aisen Vivas, Sofia Johansson, Andries van der Meer, Maria Tenje, Lars Maegdefessel
Published in: Cardiovascular Research, 2021, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvab088

Long noncoding RNAs in key cellular processes involved in aortic aneurysms

Author(s): Zhi-yuan Wu, Matthias Trenner, Reinier A. Boon, Joshua M. Spin, Lars Maegdefessel
Published in: Atherosclerosis, Issue 292, 2020, Page(s) 112-118, ISSN 0021-9150
Publisher: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2019.11.013