Therapeutic and Biomarker Potential of long non-coding RNAs in Vascular Disease

Informazioni relative al progetto

NORVAS

ID dell’accordo di sovvenzione: 679777

DOI 10.3030/679777

Progetto chiuso

Data della firma CE 6 Aprile 2016

Data di avvio 1 Maggio 2016

Data di completamento 30 Aprile 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 493 125,00

Contributo UE € 1 493 125,00

Coordinato da

KAROLINSKA INSTITUTET
Sweden

Pubblicazioni

Peer reviewed articles (11)

Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility

Autori: Albert Busch, Jessica Pauli, Greg Winski, Sonja Bleichert, Ekaterina Chernogubova, Susanne Metschl, Hanna Winter, Matthias Trenner, Armin Wiegering, Christoph Otto, Johannes Fischer, Judith Reiser, Julia Werner, Joy Roy, Christine Brostjan, Christoph Knappich, Hans-Henning Eckstein, Valentina Paloschi, Lars Maegdefessel
Pubblicato in: JCI Insight, 2021, ISSN 2379-3708
Editore: JCI
DOI: 10.1172/jci.insight.140364

Involvement of Myeloid Cells and Noncoding RNA in Abdominal Aortic Aneurysm Disease

Autori: Christoph Knappich, Joshua M. Spin, Hans-Henning Eckstein, Philip S. Tsao, Lars Maegdefessel
Pubblicato in: Antioxidants & Redox Signaling, Numero 33/9, 2020, Pagina/e 602-620, ISSN 1523-0864
Editore: Mary Ann Liebert Inc.
DOI: 10.1089/ars.2020.8035

Non-coding RNAs in cardiovascular cell biology and atherosclerosis

Autori: Francesca Fasolo, Karina Di Gregoli, Lars Maegdefessel, Jason L Johnson
Pubblicato in: Cardiovascular Research, Numero 115/12, 2019, Pagina/e 1732-1756, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvz203

Non-coding RNAs: key regulators of smooth muscle cell fate in vascular disease

Autori: Nicholas J Leeper, Lars Maegdefessel
Pubblicato in: Cardiovascular Research, Numero 114/4, 2017, Pagina/e 611-621, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvx249

H19 Induces Abdominal Aortic Aneurysm Development and Progression

Autori: Daniel Y. Li, Albert Busch, Hong Jin, Ekaterina Chernogubova, Jaroslav Pelisek, Joakim Karlsson, Bengt Sennblad, Shengliang Liu, Shen Lao, Patrick Hofmann, Alexandra Bäcklund, Suzanne M. Eken, Joy Roy, Per Eriksson, Brian Dacken, Deepak Ramanujam, Anne Dueck, Stefan Engelhardt, Reinier A. Boon, Hans-Henning Eckstein, Joshua M. Spin, Philip S. Tsao, Lars Maegdefessel
Pubblicato in: Circulation, Numero 138/15, 2018, Pagina/e 1551-1568, ISSN 0009-7322
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCULATIONAHA.117.032184

Non-coding RNA Contribution to Thoracic and Abdominal Aortic Aneurysm Disease Development and Progression

Autori: Yuhuang Li, Lars Maegdefessel
Pubblicato in: Frontiers in Physiology, Numero 8, 2017, ISSN 1664-042X
Editore: Frontiers Research Foundation
DOI: 10.3389/fphys.2017.00429

Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm

Autori: Antonio Di Gennaro, Ana Carolina Araújo, Albert Busch, Hong Jin, Dick Wågsäter, Emina Vorkapic, Kenneth Caidahl, Per Eriksson, Bengt Samuelsson, Lars Maegdefessel, Jesper Z. Haeggström
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 115/8, 2018, Pagina/e 1907-1912, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1717906115

Role of Noncoding RNAs in the Pathogenesis of Abdominal Aortic Aneurysm

Autori: Sandeep Kumar, Reinier A. Boon, Lars Maegdefessel, Stefanie Dimmeler, Hanjoong Jo
Pubblicato in: Circulation Research, Numero 124/4, 2019, Pagina/e 619-630, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.118.312438

miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease

Autori: Suzanne M. Eken, Tinna Christersdottir, Greg Winski, Traimate Sangsuwan, Hong Jin, Ekaterina Chernogubova, John Pirault, Changyan Sun, Nancy Simon, Hanna Winter, Alexandra Backlund, Siamak Haghdoost, Göran K. Hansson, Martin Halle, Lars Maegdefessel
Pubblicato in: JACC: Basic to Translational Science, Numero 4/1, 2019, Pagina/e 72-82, ISSN 2452-302X
Editore: Elsevier
DOI: 10.1016/j.jacbts.2018.10.006

Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases

Autori: Valentina Paloschi, Maria Sabater-Lleal, Heleen Middelkamp, Aisen Vivas, Sofia Johansson, Andries van der Meer, Maria Tenje, Lars Maegdefessel
Pubblicato in: Cardiovascular Research, 2021, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvab088

Long noncoding RNAs in key cellular processes involved in aortic aneurysms

Autori: Zhi-yuan Wu, Matthias Trenner, Reinier A. Boon, Joshua M. Spin, Lars Maegdefessel
Pubblicato in: Atherosclerosis, Numero 292, 2020, Pagina/e 112-118, ISSN 0021-9150
Editore: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2019.11.013