CDK6 in transcription - turning a foe in a friend | CDK6-DrugOpp | Project | Results | H2020 | CORDIS

Pubblicazioni

Autori: Sofie Nebenfuehr, Karoline Kollmann, Veronika Sexl
Pubblicato in: International Journal of Cancer, Numero 147/11, 2020, Pagina/e 2988-2995, ISSN 0020-7136
Editore: John Wiley & Sons Inc.
DOI: 10.1002/ijc.33054

CDK6 Degradation Is Counteracted by p16INK4A and p18INK4C in AML

Autori: Belinda S. Schmalzbauer; Teresemary Thondanpallil; Gerwin Heller; Alessia Schirripa; Clio-Melina Sperl; Isabella M. Mayer; Vanessa M. Knab; Sofie Nebenfuehr; Markus Zojer; André C. Mueller; Frédéric Fontaine; Thorsten Klampfl; Veronika Sexl; Karoline Kollmann
Pubblicato in: Cancers (Basel), Numero 20726694, 2022, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14061554

Isolation, Maintenance and Expansion of Adult Hematopoietic Stem/Progenitor Cells and Leukemic Stem Cells

Autori: Isabella Maria Mayer; Andrea Hoelbl-Kovacic; Veronika Sexl; Eszter Doma
Pubblicato in: Cancers (Basel), Numero 20726694, 2022, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14071723

A robust approach for the generation of functional hematopoietic progenitor cell lines to model leukemic transformation

Autori: Eszter Doma, Isabella Maria Mayer, Tania Brandstoetter, Barbara Maurer, Reinhard Grausenburger, Ingeborg Menzl, Markus Zojer, Andrea Hoelbl-Kovacic, Leif Carlsson, Gerwin Heller, Karoline Kollmann, Veronika Sexl
Pubblicato in: Blood Advances, Numero 5/1, 2021, Pagina/e 39-53, ISSN 2473-9529
Editore: American Society of Hematology
DOI: 10.1182/bloodadvances.2020003022

The interplay of CDK4 and CDK6 in melanoma

Autori: Karoline Kollmann, Coralie Briand, Florian Bellutti, Nikolaus Schicher, Stefan Blunder, Markus Zojer, Christoph Hoeller
Pubblicato in: Oncotarget, Numero 10/14, 2019, Pagina/e 1346-1359, ISSN 1949-2553
Editore: Impact Journals
DOI: 10.18632/oncotarget.26515

Inducible deletion of CDK4 and CDK6 - deciphering CDK4/6 inhibitor effects in the hematopoietic system

Autori: Barbara Maurer, Tania Brandstoetter, Sebastian Kollmann, Veronika Sexl, Michaela Prchal-Murphy
Pubblicato in: Haematologica, 2020, Pagina/e haematol.2020.256313, ISSN 0390-6078
Editore: Ferrata Storti Foundation
DOI: 10.3324/haematol.2020.256313

CDK4/6 and MAPK—Crosstalk as Opportunity for Cancer Treatment

Autori: Lisa Scheiblecker, Karoline Kollmann, Veronika Sexl
Pubblicato in: Pharmaceuticals, Numero 13/12, 2020, Pagina/e 418, ISSN 1424-8247
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ph13120418

CDK6 Inhibition: A Novel Approach in AML Management

Autori: Iris Z. Uras, Veronika Sexl, Karoline Kollmann
Pubblicato in: International Journal of Molecular Sciences, Numero 21/7, 2020, Pagina/e 2528, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21072528

Cdk6 contributes to cytoskeletal stability in erythroid cells

Autori: Iris Z. Uras, Ruth M. Scheicher, Karoline Kollmann, Martin Glösmann, Michaela Prchal-Murphy, Anca S. Tigan, Daniela A. Fux, Sandro Altamura, Joana Neves, Martina U. Muckenthaler, Keiryn L. Bennett, Stefan Kubicek, Philip W. Hinds, Marieke von Lindern, Veronika Sexl
Pubblicato in: Haematologica, Numero 102/6, 2017, Pagina/e 995-1005, ISSN 0390-6078
Editore: Ferrata Storti Foundation
DOI: 10.3324/haematol.2016.159947

p27 in FLT3-driven acute myeloid leukemia: many roads lead to ruin

Autori: Iris Z Uras, Florian Bellutti, Veronika Sexl
Pubblicato in: Haematologica, Numero 102/8, 2017, Pagina/e 1299-1301, ISSN 0390-6078
Editore: Ferrata Storti Foundation
DOI: 10.3324/haematol.2017.171819

Cdk6: At the interface of Rb and p53

Autori: Sofie Nebenfuehr, Florian Bellutti, Veronika Sexl
Pubblicato in: Molecular & Cellular Oncology, Numero 5/5, 2018, Pagina/e e1511206, ISSN 2372-3556
Editore: Taylor & Francis
DOI: 10.1080/23723556.2018.1511206

CDK6 Antagonizes p53-Induced Responses during Tumorigenesis

Autori: Florian Bellutti, Anca-Sarmiza Tigan, Sofie Nebenfuehr, Marlies Dolezal, Markus Zojer, Reinhard Grausenburger, Svenja Hartenberger, Sebastian Kollmann, Eszter Doma, Michaela Prchal-Murphy, Iris Z. Uras, Alexander Höllein, Donna S. Neuberg, Benjamin L. Ebert, Anna Ringler, Andre C. Mueller, Joanna I. Loizou, Philip W. Hinds, Claus Vogl, Gerwin Heller, Stefan Kubicek, Johannes Zuber, Marcos Malumbr
Pubblicato in: Cancer Discovery, Numero 8/7, 2018, Pagina/e 884-897, ISSN 2159-8274
Editore: American Association for Cancer Research Inc.
DOI: 10.1158/2159-8290.CD-17-0912

CDK6 coordinates JAK2 V617F mutant MPN via NF-κB and apoptotic networks

Autori: Iris Z. Uras, Barbara Maurer, Harini Nivarthi, Philipp Jodl, Karoline Kollmann, Michaela Prchal-Murphy, Jelena D. Milosevic Feenstra, Markus Zojer, Sabine Lagger, Reinhard Grausenburger, Beatrice Grabner, Raimund Holly, Anoop Kavirayani, Christoph Bock, Heinz Gisslinger, Peter Valent, Robert Kralovics, Veronika Sexl
Pubblicato in: Blood, Numero 133/15, 2019, Pagina/e 1677-1690, ISSN 0006-4971
Editore: American Society of Hematology
DOI: 10.1182/blood-2018-08-872648

Therapeutic Vulnerabilities in FLT3-Mutant AML Unmasked by Palbociclib

Autori: Iris Uras, Barbara Maurer, Sofie Nebenfuehr, Markus Zojer, Peter Valent, Veronika Sexl
Pubblicato in: International Journal of Molecular Sciences, Numero 19/12, 2018, Pagina/e 3987, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms19123987

The Effect of CDK6 Expression on DNA Methylation and DNMT3B Regulation

Autori: Gerwin Heller, Sofie Nebenfuehr, Florian Bellutti, Huriye Ünal, Markus Zojer, Lisa Scheiblecker, Veronika Sexl, Karoline Kollmann
Pubblicato in: iScience, Numero 23/10, 2020, Pagina/e 101602, ISSN 2589-0042
Editore: Cell Press
DOI: 10.1016/j.isci.2020.101602

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CDK6 in transcription - turning a foe in a friend

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