Objective Tuberculosis (TB) remains a major global health problem with 9 million new TB cases and 1.5 million TB deaths in 2013.Given that with a wide health care access to diagnosis, most deaths are preventable, TB mortality is still unacceptably high.With TOPO-TB the aim is to develop the first rapid diagnostic kit based on detection of the activity of an essential enzyme ofthe bacteria. A high degree of simplicity and low cost, in combination with mycobacteria detection in non-sputum samples,will enable TOPO-TB to achieve high impact on Tuberculosis control and elimination. Importantly, the low resourceadaptable format meets the requirements of highly competitive TB test, complementing state-of-the-art methods for detectionat the point of care patient level. Fields of science medical and health scienceshealth sciencesinfectious diseasesmalariamedical and health sciencesbasic medicineimmunologymedical and health scienceshealth sciencesinfectious diseasesRNA virusesHIVmedical and health sciencesclinical medicinepneumologytuberculosisnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.3. - Treating and managing disease Topic(s) PHC-12-2015-1 - Clinical research for the validation of biomarkers and/or diagnostic medical devices Call for proposal H2020-SMEInst-2014-2015 See other projects for this call Sub call H2020-SMEINST-1-2015 Funding Scheme SME-1 - SME instrument phase 1 Coordinator ZYMONOSTICS APS Net EU contribution € 50 000,00 Address ABOGADE 15 8200 AARHUS N Denmark See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Danmark Midtjylland Østjylland Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 71 429,00