Imaging and detection of tumor-associated glycan structures on tumor cells

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Produce a project poster and a presentation
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Produce a minimum of 2 press releases

Publications

Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins

Auteurs: Lingbo Sun; Andriana Konstantinidi; Zilu Ye; Rebecca Nason; Yuecheng Zhang; Christian Büll; Barbro Kahl-Knutson; Lars Hansen; Hakon Leffler; Sergey Y. Vakhrushev; Zhang Yang; Henrik Clausen; Yoshiki Narimatsu
Publié dans: Journal of biological chemistry, Numéro Dec 24;298(2), 2021, Page(s) 1-14, ISSN 0021-9258
Éditeur: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2021.101382

Molecularly imprinted polymers in biological applications

Auteurs: Zahra El-Schich, Yuecheng Zhang, Marek Feith, Sarah Beyer, Louise Sternbæk, Lars Ohlsson, Maria Stollenwerk, Anette Gjörloff Wingren
Publié dans: BioTechniques, Numéro 69/6, 2020, Page(s) 406-419, ISSN 0736-6205
Éditeur: Eaton Publishing Co.
DOI: 10.2144/btn-2020-0091

Sialic Acid as a Biomarker Studied in Breast Cancer Cell Lines In Vitro Using Fluorescent Molecularly Imprinted Polymers

Auteurs: Zahra El-Schich, Yuecheng Zhang, Tommy Göransson, Nishtman Dizeyi, Jenny L. Persson, Emil Johansson, Remi Caraballo, Mikael Elofsson, Sudhirkumar Shinde, Börje Sellergren, Anette Gjörloff Wingren
Publié dans: Applied Sciences, Numéro 11/7, 2021, Page(s) 3256, ISSN 2076-3417
Éditeur: MDPI
DOI: 10.3390/app11073256

Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration‐resistant prostate cancer

Auteurs: Julius Semenas, Tianyan Wang, Azharuddin Sajid Syed Khaja, AKM Firoj Mahmud, Athanasios Simoulis, Thomas Grundström, Maria Fällman, Jenny L. Persson
Publié dans: Molecular Oncology, Numéro 15/4, 2021, Page(s) 968-986, ISSN 1574-7891
Éditeur: Elsevier BV
DOI: 10.1002/1878-0261.12873

Establishment of Prostate Tumor Growth and Metastasis Is Supported by Bone Marrow Cells and Is Mediated by PIP5K1α Lipid Kinase

Auteurs: Richard Karlsson, Per Larsson, Regina Miftakhova, Azharuddin Sajid Syed Khaja, Martuza Sarwar, Julius Semenas, Sa Chen, Andreas Hedblom, Tianyan Wang, Kristina Ekström-Holka, Athanasios Simoulis, Anjani Kumar, Niels Ødum, Thomas Grundström, Jenny L. Persson
Publié dans: Cancers, Numéro 12/9, 2020, Page(s) 2719, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12092719

Primary breast cancer biomarkers based on glycosylation and extracellular vesicles detected from human serum

Auteurs: Joonas Terävä, Alejandra Verhassel, Orsola Botti, Md. Khirul Islam, Janne Leivo, Saara Wittfooth, Pirkko Härkönen, Kim Pettersson, Kamlesh Gidwani
Publié dans: Cancer Reports, 2021, ISSN 2573-8348
Éditeur: Wiley Online Library
DOI: 10.1002/cnr2.1540

Imprinted Particles for Direct Fluorescence Detection of Sialic Acid in Polar Media and on Cancer Cells with Enhanced Control of Nonspecific Binding

Auteurs: Martha Kimani, Sarah Beyer, Zahra El-Schich, Kornelia Gawlitza, Anette Gjörloff-Wingren, Knut Rurack
Publié dans: ACS Applied Polymer Materials, Numéro 3/5, 2021, Page(s) 2363-2373, ISSN 2637-6105
Éditeur: ACS Publications
DOI: 10.1021/acsapm.0c01353

Quantitative characterization of O-GalNAc glycosylation

Auteurs: Tomislav Čaval, Noortje de Haan, Andriana Konstantinidi, Sergey Y Vakhrushev
Publié dans: Current Opinion in Structural Biology, Numéro 68, 2021, Page(s) 135-141, ISSN 0959-440X
Éditeur: Elsevier BV
DOI: 10.1016/j.sbi.2020.12.010

The GAGOme: a cell-based library of displayed glycosaminoglycans

Auteurs: Yen-Hsi Chen, Yoshiki Narimatsu, Thomas M. Clausen, Catarina Gomes, Richard Karlsson, Catharina Steentoft, Charlotte B. Spliid, Tobias Gustavsson, Ali Salanti, Andrea Persson, Anders Malmström, Daniel Willén, Ulf Ellervik, Eric P. Bennett, Yang Mao, Henrik Clausen, Zhang Yang
Publié dans: Nature Methods, Numéro 15/11, 2018, Page(s) 881-888, ISSN 1548-7091
Éditeur: Nature Publishing Group
DOI: 10.1038/s41592-018-0086-z

Determination of cytokine regulated glycan expression by using molecularly imprinted polymers targeting sialic acid

Auteurs: Yuecheng Zhang, Kushtrim Llapashtica, Sudhirkumar Shinde, Borje Sellergren, Zahra El-Schich, Anette Gjorloff Wingren
Publié dans: Journal of Cancer Metastasis and Treatment, Numéro 2019, 2019, ISSN 2454-2857
Éditeur: OAE Publishing Inc.
DOI: 10.20517/2394-4722.2018.112

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

Auteurs: Yoshiki Narimatsu, Hiren J. Joshi, Rebecca Nason, Julie Van Coillie, Richard Karlsson, Lingbo Sun, Zilu Ye, Yen-Hsi Chen, Katrine T. Schjoldager, Catharina Steentoft, Sanae Furukawa, Barbara A. Bensing, Paul M. Sullam, Andrew J. Thompson, James C. Paulson, Christian Büll, Gosse J. Adema, Ulla Mandel, Lars Hansen, Eric Paul Bennett, Ajit Varki, Sergey Y. Vakhrushev, Zhang Yang, Henrik Clausen
Publié dans: Molecular Cell, Numéro 75/2, 2019, Page(s) 394-407.e5, ISSN 1097-2765
Éditeur: Cell Press
DOI: 10.1016/j.molcel.2019.05.017

γ‐(S)‐Guanidinylmethyl Modified Triplex‐Forming Peptide Nucleic Acids Increase Hoogsteen‐Face Affinity for a MicroRNA and Enhance Cellular Uptake

Auteurs: Ville Tähtinen, Alejandra Verhassel, Johanna Tuomela, Pasi Markus Virta
Publié dans: ChemBioChem, 2019, ISSN 1439-4227
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201900393

Engineering mammalian cells to produce plant-specific N-glycosylation on proteins

Auteurs: Joachim Steen Larsen, Richard Torbjörn Gustav Karlsson, Weihua Tian, Morten Alder Schulz, Annemarie Matthes, Henrik Clausen, Bent Larsen Petersen, Zhang Yang
Publié dans: Glycobiology, 2020, ISSN 1460-2423
Éditeur: Glycobiology
DOI: 10.1093/glycob/cwaa009

The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer

Auteurs: Per Larsson, Azharuddin Sajid Syed Khaja, Julius Semenas, Tianyan Wang, Martuza Sarwar, Nishtman Dizeyi, Athanasios Simoulis, Andreas Hedblom, Sun Nyunt Wai, Niels Ødum, Jenny L. Persson
Publié dans: International Journal of Cancer, Numéro 146/6, 2019, Page(s) 1686-1699, ISSN 0020-7136
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/ijc.32607

Different isolation approaches lead to diverse glycosylated extracellular vesicle populations

Auteurs: Daniela Freitas, Meritxell Balmaña, Juliana Poças, Diana Campos, Hugo Osório, Andriana Konstantinidi, Sergey Y. Vakhrushev, Ana Magalhães, Celso A. Reis
Publié dans: Journal of Extracellular Vesicles, Numéro 8/1, 2019, Page(s) 1621131, ISSN 2001-3078
Éditeur: Taylor & Francis
DOI: 10.1080/20013078.2019.1621131

Synthesis of an Alkyne-Modified Bleomycin Disaccharide Precursor, Conversion to a 18 F-Labeled Radiotracer, and Preliminary in vivo-PET Imaging Studies

Auteurs: Sajal K. Maity, Cheng-Bin Yim, Satish Jadhav, Alejandra Verhassel, Johanna Tuomela, Olof Solin, Tove J. Grönroos, Pasi Virta
Publié dans: European Journal of Organic Chemistry, Numéro 2019/1, 2019, Page(s) 156-163, ISSN 1434-193X
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.201801488

Glycosylation in cancer and infection – the role of sialic acid

Auteurs: Yuecheng Zhang
Publié dans: 2021
Éditeur: Malmö University

Digital holographic cytometry - Macrophage uptake of nanoprobes

Auteurs: Louise Sternbæk, Martha Wamaitha Kimani, Kornelia Gawlitza Birgit Janicke, Kersti Alm, and Anette Gjörloff Wingren
Publié dans: Imaging&Microscopy, Numéro 1, 2019, Page(s) 21-23
Éditeur: Wiley

Dual-Fluorescent Nanoparticle Probes Consisting of a Carbon Nanodot Core and a Molecularly Imprinted Polymer Shell

Auteurs: Shan Jiang, Kornelia Gawlitza, Knut Rurack
Publié dans: Molecularly Imprinted Polymers - Methods and Protocols, Numéro 2359, 2021, Page(s) 195-208, ISBN 978-1-0716-1628-4
Éditeur: Springer US
DOI: 10.1007/978-1-0716-1629-1_17

Droits de propriété intellectuelle

FLUORESCENT PARTICLES WITH MOLECULARLY IMPRINTED FLUORESCENT POLYMER SHELLS FOR CELL STAINING APPLICATIONS IN CYTOMETRY AND MICROSCOPY

Numéro de demande/publication: 20 19066550
Date: 2019-06-21
Demandeur(s): BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG

FLUORESCENT PARTICLES WITH MOLECULARLY IMPRINTED FLUORESCENT POLYMER SHELLS FOR CELL STAINING APPLICATIONS IN CYTOMETRY AND MICROSCOPY

Numéro de demande/publication: 20 19066550
Date: 2019-06-21
Demandeur(s): PHASE HOLOGRAPHIC IMAGING PHI AB

FLUORESCENT PARTICLES WITH MOLECULARLY IMPRINTED FLUORESCENT POLYMER SHELLS FOR CELL STAINING APPLICATIONS IN CYTOMETRY AND MICROSCOPY

Numéro de demande/publication: 20 19066550
Date: 2019-06-21
Demandeur(s): MALMO UNIVERSITET

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