Multidisciplinary European training network for development of personalized anti-infective medical devices combining printing technologies and antimicrobial functionality

Livrables

A manual of standardized methods and minimum information guidelines for biofilm experiments

A manual containing the standardized methods and minimum information guidelines, for anti-biofilm efficacy endpoint methodologies relevant to the project.

Publications

PRINT-AID publications.

PRINT-AID website and social media

Preparation of PRINT-AID website and social media outlets.

PRINT-AID online courses

Completed online courses for ESRs in PRINT-AID (and other students).

Methodological pipeline

A methodological pipeline/platform of methods and tools specifically optimized for chemical screens.

ESR recruitment course for ESR selection

Recruitment course for ESR organized in Porto. Co-lead beneficiary: UPORTO.

PRINT-AID Outreach Conference

Outreach conference organized.

ESRs local school visits

Visits to local schools by the ESRs to disseminate the project.

Publications

Production and Characterization of Catheters Capable of Resisting Device Associated Infection

Auteurs: Bahaa Shaqour, Clara Guarch Pérez, Augusto Vazquez-Rodriguez, Juliana Aizawa, Emilia Choińska, Martijn Riool, Bart Verleije, Koen Beyers, Livia Ferrari, Antonio Felici, Sebastian A. J. Zaat, Wojciech Święszkowski, Paul Cos
Publié dans: Abstract, Oral Presentation/Print-Aid Outreach Conference, 2020
Éditeur: Print-Aid

Is gelatin metacrylate the future 3D printing antimicrobial coating?

Auteurs: CM Guarch Pérez, D Martínez-Pérez, W Swieszkowski, M Riool, SAJ Zaat
Publié dans: Abstract, Oral Presentation/eCM XIX: Orthopaedic Infection, Davos, Switzerland, 2019, Page(s) 18
Éditeur: eCM

Drop on demand antimicrobial coatings to combat biomaterial-associated infections

Auteurs: D. Martínez Pérez, C. Guarch Pérez, I. Reigada, A. Fallarero, E. Choińska, M. Riool, S.A.J. Zaat, W. Święszkowski
Publié dans: Abstract, Oral Presentation/Print-Aid Outreach Conference, 2020
Éditeur: Print-Aid

Evaluating biofilm experimental methods

Auteurs: J. Allkja, A.E. Parker, NF. Azevedo, DM. Goeres
Publié dans: Abstract, Oral Presentation/Print-Aid Outreach Conference, 2020
Éditeur: Print-Aid

Production of ciprofloxacin loaded tubes as positive control for evaluating Ventilator Associated Pneumonia prevention in a mouse model

Auteurs: Juliana Aizawa, Bahaa Shaqour, Clara Guarch-Pérez, Emilia Choińska, Martijn Riool, Bart Verleije, Koen Beyers, Sebastian A. J. Zaat, Wojciech Święszkowski, Paul Cos
Publié dans: Abstract, Oral Presentation/Print-Aid Outreach Conference, 2020
Éditeur: Print-Aid

Local delivery of the antimicrobial peptide SAAP-148 from a 3D-printed degradable PLGA coating to prevent orthopaedic infections

Auteurs: C.M. Guarch Pérez, D. Martínez Pérez, M. Riool, W. Święszkowski, S.A.J. Zaat
Publié dans: Abstract, Oral Presentation/Print-Aid Outreach Conference, 2020
Éditeur: Print-Aid

Applying drug repurposing to produce novel medical devices with antibacterial properties: In vitro and In vivo proof of concept

Auteurs: Augusto Vazquez, Bahaa Shaqour, Bart Verleije, Koen Beyers, David Martinez, Wojciech Święszkowski, Clara Guarch Pérez, Sebastian Zaat, Livia Ferrari, Antonio Felici
Publié dans: Abstract, Oral Presentation/Print-Aid Outreach Conference, 2020
Éditeur: Print-Aid

Optimization of a high-throughput screening platform in 384-well plates for exploration of anti-biofilm activity

Auteurs: Shella Gilbert-Girard, Malena Skogman, Kirsi Savijoki, Jari Yli-Kauhaluoma and Adyary Fallarero
Publié dans: Abstracts, poster, Biofilms 8 Conference, 2018
Éditeur: Biofilms 8 Conference

Effects of African marigold (Tagete erecta) on Staphylococcus aureus (ATCC25923), Staphylococcus aureus Newman and Staphylococcus epidermis (ATCC RP62A) biofilms

Auteurs: Cristina Moliner; Inés Reigada; Carlota Gómez-Rincón; Malena Skogman; Adyary Fallarero
Publié dans: Abstract, poster, Biofilms 8 Conference, 2018
Éditeur: Biofilms 8

Antimicrobial evaluation of a 3D-printed dual antibiotic-loaded PLGA microparticles-GelMa hydrogel

Auteurs: Clara Mar Guarch Pérez, David Martínez Pérez, Martijn Riool, Wojciech Święszkowski, Sebastian Zaat
Publié dans: Abstract, Poster/Nederlandse Vereniging voor Medische Microbiologie (NVMM), 2019
Éditeur: Nederlandse Vereniging voor Medische Microbiologie (NVMM)

Principles of method standardization

Auteurs: Allkja, J., Parker, A.E., Azevedo, N.F., Goeres, D.M.
Publié dans: Abstract, Oral Presentation/eCM XIX: Orthopaedic Infection, Davos, Switzerland, 2019, 2019, Page(s) 17
Éditeur: Orthopaedic Infection, Davos, Switzerland

Characterization of the activity of three natural products as potential antimicrobials against Staphylococcus aureus

Auteurs: Shella Gilbert-Girard, Kirsi Savijoki, Jari Yli-Kauhaluoma, Adyary Fallarero
Publié dans: Abstract, Poster/Nordic Natural Products Conference, Flúðir, Iceland, 2019, 2019
Éditeur: Nordic Natural Products Conference

Biofilm inhibiting effects of two Dehydroabietic acid derivatives on clinically relevant surfaces in the presence of host cells

Auteurs: I. Reigada; K. Savijoki; J. Yli Kauhaluoma; A. Fallarero
Publié dans: Abstract, Poster/Nordic Natural Product Conference (NNPC), Flúðir, Iceland, 2019, 2019
Éditeur: Nordic Natural Product Conference (NNPC)

Strategies to prevent biomaterials from Staphylococcus aureus infections effect of dehydroabietic acic derivatives on biomaterials pre-incubated with human cells

Auteurs: I. Reigada; K. Savijoki; J. Yli Kauhaluoma; A. Fallarero
Publié dans: Abstract, Oral Presentation/eCM XIX: Orthopaedic Infection, Davos, Switzerland 2019, 2019, Page(s) 16
Éditeur: eCM XIX: Orthopaedic Infection, Davos, Switzerland

A simplified process for producing test samples for VAP model using Additive Manufacturing

Auteurs: B. Shaqour, J. Aizawa, E. Choińska, Z. Górecka, B. Verleije, K. Beyers, W. Święszkowski, P. Cos
Publié dans: Abstract, Poster/In: 30th Annual Conference of the European Society for Biomaterials. Dresden, Germany. Sept. 9-13, 2019, 2019
Éditeur: European Society for Biomaterials

Comparison between physical and solvent mixing in FFF 3D printed drug loaded devices

Auteurs: B. Shaqour, E. Choińska, Ż. Górecka, B. Verleije, K. Beyers, W. Święszkowski, P. Cos
Publié dans: Abstract, Poster/2019 eCM XIX: Orthopaedic Infection, Davos, Switzerland. June 26-28, 2019, 2019, Page(s) P28
Éditeur: eCM XIX: Orthopaedic Infection

The effect of fosmidomycin prodrugs against Acinetobacter baumannii biofilms

Auteurs: Frits van Charante, Charlotte Courtens, Serge van Calenbergh, Tom Coenye
Publié dans: Abstract, Poster/BSM (Belgian Society for Microbiology) conference 2019 (Brussels, Belgium), 2019
Éditeur: Belgian Society for Microbiology

Why we need minimum information guidelines

Auteurs: Jontana Allkja
Publié dans: Invited oral presentation/Eurobiofilms 2019, 2019
Éditeur: Eurobiofilms

The use of fosmidomycin prodrugs against Acinetobacter baumannii in 3D-printed wound dressing

Auteurs: Frits van Charante, David Martinez Perez, Charlotte Courtens, Wojciech Swieszkowski, Serge Van Calenbergh, Tom Coenye
Publié dans: Abstract, Oral Presentation/Print-Aid Outreach Conference, 2020
Éditeur: Print-Aid

Identification and characterization of fingolimod as a repurposed antibacterial compound

Auteurs: S. Gilbert-Girard, K. Savijoki, J. Yli-Kauhaluoma, A. Fallarero
Publié dans: Abstract, Oral Presentation/Print-Aid Outreach Conference, 2020
Éditeur: Print-Aid

3D printed hybrid antimicrobial coating for prevention of implant-associated osteomyelitis

Auteurs: D. Martínez Pérez, C. Guarch Pérez, I. Reigada, A. Fallarero, E. Choińska, S.A.J. Zaat, W. Święszkowski
Publié dans: Abstract, Oral Presentation/eCM XIX: Orthopaedic Infection, Davos, Switzerland 2019, 2019, Page(s) 19
Éditeur: eCM Online Periodical

Effect of a dehydroabietic acic derivative on the prevention of biofilm formation in biomaterials pre-conditioned serum proteins in a co-culture system including SaOS-2 cells and clinical and collection strains of Staphylococcus aureus

Auteurs: I. REIGADA, R. PÉREZ-TANOIRA, J.Z. PATEL, K. SAVIJOKI, J. YLI-KAUHALUOMA , T. J. KINNARI AND A. FALLARERO
Publié dans: Abstract, Oral Presentation/Print-Aid Outreach Conference, 2020
Éditeur: Print-Aid

Screening of FDA-Approved Drugs Using a 384-Well Plate-Based Biofilm Platform: The Case of Fingolimod

Auteurs: Shella Gilbert-Girard, Kirsi Savijoki, Jari Yli-Kauhaluoma, Adyary Fallarero
Publié dans: Microorganisms, Numéro 8/11, 2020, Page(s) 1834, ISSN 2076-2607
Éditeur: MDPI, Microorganisms
DOI: 10.3390/microorganisms8111834

Non-leaching, Highly Biocompatible Nanocellulose Surfaces That Efficiently Resist Fouling by Bacteria in an Artificial Dermis Model

Auteurs: Ghada Hassan, Nina Forsman, Xing Wan, Leena Keurulainen, Luis M. Bimbo, Susanne Stehl, Frits van Charante, Michael Chrubasik, Aruna S. Prakash, Leena-Sisko Johansson, Declan C. Mullen, Blair F. Johnston, Ralf Zimmermann, Carsten Werner, Jari Yli-Kauhaluoma, Tom Coenye, Per E. J. Saris, Monika Österberg, Vânia M. Moreira
Publié dans: ACS Applied Bio Materials, Numéro 3/7, 2020, Page(s) 4095-4108, ISSN 2576-6422
Éditeur: ACS
DOI: 10.1021/acsabm.0c00203

3D-Printed Drug Delivery Systems: The Effects of Drug Incorporation Methods on Their Release and Antibacterial Efficiency

Auteurs: Bahaa Shaqour, Inés Reigada, Żaneta Górecka, Emilia Choińska, Bart Verleije, Koen Beyers, Wojciech Święszkowski, Adyary Fallarero, Paul Cos
Publié dans: Materials, Numéro 13/15, 2020, Page(s) 3364, ISSN 1996-1944
Éditeur: MDPI Open Access Publishing
DOI: 10.3390/MA13153364

Strategies to Prevent Biofilm Infections on Biomaterials: Effect of Novel Naturally-Derived Biofilm Inhibitors on a Competitive Colonization Model of Titanium by Staphylococcus aureus and SaOS-2 Cells

Auteurs: Inés Reigada, Ramón Pérez-Tanoira, Jayendra Z. Patel, Kirsi Savijoki, Jari Yli-Kauhaluoma, Teemu J. Kinnari, Adyary Fallarero
Publié dans: Microorganisms, Numéro 8/3, 2020, Page(s) 345, ISSN 2076-2607
Éditeur: MDPI
DOI: 10.3390/microorganisms8030345

Minimum information guideline for spectrophotometric and fluorometric methods to assess biofilm formation in microplates

Auteurs: Jontana Allkja, Thomas Bjarnsholt, Tom Coenye, Paul Cos, Adyary Fallarero, Joe J. Harrison, Susana P. Lopes, Antonio Oliver, Maria Olivia Pereira, Gordon Ramage, Mark E. Shirtliff, Paul Stoodley, Jeremy S. Webb, Sebastian A.J. Zaat, Darla M. Goeres, Nuno Filipe Azevedo
Publié dans: Biofilm, Numéro 2, 2020, Page(s) 100010, ISSN 2590-2075
Éditeur: Elsvier
DOI: 10.1016/j.bioflm.2019.100010

Optimization of a High-Throughput 384-Well Plate-Based Screening Platform with Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 15442 Biofilms

Auteurs: Shella Gilbert-Girard, Kirsi Savijoki, Jari Yli-Kauhaluoma, Adyary Fallarero
Publié dans: International Journal of Molecular Sciences, Numéro 21/9, 2020, Page(s) 3034, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21093034

Production of Drug Delivery Systems Using Fused Filament Fabrication: A Systematic Review

Auteurs: Bahaa Shaqour, Aseel Samaro, Bart Verleije, Koen Beyers, Chris Vervaet and Paul Cos
Publié dans: Pharmaceutics, 2020, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12060517

Combined Effect of Naturally-Derived Biofilm Inhibitors and Differentiated HL-60 Cells in the Prevention of Staphylococcus aureus Biofilm Formation

Auteurs: Inés Reigada, Clara Guarch-Pérez, Jayendra Z. Patel, Martijn Riool, Kirsi Savijoki, Jari Yli-Kauhaluoma, Sebastian A. J. Zaat, Adyary Fallarero
Publié dans: Microorganisms, Numéro 8/11, 2020, Page(s) 1757, ISSN 2076-2607
Éditeur: MDPI, Microorganisms
DOI: 10.3390/microorganisms8111757

Orthogonal Approaches for Studying Bacterial Biofilms using Photometric Detection with Thermo Scientific Multiskan Sky and Brightfield Imaging with EVOS FL Auto Imaging System

Auteurs: Inés Reigada, Ilkka Miettinen, Kirsi Savijoki, Adyary Fallarero
Publié dans: Application note, Thermo Fisher Scientific, 2018
Éditeur: Thermo Fisher Scientific

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