Mechanical Chirality: Synthesis, Properties and Applications at a New Horizon in Supramolecular Stereochemistry

Project Information

MechaniChiral

Grant agreement ID: 724987

DOI 10.3030/724987

Project closed

EC signature date 21 March 2017

Start date 1 April 2017

End date 30 September 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 998 927,50

EU contribution € 1 998 927,50

Coordinated by

UNIVERSITY OF SOUTHAMPTON
United Kingdom

Publications

Peer reviewed articles (24)

Using the Mechanical Bond to Tune the Performance of a Thermally Activated Delayed Fluorescence Emitter

Author(s): Pachaiyappan Rajamalli; Pachaiyappan Rajamalli; Federica Rizzi; Wenbo Li; Michael A. Jinks; Abhishek Gupta; Beth Laidlaw; Ifor D. W. Samuel; Thomas J. Penfold; Stephen M. Goldup; Eli Zysman-Colman
Published in: Angewandte Chemie (International Ed. in English), Issue 7, 2021, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ange.202101870

Mechanically axially chiral catenanes and noncanonical mechanically axially chiral rotaxanes

Author(s): John R.J. Maynard, Peter Gallagher, David Lozano, Patrick Butler, and Stephen M. Goldup
Published in: Nature Chemistry, 2022, Page(s) 1038–1044, ISSN 1755-4330
Publisher: Nature Publishing Group
DOI: 10.1038/s41557-022-00973-6

A chiral interlocking auxiliary strategy for the synthesis of mechanically planar chiral rotaxanes

Author(s): Alberto de Juan; David Lozano; Andrew W. Heard; Michael A. Jinks; Jorge Meijide Suarez; Graham J. Tizzard; Stephen M. Goldup
Published in: Nature Chemistry, Issue 1, 2022, ISSN 1755-4330
Publisher: Nature Publishing Group
DOI: 10.1038/s41557-021-00825-9

Vibrational circular dichroism spectroscopy for probing the expression of chirality in mechanically planar chiral rotaxanes.

Author(s): Mark A. J. Koenis; C. S. Chibueze; Michael A. Jinks; Valentin P. Nicu; Lucas Visscher; Stephen M. Goldup; Wybren Jan Buma; Wybren Jan Buma
Published in: Chemical Science, Issue 4, 2020, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sc02485f

Spin-labelled mechanically interlocked molecules as models for the interpretation of biradical EPR spectra

Author(s): Lorenzo Gualandi; Paola Franchi; Elisabetta Mezzina; Stephen M. Goldup; Marco Lucarini
Published in: Chemical Science, Issue 3, 2021, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.26434/chemrxiv.14247224.v1

Rotaxane CoII Complexes as Field-Induced Single-Ion Magnets

Author(s): Martina Cirulli; Enrico Salvadori; Zhihui Zhang; Michael Dommett; Floriana Tuna; Heiko Bamberger; James E. M. Lewis; James E. M. Lewis; Amanpreet Kaur; Graham J. Tizzard; Joris van Slageren; Rachel Crespo-Otero; Stephen M. Goldup; Maxie M. Roessler
Published in: Angewandte Chemie International Edition, Issue 4, 2021, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202103596

A co-conformationally “topologically” chiral catenane

Author(s): Arnau Rodríguez-Rubio; Andrea Savoini; Florian Modicom; Patrick Butler; Stephen M. Goldup
Published in: Journal of the American Chemical Society, 2022, Page(s) 11927–11932, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c02029

Anion-π Catalysis Enabled by the Mechanical Bond

Author(s): John R. J. Maynard; Bartomeu Galmés; Athanasios D. Stergiou; Mark D. Symes; Antonio Frontera; Steve Goldup
Published in: Angewandte Chemie International Edition, Issue 2, 2022, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.26434/chemrxiv-2021-r591n

Chelating Rotaxane Ligands as Fluorescent Sensors for Metal Ions

Author(s): Mathieu Denis, Jessica Pancholi, Kajally Jobe, Michael Watkinson, Stephen M. Goldup
Published in: Angewandte Chemie International Edition, Issue 57/19, 2018, Page(s) 5310-5314, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201712931

Porphyrinoid rotaxanes: building a mechanical picket fence

Author(s): T. H. Ngo, J. Labuta, G. N. Lim, W. A. Webre, F. D'Souza, P. A. Karr, J. E. M. Lewis, J. P. Hill, K. Ariga, S. M. Goldup
Published in: Chemical Science, Issue 8/9, 2017, Page(s) 6679-6685, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c7sc03165c

Chirality in rotaxanes and catenanes

Author(s): E. M. G. Jamieson, F. Modicom, S. M. Goldup
Published in: Chemical Society Reviews, Issue 47/14, 2018, Page(s) 5266-5311, ISSN 0306-0012
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8cs00097b

A Fluorescent Ditopic Rotaxane Ion-Pair Host

Author(s): Mathieu Denis, Lei Qin, Peter Turner, Katrina A. Jolliffe, Stephen M. Goldup
Published in: Angewandte Chemie International Edition, Issue 57/19, 2018, Page(s) 5315-5319, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201713105

Efficient Multicomponent Active Template Synthesis of Catenanes

Author(s): James E. M. Lewis, Florian Modicom, Stephen M. Goldup
Published in: Journal of the American Chemical Society, Issue 140/14, 2018, Page(s) 4787-4791, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.8b01602

Stereoselective Synthesis of Mechanically Planar Chiral Rotaxanes

Author(s): Michael A. Jinks, Alberto de Juan, Mathieu Denis, Catherine J. Fletcher, Marzia Galli, Ellen M. G. Jamieson, Florian Modicom, Zhihui Zhang, Stephen M. Goldup
Published in: Angewandte Chemie International Edition, Issue 57/45, 2018, Page(s) 14806-14810, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201808990

Chelating Rotaxane Ligands as Fluorescent Sensors for Metal Ions

Author(s): Mathieu Denis, Jessica Pancholi, Kajally Jobe, Michael Watkinson, Stephen M. Goldup
Published in: Angewandte Chemie, Issue 130/19, 2018, Page(s) 5408-5412, ISSN 0044-8249
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ange.201712931

Synthesis and Characterisation of a Paramagnetic [2]Rotaxane Based on a Crown Ether-Like Wheel Incorporating a Nitroxide Motif

Author(s): Valentina Bleve, Paola Franchi, Evangelia Konstanteli, Lorenzo Gualandi, Stephen M. Goldup, Elisabetta Mezzina, Marco Lucarini
Published in: Chemistry - A European Journal, Issue 24/5, 2018, Page(s) 1198-1203, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201704969

An Auxiliary Approach for the Stereoselective Synthesis of Topologically Chiral Catenanes

Author(s): Mathieu Denis, James E.M. Lewis, Florian Modicom, Stephen M. Goldup
Published in: Chem, Issue 5/6, 2019, Page(s) 1512-1520, ISSN 2451-9294
Publisher: Elsevier
DOI: 10.1016/j.chempr.2019.03.008

Rotaxane-Based Transition Metal Complexes: Effect of the Mechanical Bond on Structure and Electronic Properties

Author(s): Martina Cirulli, Amanpreet Kaur, James E. M. Lewis, Zhihui Zhang, Jonathan A. Kitchen, Stephen M. Goldup, Maxie M. Roessler
Published in: Journal of the American Chemical Society, Issue 141/2, 2019, Page(s) 879-889, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.8b09715

Chemical Consequences of the Mechanical Bond: A Tandem Active Template-Rearrangement Reaction

Author(s): Florian Modicom, Ellen M. G. Jamieson, Elise Rochette, Stephen M. Goldup
Published in: Angewandte Chemie International Edition, Issue 58/12, 2019, Page(s) 3875-3879, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201813950

Synthesis of a Mechanically Planar Chiral Rotaxane Ligand for Enantioselective Catalysis

Author(s): Andrew W. Heard, Stephen M. Goldup
Published in: Chem, Issue 6/4, 2020, Page(s) 994-1006, ISSN 2451-9294
Publisher: Elsevier
DOI: 10.1016/j.chempr.2020.02.006

Simplicity in the Design, Operation, and Applications of Mechanically Interlocked Molecular Machines

Author(s): Andrew W. Heard, Stephen M. Goldup
Published in: ACS Central Science, Issue 6/2, 2020, Page(s) 117-128, ISSN 2374-7943
Publisher: American Chemical Society
DOI: 10.1021/acscentsci.9b01185

AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides

Author(s): Amanda Acevedo-Jake, Andrew T. Ball, Marzia Galli, Mikiembo Kukwikila, Mathieu Denis, Daniel G. Singleton, Ali Tavassoli, Stephen M. Goldup
Published in: Journal of the American Chemical Society, Issue 142/13, 2020, Page(s) 5985-5990, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c01670

Rotaxane Pt II -complexes: mechanical bonding for chemically robust luminophores and stimuli responsive behaviour

Author(s): Zhihui Zhang, Graham J. Tizzard, J. A. Gareth Williams, Stephen M. Goldup
Published in: Chemical Science, Issue 11/7, 2020, Page(s) 1839-1847, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9sc05507j

Metal ions in the synthesis of interlocked molecules and materials

Author(s): Lewis, James E. M.; Beer, Paul D.; Loeb, Stephen J.; Goldup, Stephen M.
Published in: Chemical Society Reviews, Issue 2, 2017, ISSN 0306-0012
Publisher: Royal Society of Chemistry
DOI: 10.1039/c7cs00199a

Non-peer reviewed articles (2)

A [3]Rotaxane Host Selects Between Stereoisomers

Author(s): Mathieu Denis, Stephen Michael Goldup
Published in: Angewandte Chemie International Edition, Issue 57/17, 2018, Page(s) 4462-4464, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201800665

Chirality makes a move

Author(s): Ellen M. G. Jamieson, Stephen M. Goldup
Published in: Nature Chemistry, Issue 11/9, 2019, Page(s) 765-767, ISSN 1755-4330
Publisher: Nature Publishing Group
DOI: 10.1038/s41557-019-0320-z