Project description DEENESFRITPL 3D games for better treatment of children’s lazy eye Paediatric amblyopia (PA, lazy eye) is a common, developmental vision disorder in children. Typical treatment for PA is based on forcing the use of the bad eye to obtain a clear retinal image in each eye. But several aspects of PA vision disorder, like the involvement of 3D vision and motor function, are still understudied and not integrated in the rehabilitation process. The EU-funded V-HAB project will conduct a deep investigation into vision-related sciences with emphasis on the role of motor control as well as selective attention in PA. This project will improve the efficiency of PA therapy and introduce innovative engaging 3D games in a virtual environment to make the therapy attractive for children. Show the project objective Hide the project objective Objective To reach for a bottle (motor), we need to be able to identify its properties (attention) and know where in space it is located (3-dimensional (3D) vision). This cascade is however impaired in some developmental disorders of vision, like Paediatric Amblyopia (PA) or lazy eye. With this proposal, I first aim to gain insights in the underlying deficits of PA, by combining expertise from the vision sciences, cognition and motor control research fields. These insights will provide a deeper understanding of the core deficits of children with PA, and their inter-relationship. I will put specific emphasis on the study of 3D vision and its impact on selective attention and motor planning, as these have previously been understudied, despite their clear impact on vision and potential coexistence in PA. Second, I aim to test the efficiency of a novel, ethological, and engaging 3D games in a virtual reality environment to improve vision in children with PA. Thirdly, I will examine whether the improvements on vision are accompanied by changes in attention and motor control and which are the underlying brain mechanisms of such improvements. Lastly, by using artificial intelligence approaches on treatment outcome, I will be able to provide guidelines toward a personalized medicine tailored to the patient’s needs. To succeed in this project, I will (i) combine measures of the traditional basic vision tests with novel functional vision evaluation, (ii) quantify uni- and multisensory selective attention with behavioural and brain imaging (electrical neuroimaging) methods, (iii) integrate sensor-based measures of motor planning during reaching, (iv) develop a novel, efficient and ethological virtual reality training to recover 3D vision in children with PA. This project will accumulate clinically relevant results that will be disseminated to the scientific community and communicated to the clinicians and the children’s families through a variety of activities. Fields of science natural sciencescomputer and information sciencesartificial intelligencemedical and health scienceshealth sciencespersonalized medicinemedical and health sciencesclinical medicinepaediatricsnatural sciencescomputer and information sciencessoftwaresoftware applicationsvirtual reality Keywords Rehabilitation Virtual reality Motor control Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2019 - Individual Fellowships Call for proposal H2020-MSCA-IF-2019 See other projects for this call Funding Scheme MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF) Coordinator HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE Net EU contribution € 203 149,44 Address Route de Moutier 14 2800 Delemont Switzerland See on map Region Schweiz/Suisse/Svizzera Espace Mittelland Jura Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 203 149,44
