Descripción del proyecto
Juegos en 3D para un mejor tratamiento del ojo vago en los niños
La ambliopía pediátrica (AP, ojo vago) es un trastorno común del desarrollo de la visión en niños. El tratamiento típico de la AP se basa en forzar el uso del ojo malo para obtener una imagen clara de la retina de cada ojo. Sin embargo, diversos aspectos del trastorno de la visión de la AP, como la afectación de la visión en 3D y la función motora, siguen estando escasamente estudiados y no se encuentran integrados en el proceso de rehabilitación. El proyecto financiado con fondos europeos V-HAB llevará a cabo una investigación en profundidad de las ciencias relacionadas con la visión, con un especial énfasis en el papel del control motor así como de la atención selectiva en pacientes con AP. Este proyecto aumentará la eficiencia del tratamiento de la AP e introducirá innovadores juegos 3D en un entorno virtual para conseguir que los niños se involucren con el tratamiento y lo encuentren atractivo.
Objetivo
To reach for a bottle (motor), we need to be able to identify its properties (attention) and know where in space it is located (3-dimensional (3D) vision). This cascade is however impaired in some developmental disorders of vision, like Paediatric Amblyopia (PA) or lazy eye.
With this proposal, I first aim to gain insights in the underlying deficits of PA, by combining expertise from the vision sciences, cognition and motor control research fields. These insights will provide a deeper understanding of the core deficits of children with PA, and their inter-relationship. I will put specific emphasis on the study of 3D vision and its impact on selective attention and motor planning, as these have previously been understudied, despite their clear impact on vision and potential coexistence in PA. Second, I aim to test the efficiency of a novel, ethological, and engaging 3D games in a virtual reality environment to improve vision in children with PA. Thirdly, I will examine whether the improvements on vision are accompanied by changes in attention and motor control and which are the underlying brain mechanisms of such improvements. Lastly, by using artificial intelligence approaches on treatment outcome, I will be able to provide guidelines toward a personalized medicine tailored to the patient’s needs.
To succeed in this project, I will (i) combine measures of the traditional basic vision tests with novel functional vision evaluation, (ii) quantify uni- and multisensory selective attention with behavioural and brain imaging (electrical neuroimaging) methods, (iii) integrate sensor-based measures of motor planning during reaching, (iv) develop a novel, efficient and ethological virtual reality training to recover 3D vision in children with PA. This project will accumulate clinically relevant results that will be disseminated to the scientific community and communicated to the clinicians and the children’s families through a variety of activities.
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MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)Coordinador
2800 Delemont
Suiza