Objective Improving the yield of correctly folded heterologous proteins which contain disulfide bonds by stroptomyces lividans may require the assistance of thioldisulfide oxyreductases. As a model the role of various protein disulfide isomerases in the expression and secretion of the h. Medicinalis thrombin inhibitor hirudin will be studied. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesproteins Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-3. - Key action The "Cell factory" Call for proposal Data not available Funding Scheme RGI - Research grants (individual fellowships) Coordinator JOHANN WOLFGANG GOETHE UNIVERSITAET FRANKFURT EU contribution No data Address 11,Marie-Curie-Strasse 11 60439 FRANKFURT AM-MAIN Germany See on map Total cost No data
