Objectif Improving the yield of correctly folded heterologous proteins which contain disulfide bonds by stroptomyces lividans may require the assistance of thioldisulfide oxyreductases. As a model the role of various protein disulfide isomerases in the expression and secretion of the h. Medicinalis thrombin inhibitor hirudin will be studied. Champ scientifique natural sciencesbiological sciencesbiochemistrybiomoleculesproteins Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Thème(s) 1.1.1.-3. - Key action The "Cell factory" Appel à propositions Data not available Régime de financement RGI - Research grants (individual fellowships) Coordinateur JOHANN WOLFGANG GOETHE UNIVERSITAET FRANKFURT Contribution de l’UE Aucune donnée Adresse 11,Marie-Curie-Strasse 11 60439 FRANKFURT AM-MAIN Allemagne Voir sur la carte Coût total Aucune donnée