Objective The design and construction of binuclear copper centre based biosensors and biocatalysts are the two objectives of this project. Toward these aims we propose to investigate the molecular basis of reversible oxygen binding and activation as observed in the active site of structurally homologous binuclear copper proteins that physiologically function either as oxygen carrier or as selective monooxygenases and catechu oxidises. The objectives will be achieved by inclusion of these proteins into optically and chemically inert solid matrices. This will allow our industrial partners to construct a low cost optical oxygen biosensor for biomedical use and will provide a selective, removable biocatalyst for the conversion of endogenous phenol substrates in food processing. The available genetically engineered systems will allow for the tailoring of sensitivity and specificity of the proteins used to the implementation demands. Fields of science engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensorsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesbiological sciencesecologyecosystemsnatural scienceschemical sciencescatalysisbiocatalysis Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-5. - Key action Sustainable Agriculture, Fisheries and Forestry Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator CAB INTERNATIONAL EU contribution No data Address Bakeham Lane TW20 9TY EGHAM,SURREY United Kingdom See on map Total cost No data Participants (5) Sort alphabetically Sort by EU Contribution Expand all Collapse all ARAGONESAS AGRO SA Spain EU contribution No data Address Paseo de Recoletos 27, 4a 28004 MADRID See on map Total cost No data IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE United Kingdom EU contribution No data Address Silwood Park SL5 7PY ASCOT See on map Total cost No data SOMYCEL S.A. France EU contribution No data Address Z.I. Sud, Route de Tours 37130 LANGEAIS See on map Total cost No data UNIVERSIDAD DE CORDOBA Spain EU contribution No data Address Avenida Menéndez Pidal s/n 14071 CORDOBA See on map Total cost No data UNIVERSITA DEGLI STUDI DI BARI Italy EU contribution No data Address Via Amendola 165/A 70126 BARI See on map Total cost No data