Objective Molecular Biophysics has reached the point where it can move from model system studies to a direct intracellular approach of molecular events in single livingcells.Five Laboratories of Molecular Biophysics belonging to three European Countries propose to bring together their know how in optical microspectrometries and cellular biology in order to develop this new approach at the single cell level, to push back its limits and to demonstrate on some examples its advantages over more classical biophysical or biochemical approaches.They will concentrate their efforts on the investigation of the mechanisms of action of two families of drugs used in chemotherapy and of the mechanisms of cell-cell interaction in cytotoxicity.A part of their efforts will be devoted to the introduction of new physical parameters in the analysis(time resolution, extension of the excitation wavelength range)in order to fully exploit the possibilities offered by these spectroscopies. Fields of science natural sciencesbiological sciencesbiophysicsnatural sciencesphysical sciencesopticsspectroscopy Programme(s) FP2-SCIENCE - Programme plan (EEC) to stimulate the international cooperation and interchange needed by European research scientists (SCIENCE), 1988-1992 Topic(s) Data not available Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator Institut Curie EU contribution No data Address 11 rue Pierre et Marie Curie 75231 Paris France See on map Total cost No data Participants (3) Sort alphabetically Sort by EU Contribution Expand all Collapse all Fondazione Internazionale Biotecnologie Italy EU contribution No data Address Via Hachej 10 20129 Milano See on map Total cost No data University of Twente Netherlands EU contribution No data Address 5,Drienerlolaan 5 7500 AE ENSCHEDE See on map Links Website Opens in new window Total cost No data Université de Reims Champagne - Ardenne France EU contribution No data Address 23 rue Boulard 51100 Reims See on map Total cost No data
