Objetivo Through ERC-funded research, Prof. Wuite developed the DN-X-PRO as a method and instrument that enables direct visualization of DNA-protein interactions in real-time, at the single-molecule level, at super-resolution, under conditions similar to the cellular environment. Using the DN-X-PRO, researchers can manipulate and measure mechanical and structural properties of DNA-protein complexes, while simultaneously localizing individual proteins on the DNA, with nanometer accuracy and super-resolution. To date, such studies can only be performed by separate application of two or three different instruments, in conditions that do not resemble the cellular environment, with lower resolution. This results in a strong proposition to biomolecular researcher labs worldwide, allowing conduct of a range of experiments that are very complicated or not possible to date.The PREMADIX project will result in a clear valorization strategy — based on elemental business insights that permit estimation of commercial and financial feasibility and business modeling and planning. Besides, a sound intellectual property (IP) strategy will be defined. In parallel, the DN-X-PRO will be physically prepared for marketing, translating the current prototype into a robust and user-friendly design accompanied by product sheets, control and analysis software, and user manuals. Finally, the PREMADIX team will assemble a business team, and start discussions with potential strategic partners and financers. By doing so, at the end of PREMADIX, the team will have strong assets for market introduction. Ámbito científico natural sciencescomputer and information sciencessoftwarenatural sciencesbiological sciencesgeneticsDNAnatural sciencesphysical sciencesopticsmicroscopysuper resolution microscopynatural sciencesbiological sciencesbiochemistrybiomoleculesproteins Programa(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) ERC-OA-2013-PoC - European Research Council ERC Proof of Concept Convocatoria de propuestas ERC-2013-PoC Consulte otros proyectos de esta convocatoria Régimen de financiación CSA-SA(POC) - Supporting action (Proof of Concept) Institución de acogida STICHTING VU Aportación de la UE € 150 000,00 Dirección DE BOELELAAN 1105 1081 HV Amsterdam Países Bajos Ver en el mapa Región West-Nederland Noord-Holland Groot-Amsterdam Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Yvonne Kops (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Beneficiarios (1) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo STICHTING VU Países Bajos Aportación de la UE € 150 000,00 Dirección DE BOELELAAN 1105 1081 HV Amsterdam Ver en el mapa Región West-Nederland Noord-Holland Groot-Amsterdam Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Yvonne Kops (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos
