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FP7-nEUROPt project. Final Results: International Workshop in Milan, Italy

Neuroimaging techniques have vastly influenced the understanding of diseases such as stroke, multiple sclerosis and epilepsy.
In this context the European Commission, through its Seventh Framework Programme, has chartered the Non-invasive imaging of brain function and disease by pulsed near infrared light (nEUROPt) project (2008-2012).

12 March 2012 - 13 March 2012
Germany
In order to present the results achieved during the whole project period, the nEUROPt partners will organize an International Workshop.

This Workshop will be held on March 12th-13th, 2012 in the city of Milan, and will see the participation of all project partners and of invited European and International speakers from the biomedical, photonic and neurological field.

Program
Monday March 12

8:30-9:00 Opening: R. Cubeddu, Coordinator
CFc: C. Finocchiaro

9:00 – 10:15 WP1 Novel strategies for time-domain diffuse optical imaging of the
brain

Invited: T. Durduran (ICFO, Barcelona, Spain)
"Bed-side neuro-monitoring with hybrid diffuse optics with examples of different clinical questions that could be tackled"

Time-resolved diffuse optical imaging and spectroscopy at short source-detector distances
PoliMi_FIS: A. Pifferi, D. Contini, A. Dalla Mora, L. Spinelli, A. Torricelli,
R. Cubeddu
PTB: M. Mazurenka, A. Jelzow, H. Wabnitz, R. Macdonald
UniFi: F. Martelli, G. Zaccanti
MPD: A. Tosi, G. Boso, F. Zappa
FIANIUM: J. Clowes

Non-contact scanning system for time-domain brain imaging
PTB: M. Mazurenka, A. Jelzow, H. Wabnitz, R. Macdonald
PoliMi_FIS: D. Contini, L. Spinelli, A. Pifferi, R. Cubeddu, A. Dalla Mora
MPD: A. Tosi, F. Zappa

Time-gated ICCD camera for dense brain topography
IBIB PAN: P. Sawosz, M. Kacprzak, W. Weigl, S. Wojtkiewicz, R. Maniewski,
A. Liebert
PoliMi_FIS: A. Pifferi, D. Contini, L. Spinelli, A. Torricelli, R. Cubeddu

In vivo optical spectroscopy of the head
ILM: F. Foschum, O. Fugger, M. Jäger, E. Simon, A. Kienle
PoliMi_FIS: A. Pifferi, L. Spinelli, A. Torricelli, A. Farina, I. Bargigia, R. Cubeddu
PTB: A. Jelzow, H. Wabnitz, R. Macdonald
UniFi: F. Martelli, G. Zaccanti
UCL_CS: J. Heiskala, S. Arridge
IBIB PAN: A. Liebert, P. Sawosz, D. Milej


10:15 – 11:00 WP2 Development and testing of novel photonic devices

Novel fibres and fibre-laser sources for next generation time-domain imaging
Fianium: J. Clowes
CPPM: W. Wadsworth

Single-photon detectors for optical brain imaging
MPD: A. Tosi, G. Boso, F. Zappa, A. Giudice, S. Tisa
PoliMi_FIS: A. Dalla Mora

Multidimensional TCSPC in diffuse imaging: New lasers, new detectors, new opportunities
bh: W. Becker
PTB: M. Mazurenka, H. Wabnitz
UCL: S. Magazov

11:00 – 11:30 Coffee Break

11:30 – 12:45 WP3 Modeling and computation

Invited: A. H. Gandjbakhche (NIH/NICHD, Bethesda, USA)
“Modeling Parametric Studies for   Brain Cognitive tasks using  NIRS”

Forward and inverse solvers for the nEUROPt project: UCL contribution
UCL_CS: S. Arridge, J. Heiskala, M. Schweiger

Forward and inverse solvers for the nEUROPt project: ILM contribution
ILM: A. Kienle, A. Liemert, M. Jäger, F. Foschum

 Forward and inverse solvers for the nEUROPt project: UniFi contribution
UniFi: F. Martelli, S. Del Bianco, G. Zaccanti

12:45 – 13:45 Lunch

13:45 – 15:15 WP4 Development of instrumentation for clinical applications

Invited: D. Boas (Optical Imaging Lab, Massachusetts General Hospital, Charlestown, USA)
"A second generation time domain imaging system from MGH"

A multichannel time-domain medical device for brain imaging
PoliMi_FIS: D. Contini, A. Torricelli, L. Spinelli, M. Caffini, L. Zucchelli, R. Cubeddu

A time-domain system for optical tomography of the newborn infant brain
UCL_MPB: J. C. Hebden, S. Magazov, N. Everdell, M. Varela

A time-domain brain imager for various clinical applications
PTB: O. Steinkellner, A. Jelzow, H. Wabnitz, R. Macdonald

Time-resolved instrument for simultaneous measurements of diffuse reflectance and fluorescence
IBIB PAN: M. Kacprzak, D. Milej, P. Sawosz, A. Gerega, R. Maniewski, A. Liebert

15:15 – 16:30 WP5 Standardization and quality assurance

Invited: J.P. Bouchard (INO, Quebec, Canada)
“The role of optical tissue phantoms in the development, validation and verification of medical devices”

Standardized protocols for performance assessment of time-domain brain imagers
PTB:  H. Wabnitz, R. Macdonald
PoliMi_FIS: A. Pifferi, A. Torricelli
IBIB PAN:  A. Liebert
UCL_MPB: J. Hebden
UniFi: F. Martelli, G. Zaccanti

Phantoms for the nEUROPt protocols
UniFi: P. Di Ninni, F. Martelli, D. Marcucci, G. Zaccanti

Performance assessment of clinical instruments for brain time-resolved fNIRS
PoliMi_FIS:   L. Spinelli, M. Caffini, L. Zucchelli, D. Contini, A. Pifferi, A. Torricelli,
R. Cubeddu
PTB: H. Wabnitz, A. Jelzow, M. Mazurenka, O. Steinkellner, R. Macdonald
IBIB PAN:   D. Milej, N. Zolek, M. Kacprzak, A. Liebert
UCL_MPB: S. Magazov, J. Hebden

16:30 – 17:00 Coffee Break
17:00 – 18:00 WP6 Processing and analysis of clinical data

Data integration procedures between fNIRS, fMRI and EEG signal for the
improvement of diagnostic information in CNS studies
PoliMi_BIO: S. Cerutti, A. M. Bianchi, E. Molteni, R. Sclocco, G. Baselli
PoliMi_FIS: A. Torricelli, D. Contini, M. Caffini, L. Zucchelli, L. Spinelli, R. Cubeddu
INNCB: S. Franceschetti, E. Visani, I. Gilioli, D. Rossi Sebastiano, F. Panzica

Approximation error methods in quantitative optical brain imaging
UCL_CS: S. Arridge, J. Heiskala, M. Schweiger

Analysis of in-vivo measurements based on moments of time-resolved diffuse reflectance
PTB:   A. Jelzow, O. Steinkellner, H. Wabnitz, R. Macdonald
IBIB PAN: A. Liebert, P. Sawosz, D. Milej
Charité: S. P. Koch, H. Obrig

Analysis of in-vivo measurements based on moments of time-resolved
fluorescence
IBIB PAN: D. Milej, N. Zolek, M. Kacprzak, P. Sawosz, W. Weigl, A. Gerega,
A. Liebert
PTB: A. Jelzow, O. Steinkellner, H. Wabnitz

Tuesday March 13

8:30 – 13:00 WP 7-8 Clinical tests and evaluation of novel methodologies

8:30 - 9:30
Invited: T. Austin (Rosie Maternity Hospital,Cambridge, UK)
“Shining light on the newborn brain”

Results of functional optical imaging studies on newborn infants
UCL_MPB: M. Varela, S. Magazov, J. Hebden
UCL_IWH: J. Meek

9:30 -10:30
Invited: M. Zonta (Istituto di Neuroscienze, CNR, Padua, Italy)
"The role of astrocytes in cerebral blood flow regulation"

Multimodal approach in evaluating patients with neocortical epilepsy and movement disorders
INNCB: S. Franceschetti, E. Visani, D. Rossi Sebastiano, I. Gilioli,
L. Canafoglia, A. Granvillano, E. Schiaffi, F. Panzica
PoliMi_FIS: A. Torricelli, L. Spinelli, D. Contini, M. Caffini, L. Zucchelli, R. Cubeddu
PoliMi_BIO: E. Molteni, A. M. Bianchi, G. Baselli, S. Cerutti

10:30 – 11:00 Coffee Break

11:00 – 12:00
Invited: R. N. Aslin (Dept. of Brain and Cognitive Sciences, University of Rochester, Rochester, USA)
"Specificity of hemodynamic responses from the infant cortex: Global activations or systemic artifacts?"

Non invasive optical imaging of stroke
Charité: H. Obrig, S.P. Koch, J. Steinbrink
PTB: O. Steinkellner, A. Jelzow, R. Macdonald, H. Wabnitz

12:00 – 13:00
Invited: E. Keller (University Hospital Zurich, Zurich, Switzerland)
"Assessment of cerebral oxygenation and hemodynamics in adult neurocritical care"

Application of ICG-bolus tracking method for assessment of cerebral perfusion in post-traumatic brain injury patients
MUW: W. Weigl, E. Mayzner-Zawadzka
IBIB PAN: A. Gerega, M. Kacprzak, P. Sawosz, M. Botwicz, D. Milej,
R. Maniewski,  A. Liebert

13:00 – 13:15 Concluding Remarks (R. Cubeddu, Coordinator)
Participation to the International Workshop is free of charge with compulsory registration. Maximum number of participants is 150.

Please confirm by e-mail (cf-consulting@cf-consulting.it) your attendance by 15.02.2012.
For further details see the official website of the project.
http://www.neuropt.eu/(opens in new window)
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