Proposals will aim at fostering international cooperation to develop best practices and concepts along the entire value chain for accelerating the scale-up of sustainable biofuels worldwide. Scaling up sustainable biofuels is a global challenge in terms of environmental, social, and economic sustainability, which can benefit from international collaboration and knowledge exchange. Proposals should address systemic constraints and opportunities for scaling up complete value chains of sustainable biofuels and propose solutions. Any sustainable non-food/feed biomass feedstock and any innovative technology or combinations of them should be considered. Proposals should enhance overall cost-effectiveness and sustainability of large scale production of sustainable biofuels based on Life Cycle Analysis addressing social, economic and environmental aspects. International cooperation with Mission Innovation countries is expected.