Project description DEENESFRITPL The role of the microbiome in ruminant health and production Ruminant livestock species, such as cattle, sheep and goats, depend on their body-associated microbes for critical functions and for interacting with the environment. The host ruminant-microbiome association, the holobiont, is the biological unit influencing the development, growth, health and environmental hoofprint of ruminants. The key objective of the EU-funded HoloRuminant project is to study the role of the microbiome on animal health and production efficiency. Researchers will undertake a multi-omics approach to analyse the microbiome and the host, as well as the impact of their interaction at key stages during ruminant life. The ultimate goal is to characterise and identify ruminant-associated microbiomes associated with improved production efficiency, health and welfare. Show the project objective Hide the project objective Objective Sustainability of ruminant production is of concern to society because of its implications for the environment, the economy and food security. Microbiomes associated with the host play a key role in health, welfare and environmental efficiency in ruminant production systems. However, despite the information already available, we lack the insights to precisely link the causes and mechanisms of microbial influence on ruminant phenotypes. This is because the interconnection and communication between the animal and its different microbiomes have never been studied in a deep, integrated way. The goal of the project is to elucidate the role of ruminant-associated microbiomes and their interplay with the host in early life and throughout fundamental life events. HoloRuminant will use a holistic multi-omics approach to characterise the acquisition and evolution of microbiomes from different body sites, their inheritability and their influence on the host’s resistance to disease and environmental efficiency of production. Specifically we will: determine microbiomes’ functions by combining multi-level information for microbes, host and their interaction; define microbiomes’ roles during challenging life periods such as perinatal, weaning, and after exposure to pathogens; and evaluate the effect of ruminant microbiomes on critical phenotypes for sustainable production, health and welfare. This will allow the identification of novel microbial markers for monitoring, predicting and selecting phenotypes of interest. By engaging actors from the livestock value chain, we will evaluate the socio-economic impact and acceptability of the innovations proposed among stakeholders and the public.HoloRuminant will provide highly innovative, standardized methodologies that will radically advance our understanding of the ruminant holobiont. This knowledge and the tools created will allow the use of microbiome-based diagnostics and solutions for improving ruminant sustainabilty. Keywords cattle small ruminant microbiome early life colonisation performance indicators sustainability carbon footprint microbial ecology Programme(s) H2020-EU.3.2. - SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy Main Programme H2020-EU.3.2.1.1. - Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience Topic(s) SFS-02-2020 - Healthy terrestrial livestock microbial ecosystems for sustainable production Call for proposal H2020-SFS-2018-2020 See other projects for this call Sub call H2020-SFS-2020-2 Funding Scheme RIA - Coordinator INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT Net EU contribution € 1 240 470,00 Address 147 rue de l'universite 75007 Paris France See on map Region Ile-de-France Ile-de-France Paris Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (24) Sort alphabetically Sort by Net EU contribution Expand all Collapse all AARHUS UNIVERSITET Denmark Net EU contribution € 100 035,75 Address Nordre ringgade 1 8000 Aarhus c See on map Region Danmark Midtjylland Østjylland Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 AGRESEARCH LIMITED New Zealand Net EU contribution € 0,00 Address Lincoln research centre, 1365 springs road 7674 Lincoln See on map Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 501 055,00 AGRIFOOD AND BIOSCIENCES INSTITUTE United Kingdom Net EU contribution € 179 908,75 Address Newforge lane 18a BT9 5PX Belfast See on map Region Northern Ireland Northern Ireland Belfast Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THE AGRICULTURAL RESEARCH ORGANISATION OF ISRAEL - THE VOLCANI CENTRE Israel Net EU contribution € 296 250,00 Address Derech hamcabim 68 50250 Bet dagan See on map Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 BEN-GURION UNIVERSITY OF THE NEGEV Israel Net EU contribution € 650 000,00 Address . 84105 Beer sheva See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Spain Net EU contribution € 626 261,25 Address Calle serrano 117 28006 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION Australia Net EU contribution € 0,00 Address Clunies ross street csiro black mountain science and innovation park 2601 Acton act See on map Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 415 625,00 FEDERAZIONE EUROPEA DI ZOOTECNICA Italy Net EU contribution € 176 300,00 Address Via giuseppe tomassetti 3 a/1 00161 Roma See on map Region Centro (IT) Lazio Roma Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EUROPEAN FORUM OF FARM ANIMAL BREEDERS Netherlands Net EU contribution € 278 625,00 Address Silkeborg 75 2905 AT Capelle aan den ijssel See on map Region West-Nederland Zuid-Holland Groot-Rijnmond Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTITUT DE L'ELEVAGE France Net EU contribution € 112 856,25 Address Rue de bercy 149 75012 Paris See on map Region Ile-de-France Ile-de-France Val-de-Marne Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES Spain Net EU contribution € 101 475,00 Address Ctra c-59 km 12 torre marimon 08140 Caldes de montbui barcelona See on map Region Este Cataluña Barcelona Activity type Other Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INRAE TRANSFERT SAS France Net EU contribution € 400 000,00 Address Rue du docteur finlay 28 75015 Paris See on map Region Ile-de-France Ile-de-France Paris Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LUONNONVARAKESKUS Finland Net EU contribution € 688 400,00 Address Latokartanonkaari 9 00790 Helsinki See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LIETUVOS SVEIKATOS MOKSLU UNIVERSITETAS Lithuania Net EU contribution € 219 335,00 Address A mickeviciaus gatve 9 44307 Kaunas See on map Region Lietuva Vidurio ir vakarų Lietuvos regionas Kauno apskritis Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET Norway Net EU contribution € 620 560,00 Address Universitetstunet 3 1433 As See on map Region Norge Oslo og Viken Viken Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 NATIONAL UNIVERSITY OF IRELAND GALWAY Ireland Net EU contribution € 195 706,25 Address University road H91 Galway See on map Region Ireland Northern and Western West Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THE QUEEN'S UNIVERSITY OF BELFAST United Kingdom Net EU contribution € 953 126,00 Address University road lanyon building BT7 1NN Belfast See on map Region Northern Ireland Northern Ireland Belfast Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 SRUC United Kingdom Net EU contribution € 759 957,50 Address West mains road EH9 3JG Edinburgh See on map Region Scotland Eastern Scotland Edinburgh Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY Ireland Net EU contribution € 1 023 093,00 Address Oak park R93 Carlow See on map Region Ireland Southern South-East Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THE GOVERNORS OF THE UNIVERSITY OF ALBERTA Canada Net EU contribution € 0,00 Address 1-560 enterprise square 10230 jasper avenue research services office T5J 4P6 Edmonton alberta See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 213 600,00 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA United States Net EU contribution € 0,00 Address Franklin street 1111 12 floor 94607 Oakland ca See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 39 976,25 UNIVERSITEIT GENT Belgium Net EU contribution € 250 937,00 Address Sint pietersnieuwstraat 25 9000 Gent See on map Region Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,50 UNIVERSITAET GREIFSWALD Germany Net EU contribution € 346 250,00 Address Domstrasse 11 17489 Greifswald See on map Region Mecklenburg-Vorpommern Mecklenburg-Vorpommern Vorpommern-Greifswald Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 WAGENINGEN UNIVERSITY Netherlands Net EU contribution € 505 217,00 Address Droevendaalsesteeg 4 6708 PB Wageningen See on map Region Oost-Nederland Gelderland Veluwe Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,50