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Dynamic ubiquitin signalling coordinates transcriptional reprogramming in plant immunity

Project description

Harnessing ubiquitin signalling to boost plant protection

Dynamic regulation of gene expression is vital for all organisms and enables them to respond to the ever-changing environment. In response to pathogen attacks, plant cells display dramatic reprogramming of the transcriptome. The EU-funded UbRegulate project will explore the role of the immunising hormone salicylic acid (SA) in this process. SA employs the small post-translational modifier ubiquitin to establish durable immunity. It also induces dynamic modification of regulatory proteins with ubiquitin chains of diverse linkage types, generating the potential to control their functions and activities. The project aims to reveal how SA-induced ubiquitin signalling engages the transcriptional machinery and explore how this may be exploited by agrichemical biology.

Call for proposal

ERC-2020-COG
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Host institution

THE UNIVERSITY OF EDINBURGH
Address
Old College, South Bridge
EH8 9YL Edinburgh
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 000 000

Beneficiaries (1)

THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 2 000 000
Address
Old College, South Bridge
EH8 9YL Edinburgh
Activity type
Higher or Secondary Education Establishments